Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Jochen, Mattner"'
Autor:
Jochen Mattner
Publikováno v:
Clinical and Translational Discovery, Vol 4, Iss 5, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/a81ef080ba7a4871aa86ee12d83029aa
Autor:
Tim Holland, Jochen Mattner
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/0c87f3a898ce48cc82a217a805bc1456
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTL-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple metabolic pathways in the regulation of cell division and growth. It also
Externí odkaz:
https://doaj.org/article/39128c3b4e7548d29cad95805c959f63
Autor:
Alan Bénard, Anke Mittelstädt, Bettina Klösch, Karolina Glanz, Jan Müller, Janina Schoen, Björn Nüse, Maximilian Brunner, Elisabeth Naschberger, Michael Stürzl, Jochen Mattner, Luis E. Muñoz, Kai Sohn, Robert Grützmann, Georg F. Weber
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112637- (2023)
Summary: Inflammatory bowel diseases (IBDs) are a global health issue with an increasing incidence. Although the pathogenesis of IBDs has been investigated intensively, the etiology of IBDs remains enigmatic. Here, we report that interleukin-3 (Il-3)
Externí odkaz:
https://doaj.org/article/ab94f5f804be455fbd0c5053f6f6b6d7
Autor:
Katrin Peckert-Maier, Pia Langguth, Astrid Strack, Lena Stich, Petra Mühl-Zürbes, Christine Kuhnt, Christina Drassner, Elisabeth Zinser, Marius Wrage, Jochen Mattner, Alexander Steinkasserer, Dmytro Royzman, Andreas B. Wild
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Excessive macrophage (Mφ) activation results in chronic inflammatory responses or autoimmune diseases. Therefore, identification of novel immune checkpoints on Mφ, which contribute to resolution of inflammation, is crucial for the development of ne
Externí odkaz:
https://doaj.org/article/1a0d798c26b848068ab4b38b25d588a3
Autor:
Ann-Sophie Kaemmerer, Francesco Ciotola, Walter Geißdörfer, Frank Harig, Jochen Mattner, Timo Seitz, Mathieu N. Suleiman, Michael Weyand, Christian Heim
Publikováno v:
Pathogens, Vol 12, Iss 9, p 1130 (2023)
Infective endocarditis (IE) is still a life-threatening disease with high morbidity and mortality. While usually caused by a single bacterium, poly-microbial infective endocarditis (IE) is rare. Here, we report a (blood-culture-negative) dual pathoge
Externí odkaz:
https://doaj.org/article/4b9d400a41104686855de0175d04fd8a
Autor:
Björn Nüse, Jochen Mattner
Publikováno v:
Exploration of Immunology, Vol 1, Iss 2, Pp 80-89 (2021)
Arginase-1 (Arg1) and the inducible nitric oxide synthase 2 (NOS2) compete for the common substrate L-arginine, semi-essential amino acid, and central intestinal metabolite. Both enzymes exhibit various, sometimes opposing effects on immune responses
Externí odkaz:
https://doaj.org/article/795628a54bfe46eca020af5f2c59efd8
Autor:
Stefan Vogt, Jochen Mattner
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Innate (-like) T lymphocytes such as natural killer T (NKT) cells play a pivotal role in the recognition of microbial infections and their subsequent elimination. They frequently localize to potential sites of pathogen entry at which they survey extr
Externí odkaz:
https://doaj.org/article/a072c4f8e17f46efa98f4c4ebafe777f
Publikováno v:
International Journal of Medical Microbiology, Vol 311, Iss 4, Pp 151497- (2021)
Intestinal microbiota signal to local and distant tissues in the body. Thus, they also regulate biochemical, metabolic and immunological processes in the gut and in the pancreas. Vice versa, eating habits or the immune system of the host shape the in
Externí odkaz:
https://doaj.org/article/4ed778cfe4754c19850fe3808f6b561f
Autor:
Jochen Mattner, Javid P Mohammed, Michael E Fusakio, Claudia Giessler, Carl-Philipp Hackstein, Robert Opoka, Marius Wrage, Regina Schey, Jan Clark, Heather I Fraser, Daniel B Rainbow, Linda S Wicker
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008178 (2019)
Type 1 diabetes (T1D) is a chronic multi-factorial disorder characterized by the immune-mediated destruction of insulin-producing pancreatic beta cells. Variations at a large number of genes influence susceptibility to spontaneous autoimmune T1D in n
Externí odkaz:
https://doaj.org/article/68695eaca1e54bc6800377987faee9a5