Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jocelyne Boulay"'
Autor:
Michal Sobecki, Charbel Souaid, Jocelyne Boulay, Vincent Guerineau, Daan Noordermeer, Laure Crabbe
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2891-2903.e5 (2018)
Summary: Mapping the binding sites of DNA- or chromatin-interacting proteins is essential to understanding biological processes. DNA adenine methyltransferase identification (DamID) has emerged as a comprehensive method to map genome-wide occupancy o
Externí odkaz:
https://doaj.org/article/5f19ab6ad3564970a23566bcc4c736d9
Autor:
Laura Cerchia, Frédéric Ducongé, Carine Pestourie, Jocelyne Boulay, Youssef Aissouni, Karine Gombert, Bertrand Tavitian, Vittorio de Franciscis, Domenico Libri
Publikováno v:
PLoS Biology, Vol 3, Iss 4, p e123 (2005)
Targeting large transmembrane molecules, including receptor tyrosine kinases, is a major pharmacological challenge. Specific oligonucleotide ligands (aptamers) can be generated for a variety of targets through the iterative evolution of a random pool
Externí odkaz:
https://doaj.org/article/ead8e11ade264496bfc22f633e942105
Autor:
Jocelyne Boulay, Domenico Libri, Tito Candelli, Drice Challal, Jessie Colin, Odil Porrua, Jean‐Baptiste Briand
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2018, ⟨10.15252/embj.201797490⟩
EMBO Journal, 2018, ⟨10.15252/embj.201797490⟩
EMBO Journal, EMBO Press, 2018, ⟨10.15252/embj.201797490⟩
EMBO Journal, 2018, ⟨10.15252/embj.201797490⟩
International audience; Transcription termination delimits transcription units but also plays important roles in limiting pervasive transcription. We have previously shown that transcription termination occurs when elongating RNA polymerase II (RNAPI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cdbfa56754cf903f803cb95c5810ba
https://doi.org/10.15252/embj.201797490
https://doi.org/10.15252/embj.201797490
Autor:
Jessie Colin, Lars M. Steinmetz, Domenico Libri, Jocelyne Boulay, Odil Porrua, François Lacroute, Chenchen Zhu, Tito Candelli
Publikováno v:
Molecular Cell. 56:667-680
Widely transcribed compact genomes must cope with the major challenge of frequent overlapping or concurrent transcription events. Efficient and timely transcription termination is crucial to control pervasive transcription and prevent transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9e9ef091524e52eca3f7a089eea34c
https://doi.org/10.1016/j.molcel.2014.10.026
https://doi.org/10.1016/j.molcel.2014.10.026
Autor:
Richard Štefl, Jocelyne Boulay, Karel Kubíček, Yves D'Aubenton‐Carafa, Rajani Kanth Gudipati, Domenico Libri, Fruzsina Hobor, Odil Porrua
Publikováno v:
The EMBO Journal. 31:3935-3948
The Nrd1-Nab3-Sen1 (NNS) complex pathway is responsible for transcription termination of cryptic unstable transcripts and sn/snoRNAs. The NNS complex recognizes short motifs on the nascent RNA, but the presence of these sequences alone is not suffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c229be4799511ea12e37e91a8138cc
https://doi.org/10.1038/emboj.2012.237
https://doi.org/10.1038/emboj.2012.237
Phosphorylation of the RNA polymerase II C-terminal domain dictates transcription termination choice
Publikováno v:
Nature Structural & Molecular Biology. 15:786-794
Cryptic unstable transcripts (CUTs) are short, 300-600-nucleotide (nt) RNA polymerase II transcripts that are rapidly degraded by the nuclear RNA exosome in yeast. CUTs are widespread and probably represent the largest share of hidden transcription i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10097e1ab276969e11413489f3b3fe38
https://doi.org/10.1038/nsmb.1460
https://doi.org/10.1038/nsmb.1460
Autor:
Domenico Libri, Mathieu Rougemaille, Elena Kisseleva-Romanova, Jocelyne Boulay, Marilyne Thiebaut
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2006, 23 (6), pp.853-64. ⟨10.1016/j.molcel.2006.07.029⟩
Molecular Cell, Elsevier, 2006, 23 (6), pp.853-64. ⟨10.1016/j.molcel.2006.07.029⟩
Cryptic unstable transcripts (CUTs) are widely distributed in the genome of S. cerevisiae. These RNAs generally derive from nonannotated regions of the genome and are degraded rapidly and efficiently by the nuclear exosome via a pathway that involves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981d5e2fd8945d77208feb694b09399b
https://doi.org/10.1016/j.molcel.2006.07.029
https://doi.org/10.1016/j.molcel.2006.07.029
Autor:
Jocelyne Boulay, Domenico Libri, Françoise Wyers, Béatrice Regnault, Mathieu Rougemaille, Frédéric Devaux, Abdelkader Namane, Jean-Claude Rousselle, Gwenael Badis, Bertrand Séraphin, Marie-Elisabeth Dufour, Alain Jacquier
Publikováno v:
Cell. 121:725-737
SummarySince detection of an RNA molecule is the major criterion to define transcriptional activity, the fraction of the genome that is expressed is generally considered to parallel the complexity of the transcriptome. We show here that several suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8742115dbe8a7bdf6f558b886a47de05
https://doi.org/10.1016/j.cell.2005.04.030
https://doi.org/10.1016/j.cell.2005.04.030
Autor:
Jessie Colin, Jocelyne Boulay, Torben Heick Jensen, Jens Raabjerg Olesen, Michael Weyler, Domenico Libri
Publikováno v:
Jensen, T H, Boulay, J, Olesen, J R, Colin, J, Weyler, M & Libri, D 2004, ' Modulation of transcription affects mRNP quality ', Mol. Cell., vol. 16, pp. 235-244 .
Aarhus University
Aarhus University
Cotranscriptional loading of proteins onto nascent transcripts contributes to the formation of messenger ribonucleoprotein particles (mRNPs) competent for nuclear export. The transcription machinery is believed to play a pivotal role in mRNP assembly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e51cdae51df65c5eb23cb83e727650f
https://doi.org/10.1016/j.molcel.2004.09.019
https://doi.org/10.1016/j.molcel.2004.09.019
Publikováno v:
Thomsen, R, Libri, D, Boulay, J, Rosbash, M & Jensen, T H 2003, ' Localization of nuclear retained mRNAs in Saccharomyces cerevisiae ', RNA, vol. 9, pp. 1049-1057 . https://doi.org/10.1261/rna.5170303
In the yeast Saccharomyces cerevisiae, a common conditional phenotype associated with deletion or mutation of genes encoding mRNA export factors is the rapid accumulation of mRNAs in intranuclear foci, suggested to be near transcription sites. The nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92299a29d1087509cf11d5c747a03001
https://doi.org/10.1261/rna.5170303
https://doi.org/10.1261/rna.5170303