Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Jochen, Roeper"'
Autor:
Nadine J. Ortner, Anupam Sah, Enrica Paradiso, Josef Shin, Strahinja Stojanovic, Niklas Hammer, Maria Haritonova, Nadja T. Hofer, Andrea Marcantoni, Laura Guarina, Petronel Tuluc, Tamara Theiner, Florian Pitterl, Karl Ebner, Herbert Oberacher, Emilio Carbone, Nadia Stefanova, Francesco Ferraguti, Nicolas Singewald, Jochen Roeper, Jörg Striessnig
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Germline de novo missense variants of the CACNA1D gene, encoding the pore-forming α1 subunit of Cav1.3 L-type Ca2+ channels (LTCCs), have been found in patients with neurodevelopmental and endocrine dysfunction, but their disease-causing potential i
Externí odkaz:
https://doaj.org/article/6c217573f67344608c7a051a8ed2797f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Heterozygous mice that express Cre-recombinase under the dopamine transporter promoter (DAT-Cre knock in mice, or KI) are widely used for targeting midbrain dopamine neurons, under the assumption that their constitutive physiology is not aff
Externí odkaz:
https://doaj.org/article/a101a97424ee439d9932956e44813678
Autor:
Kanako Otomo, Jessica Perkins, Anand Kulkarni, Strahinja Stojanovic, Jochen Roeper, Carlos A. Paladini
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The in vivo firing patterns of ventral midbrain dopamine neurons are controlled by afferent and intrinsic activity. The authors identified biophysical membrane potential signatures associated with distinct in vivo firing patterns in whole-cell record
Externí odkaz:
https://doaj.org/article/71ce2d57d3964684b746a32f25f34cfc
Autor:
Alexis Cooper, Tamer Butto, Niklas Hammer, Somanath Jagannath, Desiree Lucia Fend-Guella, Junaid Akhtar, Konstantin Radyushkin, Florian Lesage, Jennifer Winter, Susanne Strand, Jochen Roeper, Ulrich Zechner, Susann Schweiger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Birk-Barel intellectual disability is an imprinting syndrome due to maternally-only transmitted mutations of KCNK9/TASK3. Here authors are using a heterozygous deletion of the active maternal Kcnk9 allele to model the disease and show phenotypic resc
Externí odkaz:
https://doaj.org/article/fea75db2dad1436d96f90d9e76ec3153
Autor:
Jochen Roeper, Jasmin Reichert-Schlax, Olga Zlatkin-Troitschanskaia, Verena Klose, Maruschka Weber, Marie-Theres Nagel
Publikováno v:
Frontiers in Psychology, Vol 12 (2022)
Research FocusThe promotion of domain-specific knowledge is a central goal of higher education and, in the field of medicine, it is particularly essential to promote global health. Domain-specific knowledge on its own is not exhaustive; confidence re
Externí odkaz:
https://doaj.org/article/efc8d7d6d29c49d2a242a143b45e09eb
Autor:
Trinidad Montero, Rafael Ignacio Gatica, Navid Farassat, Rodrigo Meza, Cristian González-Cabrera, Jochen Roeper, Pablo Henny
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
The firing activity of ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) dopaminergic (DA) neurons is an important factor in shaping DA release and its role in motivated behavior. Dendrites in DA neurons are the main postsynaptic
Externí odkaz:
https://doaj.org/article/f77c2c966d5d4dcd94bce9ed2b92ce06
Autor:
Anastassios Karagiannis, Thierry Gallopin, Alexandre Lacroix, Fabrice Plaisier, Juliette Piquet, Hélène Geoffroy, Régine Hepp, Jérémie Naudé, Benjamin Le Gac, Richard Egger, Bertrand Lambolez, Dongdong Li, Jean Rossier, Jochen F Staiger, Hiromi Imamura, Susumu Seino, Jochen Roeper, Bruno Cauli
Publikováno v:
eLife, Vol 10 (2021)
Glucose is the mandatory fuel for the brain, yet the relative contribution of glucose and lactate for neuronal energy metabolism is unclear. We found that increased lactate, but not glucose concentration, enhances the spiking activity of neurons of t
Externí odkaz:
https://doaj.org/article/57bb3a9ac2944ab2882e68666a6d4e9e
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009371 (2021)
Two subpopulations of midbrain dopamine (DA) neurons are known to have different dynamic firing ranges in vitro that correspond to distinct projection targets: the originally identified conventional DA neurons project to the dorsal striatum and the l
Externí odkaz:
https://doaj.org/article/2616b063653f4776b914dab9d45f7960
Autor:
Susanne Schmidt, Olga Zlatkin-Troitschanskaia, Jochen Roeper, Verena Klose, Maruschka Weber, Ann-Kathrin Bültmann, Sebastian Brückner
Publikováno v:
Frontiers in Psychology, Vol 11 (2020)
To successfully learn using open Internet resources, students must be able to critically search, evaluate and select online information, and verify sources. Defined as critical online reasoning (COR), this construct is operationalized on two levels i
Externí odkaz:
https://doaj.org/article/9fe9a7af7d7440b394d3b5e73779f4c1
Publikováno v:
Frontiers in Education, Vol 5 (2020)
The digital and information age has fundamentally transformed the way in which students learn and the study material they have at their disposal, especially in higher education. Students need to possess a number of higher-order cognitive and metacogn
Externí odkaz:
https://doaj.org/article/5557877627464bd79cfe3ab002fe6ba3