Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jochen Schwenk"'
Autor:
Amanda M. Perozzo, Jochen Schwenk, Aichurok Kamalova, Terunaga Nakagawa, Bernd Fakler, Derek Bowie
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Transmembrane AMPA receptor regulatory proteins (TARPs) and germ cell-specific gene 1-like protein (GSG1L) are claudin-type AMPA receptor (AMPAR) auxiliary subunits that profoundly regulate glutamatergic synapse strength and plasticity. Whil
Externí odkaz:
https://doaj.org/article/ede067392f5f45719cbe9c020b122c3a
Autor:
Maciej K. Kocylowski, Hande Aypek, Wolfgang Bildl, Martin Helmstädter, Philipp Trachte, Bernhard Dumoulin, Sina Wittösch, Lukas Kühne, Ute Aukschun, Carolin Teetzen, Oliver Kretz, Botond Gaal, Akos Kulik, Corinne Antignac, Geraldine Mollet, Anna Köttgen, Burulca Göcmen, Jochen Schwenk, Uwe Schulte, Tobias B. Huber, Bernd Fakler, Florian Grahammer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The slit-diaphragm is a cellular junction that is crucial for blood filtration in the kidney. Kocylowski et al. show that the junction-spanning components are embedded in a protein network for dynamic control of filtration; network disturbance leads
Externí odkaz:
https://doaj.org/article/6b2ce777bb844f689ec4e628b7c40b09
Autor:
Pascal Dominic Rem, Vita Sereikaite, Diego Fernández-Fernández, Sebastian Reinartz, Daniel Ulrich, Thorsten Fritzius, Luca Trovo, Salomé Roux, Ziyang Chen, Philippe Rondard, Jean-Philippe Pin, Jochen Schwenk, Bernd Fakler, Martin Gassmann, Tania Rinaldi Barkat, Kristian Strømgaard, Bernhard Bettler
Publikováno v:
eLife, Vol 12 (2023)
Amyloid-β precursor protein (APP) regulates neuronal activity through the release of secreted APP (sAPP) acting at cell surface receptors. APP and sAPP were reported to bind to the extracellular sushi domain 1 (SD1) of GABAB receptors (GBRs). A 17 a
Externí odkaz:
https://doaj.org/article/f48ea31c4d5245788aa36e87dccbb8c4
Autor:
Margarita C. Dinamarca, Adi Raveh, Andy Schneider, Thorsten Fritzius, Simon Früh, Pascal D. Rem, Michal Stawarski, Txomin Lalanne, Rostislav Turecek, Myeongjeong Choo, Valérie Besseyrias, Wolfgang Bildl, Detlef Bentrop, Matthias Staufenbiel, Martin Gassmann, Bernd Fakler, Jochen Schwenk, Bernhard Bettler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The mechanisms that control the presynaptic abundance of GABAB receptors (GBRs) remains unclear. This study shows that sequence-related epitopes in APP, AJAP-1 and PIANP bind with nanomolar affinities to the N-terminal sushi-domain of presynaptic GBR
Externí odkaz:
https://doaj.org/article/1122aad37c3e4affaea79ae9d7612a6d
Autor:
Aline Brechet, Rebecca Buchert, Jochen Schwenk, Sami Boudkkazi, Gerd Zolles, Karine Siquier-Pernet, Irene Schaber, Wolfgang Bildl, Abdelkrim Saadi, Christine Bole-Feysot, Patrick Nitschke, Andre Reis, Heinrich Sticht, Nouriya Al-Sanna’a, Arndt Rolfs, Akos Kulik, Uwe Schulte, Laurence Colleaux, Rami Abou Jamra, Bernd Fakler
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The biogenesis of AMPA-type glutamate receptor (AMPAR) complexes is only partially understood. Here the authors identify transient assemblies of GluA1-4 proteins and proteins FRRS1l/CPT1c that drive formation of mature AMPAR complexes in the ER. Muta
Externí odkaz:
https://doaj.org/article/116ddb4d6f1445d88b45bc7aa135638e
Autor:
Sandeep Dembla, Marc Behrendt, Florian Mohr, Christian Goecke, Julia Sondermann, Franziska M Schneider, Marlene Schmidt, Julia Stab, Raissa Enzeroth, Michael G Leitner, Paulina Nuñez-Badinez, Jochen Schwenk, Bernd Nürnberg, Alejandro Cohen, Stephan E Philipp, Wolfgang Greffrath, Moritz Bünemann, Dominik Oliver, Eleonora Zakharian, Manuela Schmidt, Johannes Oberwinkler
Publikováno v:
eLife, Vol 6 (2017)
Opioids, agonists of µ-opioid receptors (µORs), are the strongest pain killers clinically available. Their action includes a strong central component, which also causes important adverse effects. However, µORs are also found on the peripheral endi
Externí odkaz:
https://doaj.org/article/17777c9aaefd44fe844bae6c04dc63f5
Autor:
Gukhan Kim, Rafael Luján, Jochen Schwenk, Melissa H Kelley, Carolina Aguado, Masahiko Watanabe, Bernd Fakler, James Maylie, John P Adelman
Publikováno v:
eLife, Vol 5 (2016)
Mouse CA1 pyramidal neurons express apamin-sensitive SK2-containing channels in the post-synaptic membrane, positioned close to NMDA-type (N-methyl-D-aspartate) glutamate receptors. Activated by synaptically evoked NMDAR-dependent Ca2+ influx, the sy
Externí odkaz:
https://doaj.org/article/27fe61ee549d445eb1c0bd9a967061c0
Autor:
Anders Malarstig, Felix Grassman, Leo Dahl, Marios Dimitriou, Dianna Mcleod, Marike Gabrielson, Karl Smith-Byrne, Cecilia Thomas, Tzu-Hsuan Huang, Simon Forsberg, Per Eriksson, Mikael Ulfstedt, Mattias Johansson, Aleksandr Sokolov, Helgi Schioth, Per Hall, Jochen Schwenk, Kamila Czene, Asa Hedman
The blood proteome reflects homeostatic and dynamic cellular processes across human organs. However, few blood proteomics studies of sufficient depth and size have been reported in breast cancer. To comprehensively identify circulating proteins with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d961e380004e395c550cad3a26792d
https://doi.org/10.21203/rs.3.rs-2749047/v1
https://doi.org/10.21203/rs.3.rs-2749047/v1
Autor:
Pascal Dominic Rem, Vita Sereikaite, Diego Fernández-Fernández, Sebastian Reinartz, Daniel Ulrich, Thorsten Fritzius, Luca Trovo, Salomé Roux, Ziyang Chen, Philippe Rondard, Jean-Philippe Pin, Jochen Schwenk, Bernd Fakler, Martin Gassmann, Tania Rinaldi Barkat, Kristian Strømgaard, Bernhard Bettler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa62afb60d007f8568f9449dc8cc51b
https://doi.org/10.7554/elife.82082.sa2
https://doi.org/10.7554/elife.82082.sa2
Publikováno v:
SCENTIA International Economic Review. 1:192-202
Many businesses face avoidable strategic and external risks that can be addressed by accepting, relocating, reducing, or eliminating them. Companies of all sizes should predict and prepare for the risks that come with doing business. When a scenario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2a3ae98c4be5860404d57520c61e581
https://doi.org/10.52514/sier.v1i1.16
https://doi.org/10.52514/sier.v1i1.16