Zobrazeno 1 - 10
of 313
pro vyhledávání: '"Jochen Guck"'
Autor:
Sefora Conti, Valeria Venturini, Adrià Cañellas-Socias, Carme Cortina, Juan F. Abenza, Camille Stephan-Otto Attolini, Emily Middendorp Guerra, Catherine K. Xu, Jia Hui Li, Leone Rossetti, Giorgio Stassi, Pere Roca-Cusachs, Alba Diz-Muñoz, Verena Ruprecht, Jochen Guck, Eduard Batlle, Anna Labernadie, Xavier Trepat
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Colorectal cancer (CRC) tumors are composed of heterogeneous and plastic cell populations, including a pool of cancer stem cells that express LGR5. Whether these distinct cell populations display different mechanical properties, and how thes
Externí odkaz:
https://doaj.org/article/f3eda4b90df041b09e2517b0f47ce22e
Autor:
Conrad Möckel, Timon Beck, Sara Kaliman, Shada Abuhattum, Kyoohyun Kim, Julia Kolb, Daniel Wehner, Vasily Zaburdaev, Jochen Guck
Publikováno v:
Biophysical Reports, Vol 4, Iss 2, Pp 100156- (2024)
The quantification of physical properties of biological matter gives rise to novel ways of understanding functional mechanisms. One of the basic biophysical properties is the mass density (MD). It affects the dynamics in sub-cellular compartments and
Externí odkaz:
https://doaj.org/article/31d1a4302fc44a82b58c7d924d8e8af7
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Optical tomography has emerged as a non-invasive imaging method, providing three-dimensional insights into subcellular structures and thereby enabling a deeper understanding of cellular functions, interactions, and processes. Conventional op
Externí odkaz:
https://doaj.org/article/1807668e2e804805b52bf61a55aed2f2
Autor:
Julia Kolb, Vasiliki Tsata, Nora John, Kyoohyun Kim, Conrad Möckel, Gonzalo Rosso, Veronika Kurbel, Asha Parmar, Gargi Sharma, Kristina Karandasheva, Shada Abuhattum, Olga Lyraki, Timon Beck, Paul Müller, Raimund Schlüßler, Renato Frischknecht, Anja Wehner, Nicole Krombholz, Barbara Steigenberger, Dimitris Beis, Aya Takeoka, Ingmar Blümcke, Stephanie Möllmert, Kanwarpal Singh, Jochen Guck, Katja Kobow, Daniel Wehner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Extracellular matrix (ECM) deposition after central nervous system (CNS) injury leads to inhibitory scarring in humans and other mammals, whereas it facilitates axon regeneration in the zebrafish. However, the molecular basis of these differ
Externí odkaz:
https://doaj.org/article/10277ae948b34c2798d29b570c3957d7
Autor:
Felix Pfister, Jan Dörrie, Niels Schaft, Vera Buchele, Harald Unterweger, Lucas R. Carnell, Patrick Schreier, Rene Stein, Markéta Kubánková, Jochen Guck, Holger Hackstein, Christoph Alexiou, Christina Janko
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundImmunotherapy of cancer is an emerging field with the potential to improve long-term survival. Thus far, adoptive transfer of tumor-specific T cells represents an effective treatment option for tumors of the hematological system such as lym
Externí odkaz:
https://doaj.org/article/46cbcad70ccd47019395acaf9ee98ab1
Autor:
Vugar Azizov, Michel Hübner, Michael Frech, Jörg Hofmann, Marketa Kubankova, Dennis Lapuente, Matthias Tenbusch, Jochen Guck, Georg Schett, Mario M. Zaiss
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107230- (2023)
Summary: Alcohol is among the most widely consumed dietary substances. Excessive alcohol consumption damages the liver, heart, and brain. Alcohol also has strong immunoregulatory properties. Here, we report how alcohol impairs T cell function via ace
Externí odkaz:
https://doaj.org/article/4f38ace1511c4f95970755bb2e6a147e
Autor:
Agata Nyga, Katarzyna Plak, Martin Kräter, Marta Urbanska, Kyoohyun Kim, Jochen Guck, Buzz Baum
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106696- (2023)
Summary: Animal cells undergo repeated shape changes, for example by rounding up and respreading as they divide. Cell rounding can be also observed in interphase cells, for example when cancer cells switch from a mesenchymal to an ameboid mode of cel
Externí odkaz:
https://doaj.org/article/d129827eb7524fbdb521520b5a1fbf80
Autor:
Marcus Gutmann, Jana Bachir Salvador, Paul Müller, Kyoohyun Kim, Martin Schicht, Serhii Aif, Friedrich Paulsen, Lorenz Meinel, Jochen Guck, Stephanie Möllmert
Publikováno v:
JPhys Photonics, Vol 6, Iss 3, p 035020 (2024)
Mechanical tissue properties increasingly serve as pivotal phenotypic characteristics that are subject to change during development or pathological progression. The quantification of such material properties often relies on physical contact between a
Externí odkaz:
https://doaj.org/article/1b40cf0a9ced4762a971d443e3847d4b
Autor:
Jiawei Sun, Jiachen Wu, Song Wu, Ruchi Goswami, Salvatore Girardo, Liangcai Cao, Jochen Guck, Nektarios Koukourakis, Juergen W. Czarske
Publikováno v:
Light: Science & Applications, Vol 11, Iss 1, Pp 1-10 (2022)
Graphical abstract for Quantitative phase imaging through an ultra-thin lensless fiber endoscope.
Externí odkaz:
https://doaj.org/article/7afec24387094dbf93ae67a06bdcbedd
Autor:
Shada Abuhattum, Petra Kotzbeck, Raimund Schlüßler, Alexandra Harger, Angela Ariza de Schellenberger, Kyoohyun Kim, Joan-Carles Escolano, Torsten Müller, Jürgen Braun, Martin Wabitsch, Matthias Tschöp, Ingolf Sack, Marko Brankatschk, Jochen Guck, Kerstin Stemmer, Anna V. Taubenberger
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Adipose tissue expansion involves both differentiation of new precursors and size increase of mature adipocytes. While the two processes are well balanced in healthy tissues, obesity and diabetes type II are associated with abnormally enlarg
Externí odkaz:
https://doaj.org/article/d5ed2708d75f45e88b13545aa722713e