Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jochen HM. Prehn"'
Autor:
Parvathi A. Myer, Hyunjin Kim, Anna M. Blümel, Ellen Finnegan, Alexander Kel, Taylor V. Thompson, John M. Greally, Jochen HM. Prehn, Darran P. O’Connor, Richard A. Friedman, Aris Floratos, Sudipto Das
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 3, Pp 328-341 (2022)
Background and Aims: Individuals of African (AFR) ancestry have a higher incidence of colorectal cancer (CRC) than those of European (EUR) ancestry and exhibit significant health disparities. Previous studies have noted differences in the tumor micro
Externí odkaz:
https://doaj.org/article/18a7ea9fffb34eac8439f8f87e7ef340
Autor:
Deborah A McNamara, Jinru Shia, John P Burke, Manuela Salvucci, Daniel B Longley, Fiona Ginty, Andreas Lindner, Sanghee Cho, Elizabeth McDonough, John Graf, Canan Firat, Nil Urganci, Christine Surrette, Anna Matveeva, Batuhan Kisakol, Anthony O’Grady, Mohammadreza Azimi, Simon McDade, Jochen HM Prehn
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective Inducing tumour cell apoptosis is a primary objective of chemotherapy but, to date, there are no validated biomarkers of apoptosis sensitivity or resistance. Our objective was to image multiple apoptosis pathway proteins at single cell leve
Externí odkaz:
https://doaj.org/article/59942d4fee7b4e8199fc8767f377b824
Autor:
Hajrah Khawaja, Rebecca Briggs, Cheryl Latimer, Md A.M.B Rassel, Daryl Griffin, Lyndsey Hanson, Alberto Bardelli, Federica Di Nicolantonio, Simon McDade, Christopher Scott, Shauna Lambe, Manisha Maurya, Andreas Ulrich Lindner, Jochen HM Prehn, Jose Sousa, Chris Winnington, Melissa J LaBonte, Sarah Ross, Sandra Van Schaeybroeck
Publikováno v:
Journal of Clinical Oncology. 40:3557-3557
3557 Background: Novel covalent inhibitors of KRASG12C have shown modest response rates in KRASG12C mutant (MT) colorectal cancer (CRC) patients. Thus, novel KRASG12C inhibitor combination strategies that can achieve deep and durable responses are ne
Autor:
Aidan, Kenny, Félix, Hernández, Jesús, Avila, José J, Lucas, David C, Henshall, Jochen Hm, Prehn, Eva M, Jiménez-Mateos, Tobias, Engel
Publikováno v:
International journal of physiology, pathophysiology and pharmacology. 10(6)
Tauopathies are a group of neurodegenerative diseases characterized by the pathological aggregation of the microtubule-associated protein tau. These include more than 20 diseases, with Alzheimer’s disease being the most frequent. While pathological