Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jochem N.A. Vink"'
Autor:
Sebastian N. Kieper, Cristóbal Almendros, Juliane Behler, Rebecca E. McKenzie, Franklin L. Nobrega, Anna C. Haagsma, Jochem N.A. Vink, Wolfgang R. Hess, Stan J.J. Brouns
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3377-3384 (2018)
Summary: CRISPR-Cas systems adapt their immunological memory against their invaders by integrating short DNA fragments into clustered regularly interspaced short palindromic repeat (CRISPR) loci. While Cas1 and Cas2 make up the core machinery of the
Externí odkaz:
https://doaj.org/article/a553cb692f094045896dfc2de824af60
Publikováno v:
Trends in Microbiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b11763e9ad12c4de0007fb1847b32d8
https://doi.org/10.1016/j.tim.2023.03.017
https://doi.org/10.1016/j.tim.2023.03.017
Publikováno v:
PhytoFrontiers™.
Phytophthora are eukaryotic microbes that cause disease in a wide range of agriculturally and ecologically important plants. During the Phytophthora disease cycle, thick-walled oospores can be produced via homothallic sexual reproduction. These resti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67bf69505f462930b9932405e81f8912
https://doi.org/10.1094/phytofr-11-22-0140-ta
https://doi.org/10.1094/phytofr-11-22-0140-ta
Autor:
Jochem N.A. Vink, Emma M. Keizer, Christian Fleck, Vera Kalkman, Jasper van Lopik, Sander J. Tans, Stan J. J. Brouns, Ferhat Büke, Rebecca E. McKenzie
Publikováno v:
Molecular Systems Biology, 18(4)
bioRxiv
Molecular Systems Biology 18 (2022) 4
Molecular Systems Biology
biorxiv
bioRxiv
Molecular Systems Biology 18 (2022) 4
Molecular Systems Biology
biorxiv
CRISPR-Cas defence is a combination of adaptation to new invaders by spacer acquisition, and interference by targeted nuclease activity. While these processes have been studied on a population level, the individual cellular variability has remained u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c67b03f7812ff279a4a42d6759f3761
https://doi.org/10.15252/msb.202110680
https://doi.org/10.15252/msb.202110680
Phytophthoraare eukaryotic microbes that cause disease in a wide range of agriculturally and ecologically important plants. During thePhytophthoradisease cycle, thick-walled oospores can be produced via sexual reproduction. These resting spores can s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfc86b9a8cdcadd5c8bbd2bae0986b3c
https://doi.org/10.1101/2021.10.17.464154
https://doi.org/10.1101/2021.10.17.464154
Autor:
Jochem N.A. Vink, Cristóbal Almendros, Saket R. Bagde, Ailong Ke, Anna C. Haagsma, Chunyi Hu, Ana Rita Costa, Ki Hyun Nam, Stan J. J. Brouns
Publikováno v:
Nature
Nature: international weekly journal of science, 598(7881)
Nature: international weekly journal of science, 598(7881)
Prokaryotes adapt to challenges from mobile genetic elements by integrating spacers derived from foreign DNA in the CRISPR array1. Spacer insertion is carried out by the Cas1–Cas2 integrase complex2–4. A substantial fraction of CRISPR–Cas syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53581050aa52660499ff98e9b4670f3f
https://europepmc.org/articles/PMC9164213/
https://europepmc.org/articles/PMC9164213/
Autor:
Jochem N.A. Vink, Stan J. J. Brouns, Sam P. B. van Beljouw, Anna C. Haagsma, Alicia Rodríguez-Molina, Daan F. van den Berg
Publikováno v:
Science (New York, N.Y.), 373(6561)
Type III CRISPR-Cas immunity is widespread in prokaryotes and is generally mediated by multi-subunit effector complexes. These complexes recognize complementary viral transcripts and can activate ancillary immune proteins. Here, we describe a type II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03849e097a522cedbf9205056e1fe63e
https://pubmed.ncbi.nlm.nih.gov/34799728
https://pubmed.ncbi.nlm.nih.gov/34799728
The adaptive CRISPR-Cas immune system stores sequences from past invaders as spacers in CRISPR arrays and thereby provides direct evidence that links invaders to hosts. Mapping CRISPR spacers has revealed many aspects of CRISPR biology, including tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d8d25b69e5d045a1d0c8fe8632fd6a
https://doi.org/10.1101/2021.05.04.442622
https://doi.org/10.1101/2021.05.04.442622
Publikováno v:
Genome Biology (Online), 22(1)
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Genome Biology
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Genome Biology
Background The adaptive CRISPR-Cas immune system stores sequences from past invaders as spacers in CRISPR arrays and thereby provides direct evidence that links invaders to hosts. Mapping CRISPR spacers has revealed many aspects of CRISPR-Cas biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf630f62ff254e5a461da1610255a6a
http://resolver.tudelft.nl/uuid:ae10e1df-3ac5-4710-bea3-787c9e909dba
http://resolver.tudelft.nl/uuid:ae10e1df-3ac5-4710-bea3-787c9e909dba
Autor:
Rebecca E. McKenzie, Cristóbal Almendros, Johannes Hohlbein, Marnix Vlot, Jochem N.A. Vink, Koen Martens, Daan J.W. Brocken, Stan J. J. Brouns, Boris Estrada Bonilla
Publikováno v:
Molecular Cell 77 (2020) 1
Molecular Cell, 77(1), 39-50.e10
Molecular Cell
Molecular Cell, 77(1), 39-50.e10
Molecular Cell
CRISPR-Cas systems encode RNA-guided surveillance complexes to find and cleave invading DNA elements. While it is thought that invaders are neutralized minutes after cell entry, the mechanism and kinetics of target search and its impact on CRISPR pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ae771e6a655e25881235c7588c2894
https://research.wur.nl/en/publications/direct-visualization-of-native-crispr-target-search-in-live-bacte
https://research.wur.nl/en/publications/direct-visualization-of-native-crispr-target-search-in-live-bacte