Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jocelyne E. Kaufmann"'
Autor:
Paolo Meda, Jean-Marc Massé, Jocelyne E. Kaufmann, Egbert K. O. Kruithof, Ulrich M. Vischer, Denise Huber, Elisabeth M. Cramer
Publikováno v:
Blood, Vol. 99, No 10 (2002) pp. 3637-45
Vascular endothelial cells are thought to be the main source of plasma tissue-type plasminogen activator (t-PA) and von Willebrand factor (VWF). Previous studies have suggested that both t-PA and VWF are acutely released in response to the same stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434e8f4c33740a1baffa3b46caf3f414
https://doi.org/10.1182/blood.v99.10.3637
https://doi.org/10.1182/blood.v99.10.3637
Publikováno v:
Biochemical Journal, Vol. 310, No 3 (1995) pp. 869-874
Proinsulin is converted into insulin by the action of two endoproteases. Type I (PC1/PC3) is thought to cleave between the B-chain and the connecting peptide (C-peptide) and type II (PC2) between the C-peptide and the A-chain. An acidic region immedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7151a4513628d05313d70513f452fac
https://doi.org/10.1042/bj3100869
https://doi.org/10.1042/bj3100869
Autor:
Jocelyne E. Kaufmann, Stanislav Fakan, Antonio P. Silva, Eric Grouzmann, Phillip Shaw, Ulrich M. Vischer, Hans R. Brunner, Cláudia Cavadas, Cécile Vivancos
Publikováno v:
Biology of the cell. 97(6)
Background information. NPY (neuropeptide Y) may have an effect on the properties of vascular endothelial cells such as pro-angiogenic effects and potentiation of noradrenaline-induced vasoconstriction. In HUVEC (human umbilical-vein endothelial cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f48c792f40a77e173f76273aba80ea3
https://pubmed.ncbi.nlm.nih.gov/15850450
https://pubmed.ncbi.nlm.nih.gov/15850450
Autor:
Ulrich M. Vischer, Claes B. Wollheim, Jocelyne E. Kaufmann, Gabriele Günther, Alexander Oksche, Walter Rosenthal
Publikováno v:
Journal of Clinical Investigation, Vol. 106, No 1 (2000) pp. 107-16
Vasopressin and its analogue 1-deamino-8-D-arginine vasopressin (DDAVP) are known to raise plasma von Willebrand factor (vWF) levels. DDAVP is used as a hemostatic agent for the treatment of von Willebrand's disease. However, its cellular mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3275ad43bb1daf5f61212c28cf618b
https://archive-ouverte.unige.ch/unige:35180
https://archive-ouverte.unige.ch/unige:35180
Publikováno v:
Diabetes, Vol. 46, No 6 (1997) pp. 978-982
Proinsulin conversion to insulin occurs in secretory granules of pancreatic β-cells. This processing has been suggested to require both the endoproteases PC2 and PC3 with each cleaving at only one of the two sites linking the insulin A- and B-chains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b4225820c33c15d3e6730c21d40619
https://archive-ouverte.unige.ch/unige:9208
https://archive-ouverte.unige.ch/unige:9208
Publikováno v:
Diabetes, Vol. 44, No 9 (1995) pp. 1075-1080
The enzymology of proinsulin conversion was studied in COS cells by cotransfection of three species of proinsulin and each of three conversion endoproteases (furin, PC2, and PC3). In addition to the pairs of basic residues linking the B-chain to C-pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482e6661200572323ebbfa3d2d6bc38d
https://pubmed.ncbi.nlm.nih.gov/7657031
https://pubmed.ncbi.nlm.nih.gov/7657031