Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jocelyne N. Hanquier"'
Autor:
Christine A. Berryhill, Emma H. Doud, Jocelyne N. Hanquier, Whitney R. Smith-Kinnaman, Devon L. McCourry, Amber L. Mosley, Evan M. Cornett
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 817 (2024)
DZNep (3-deazaneplanocin A) is commonly used to reduce lysine methylation. DZNep inhibits S-adenosyl-l-homocysteine hydrolase (AHCY), preventing the conversion of S-adenosyl-l-homocysteine (SAH) into L-homocysteine. As a result, the SAM-to-SAH ratio
Externí odkaz:
https://doaj.org/article/3affc577ee8d49dc8c5f0c2dd1b4fb8b
Autor:
Christine A. Berryhill, Jocelyne N. Hanquier, Emma H. Doud, Eric Cordeiro-Spinetti, Bradley M. Dickson, Scott B. Rothbart, Amber L. Mosley, Evan M. Cornett
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Lysine methylation modulates the function of histone and non-histone proteins, and the enzymes that add or remove lysine methylation—lysine methyltransferases (KMTs) and lysine demethylases (KDMs), respectively—are frequently mutated and
Externí odkaz:
https://doaj.org/article/6311fa555be4463283a2990dcdaf5815
Autor:
Jocelyne N. Hanquier, Kenidi Sanders, Christine A. Berryhill, Firoj K. Sahoo, Andy Hudmon, Jonah Z. Vilseck, Evan M. Cornett
Lysine methylation is a dynamic, post-translational mark that regulates the function of histone and non-histone proteins. Many of the enzymes that mediate lysine methylation, known as lysine methyltransferases (KMTs), were originally identified to mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09a411b6303bb1d5824db3a8508a8ef2
https://doi.org/10.1101/2022.10.12.511945
https://doi.org/10.1101/2022.10.12.511945
Autor:
Jocelyne N. Hanquier, Kenidi Sanders, Christine A. Berryhill, Firoj K. Sahoo, Andy Hudmon, Jonah Z. Vilseck, Evan M. Cornett
Publikováno v:
Journal of Biological Chemistry. 299:104651
Autor:
Qiujia Chen, Alison M. Bates, Jocelyne N. Hanquier, Edward Simpson, Douglas B. Rusch, Ram Podicheti, Yunlong Liu, Ronald C. Wek, Evan M. Cornett, Millie M. Georgiadis
Publikováno v:
The Journal of biological chemistry. 298(5)
Extensive portions of the human genome have unknown function, including those derived from transposable elements. One such element, the DNA transposon Hsmar1, entered the primate lineage approximately 50 million years ago leaving behind terminal inve