Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jochen Seebach"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1285 (2024)
Dendritic spines are essential for synaptic function because they constitute the postsynaptic compartment of the neurons that receives the most excitatory input. The extracellularly shorter variant of the presynaptic cell adhesion molecules neurexins
Externí odkaz:
https://doaj.org/article/70a975754dd746bba626f55d16b3e506
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Vascular endothelial cell (EC) junctions are key structures controlling tissue homeostasis in physiology. In the last three decades, excellent studies have addressed many aspects of this complex and highly dynamic regulation, including cell signaling
Externí odkaz:
https://doaj.org/article/304bc1c0c4994907a5f1ec56de8f9030
Autor:
Jiahui Cao, Manuel Ehling, Sigrid März, Jochen Seebach, Katsiaryna Tarbashevich, Tomas Sixta, Mara E. Pitulescu, Ann-Cathrin Werner, Boris Flach, Eloi Montanez, Erez Raz, Ralf H. Adams, Hans Schnittler
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-20 (2017)
The formation of new blood vessels requires both polarized cell migration and coordinated control of endothelial cell contacts. Here, Cao and colleagues describe at the sub-cellular level the cytoskeletal and cell junction dynamics regulating these p
Externí odkaz:
https://doaj.org/article/e445ed86f1b4415cb0e943b34a211150
Autor:
Muna Taha, Mohammed Aldirawi, Sigrid März, Jochen Seebach, Maria Odenthal-Schnittler, Olga Bondareva, Vesna Bojovic, Thomas Schmandra, Benedikt Wirth, Magdalena Mietkowska, Klemens Rottner, Hans Schnittler
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 1010-1026.e6 (2019)
Summary: Actin-binding proteins are essential for linear and branched actin filament dynamics that control shape change, cell migration, and cell junction remodeling in vascular endothelium (endothelial cells [ECs]). The epithelial protein lost in ne
Externí odkaz:
https://doaj.org/article/f9343d76d64a405abcd2f4daaebc78d2
Autor:
Kedar Ghimire, Jelena Zaric, Begoña Alday-Parejo, Jochen Seebach, Mélanie Bousquenaud, Jimmy Stalin, Grégory Bieler, Hans-Joachim Schnittler, Curzio Rüegg
Publikováno v:
Cells, Vol 8, Iss 5, p 388 (2019)
Fluid shear stress stimulates endothelial nitric oxide synthase (eNOS) activation and nitric oxide (NO) production through multiple kinases, including protein kinase A (PKA), AMP-activated protein kinase (AMPK), AKT and Ca2+/calmodulin-dependent prot
Externí odkaz:
https://doaj.org/article/cbe3fe3214924bfba1ef48d2265393c5
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65149 (2013)
SMC1 and SMC3 form a high-affinity heterodimer, which provides an open backbone of the cohesin ring, to be closed by a kleisin protein. RNAi mediated knock-down of either one heterodimer partner, SMC1 or SMC3, is expected to cause very similar if not
Externí odkaz:
https://doaj.org/article/2a188af69002428593c7e37e5b8b9fa3
Autor:
Volker Gerke, Hans J. Schnittler, Mikio Furuse, Luise Florin, Tetsuhisa Otani, Sonja Thölmann, Klaus Ebnet, Jochen Seebach
Junctional adhesion molecule (JAM)-A is a cell adhesion receptor localized at epithelial cellcell contacts with enrichment at the tight junctions. Its role during cell-cell contact formation and epithelial barrier formation has intensively been studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a279edac4d2ce27bf14d2eb106fed0ea
https://doi.org/10.21203/rs.3.rs-787948/v1
https://doi.org/10.21203/rs.3.rs-787948/v1
Autor:
Sonja Thölmann, Jochen Seebach, Tetsuhisa Otani, Luise Florin, Hans Schnittler, Volker Gerke, Mikio Furuse, Klaus Ebnet
Publikováno v:
Cellular and Molecular Life Sciences
Junctional adhesion molecule (JAM)-A is a cell adhesion receptor localized at epithelial cell–cell contacts with enrichment at the tight junctions. Its role during cell–cell contact formation and epithelial barrier formation has intensively been
Publikováno v:
Biophysical Journal. 116:1547-1559
Blood vessels are covered with endothelial cells on their inner surfaces, forming a selective and semipermeable barrier between the blood and the underlying tissue. Many pathological processes, such as inflammation or cancer metastasis, are accompani
Autor:
Rupert Hallmann, Maryam Rezaei, Jochen Seebach, Hermann Schillers, Stephan Niland, Ana C. Martins Cavaco, Jana Zimmermann, Johannes A. Eble, Eva-Maria Hanschmann
Publikováno v:
The Journal of Immunology. 202:1559-1572
The neuropilin-1 (NRP1)-MET signaling axis regulates the motility of individual endothelial cells (ECs). It is unknown how this signaling pathway affects the endothelial barrier in coherent ECs forming a tight monolayer. We hypothesized that it is in