Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jochen Imig"'
Autor:
Kim Denise Fischer, Shashank Tiwari, Beatrice Thier, Lin Christina Qiu, Tzu-Chen Lin, Annette Paschen, Jochen Imig
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Melanoma is a highly malignant tumor, that stands as the most lethal form of skin cancer and is characterized by notable phenotypic plasticity and intratumoral heterogeneity. Melanoma plasticity is involved in tumor growth, metastasis and therapy res
Externí odkaz:
https://doaj.org/article/8d8688860dd44810ae450695d526d633
Autor:
Sama Shamloo, Andreas Kloetgen, Stavroula Petroulia, Kathryn Hockemeyer, Sonja Sievers, Aristotelis Tsirigos, Ioannis Aifantis, Jochen Imig
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2054 (2023)
The incidence of melanoma, being one of the most commonly occurring cancers, has been rising since the past decade. Patients at advanced stages of the disease have very poor prognoses, as opposed to at the earlier stages. The conventional targeted th
Externí odkaz:
https://doaj.org/article/56feef583c634387957347298adc9d9a
Autor:
Saul Carcamo, Christie B. Nguyen, Elena Grossi, Dan Filipescu, Aktan Alpsoy, Alisha Dhiman, Dan Sun, Sonali Narang, Jochen Imig, Tiphaine C. Martin, Ramon Parsons, Iannis Aifantis, Aristotelis Tsirigos, Julio A. Aguirre-Ghiso, Emily C. Dykhuizen, Dan Hasson, Emily Bernstein
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110637- (2022)
Summary: ARID2 is the most recurrently mutated SWI/SNF complex member in melanoma; however, its tumor-suppressive mechanisms in the context of the chromatin landscape remain to be elucidated. Here, we model ARID2 deficiency in melanoma cells, which r
Externí odkaz:
https://doaj.org/article/6ee77d1cfbd846c4b902e2327217d8be
Autor:
Valentina Vongrad, Jochen Imig, Pejman Mohammadi, Shivendra Kishore, Lukasz Jaskiewicz, Jonathan Hall, Huldrych F Günthard, Niko Beerenwinkel, Karin J Metzner
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132127 (2015)
BACKGROUND:MiRNAs and other small noncoding RNAs (sncRNAs) are key players in post-transcriptional gene regulation. HIV-1 derived small noncoding RNAs (sncRNAs) have been described in HIV-1 infected cells, but their biological functions still remain
Externí odkaz:
https://doaj.org/article/07a157720b9d4c299ef111f384c70e2b
Autor:
Natalie Motsch, Julia Alles, Jochen Imig, Jiayun Zhu, Stephanie Barth, Tanja Reineke, Marianne Tinguely, Sergio Cogliatti, Anne Dueck, Gunter Meister, Christoph Renner, Friedrich A Grässer
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42193 (2012)
The Epstein-Barr virus (EBV) is an oncogenic human Herpes virus involved in the pathogenesis of nasal NK/T-cell lymphoma. EBV encodes microRNAs (miRNAs) and induces changes in the host cellular miRNA profile. MiRNAs are short non-coding RNAs of about
Externí odkaz:
https://doaj.org/article/3efd3d4446bd4765815736f42491fe02
Autor:
Alexander Kanitz, Jochen Imig, Piotr J Dziunycz, Adriana Primorac, Alessia Galgano, Günther F L Hofbauer, André P Gerber, Michael Detmar
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49568 (2012)
Vascular endothelial growth factor A (VEGFA) plays a key role in the angiogenesis of human skin. Elevated levels of VEGFA are associated with several pathological conditions, including chronic inflammatory skin diseases and several types of skin canc
Externí odkaz:
https://doaj.org/article/a2dae89c986443249a9cf86ff0e7c1c0
Autor:
Fischer, Kim Denise, Tiwari, Shashank, Thier, Beatrice, Qiu, Lin Christina, Tzu-Chen Lin, Paschen, Annette, Jochen Imig
Publikováno v:
Frontiers in Molecular Biosciences; 2024, p1-17, 17p
Autor:
Saul Carcamo, Christie B. Nguyen, Elena Grossi, Dan Filipescu, Aktan Alpsoy, Alisha Dhiman, Dan Sun, Sonali Narang, Jochen Imig, Tiphaine C. Martin, Ramon Parsons, Iannis Aifantis, Aristotelis Tsirigos, Julio A. Aguirre-Ghiso, Emily C. Dykhuizen, Dan Hasson, Emily Bernstein
Publikováno v:
Cell reports. 39(1)
ARID2 is the most recurrently mutated SWI/SNF complex member in melanoma; however, its tumor-suppressive mechanisms in the context of the chromatin landscape remain to be elucidated. Here, we model ARID2 deficiency in melanoma cells, which results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2def16a5248bd58eba97aca2a63e4ee0
https://pubmed.ncbi.nlm.nih.gov/35385731
https://pubmed.ncbi.nlm.nih.gov/35385731
Autor:
Jimin, Hwang, Xiaqiu, Qiu, Lydia, Borgelt, Neele, Haacke, Laurin, Kanis, Stavroula, Petroulia, Raphael, Gasper, Damian, Schiller, Philipp, Lampe, Sonja, Sievers, Jochen, Imig, Peng, Wu
Publikováno v:
Bioorganic & Medicinal Chemistry. 58:116653
Aminothiophene is a scaffold that is widely present in drugs and biologically active small molecules as chemical probes. In this study, 43 compounds sharing a 2-aminothiophenone-3-carboxylate (ATPC) scaffold, known to activate the ribonuclease L (RNa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64115988e97dc5b0362db46b8390c494
https://doi.org/10.1016/j.bmc.2022.116653
https://doi.org/10.1016/j.bmc.2022.116653
Autor:
Adrian R. Krainer, Kathryn Hockemeyer, Iannis Aifantis, Raoul Tibes, Yohana Ghebrechristos, Alessandro Pastore, Daichi Inoue, Akihide Yoshimi, Eric Wang, Sydney X. Lu, Taisuke Uehara, Xufeng Chen, Lillian Bitner, Michelle Ki, Jochen Imig, Kuan-Ting Lin, Takashi Owa, Omar Abdel-Wahab, Stanley Chun-Wei Lee, Andreas Kloetgen, Hana Cho
RNA-binding proteins (RBPs) are essential modulators of transcription and translation frequently dysregulated in cancer. We systematically interrogated RBP dependencies in human cancers using a comprehensive CRISPR/Cas9 domain-focused screen targetin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cebdc74db0f6f3998389e75972f64b1
https://europepmc.org/articles/PMC6424627/
https://europepmc.org/articles/PMC6424627/
