Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jocelyn Y. Bullock"'
Autor:
Richard L.M. Faull, Stephen B. Hladky, Jocelyn Y. Bullock, Hasini C. Wijesuriya, Margery A. Barrand
Publikováno v:
Brain Research. 1358:228-238
Multidrug efflux transporters of the ATP-Binding cassette (ABC) family, P-glycoprotein (Pgp), multidrug-resistance associated protein 4 (MRP4) and breast cancer resistance protein (BCRP), located on endothelial cells lining brain vasculature play imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6561a49b1d38b0a56fbdd737db5fbe
https://doi.org/10.1016/j.brainres.2010.08.034
https://doi.org/10.1016/j.brainres.2010.08.034
Autor:
Richard L.M. Faull, Henry J. Waldvogel, Beth J. Synek, W.M.C. van Roon-Mom, Jocelyn Y. Bullock, Maurice A. Curtis
Publikováno v:
Cell and Tissue Banking. 9:169-179
To further understand the neuroanatomy, neurochemistry and neuropathology of the normal and diseased human brain, it is essential to have access to human brain tissue where the biological and chemical nature of the tissue is optimally preserved. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae87bd1fb10ed83924542392020eb75
https://doi.org/10.1007/s10561-008-9068-1
https://doi.org/10.1007/s10561-008-9068-1
Autor:
Douglas Macdonald, Wanzhao Liu, Kathryn Chase, Neil Aronin, Phillip D. Zamore, Lori A. Kennington, Richard L.M. Faull, Edith L. Pfister, Jean Paul G. Vonsattel, Marian DiFiglia, Joanna P Chaurette, Jocelyn Y. Bullock
Publikováno v:
Journal of Huntington's disease. 2(4)
Background Huntington's disease is caused by expansion of CAG trinucleotide repeats in the first exon of the huntingtin gene, which is essential for both development and neurogenesis. Huntington's disease is autosomal dominant. The normal allele cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b367a55437ef3e313e0437ab6613fbb9
https://pubmed.ncbi.nlm.nih.gov/25062733
https://pubmed.ncbi.nlm.nih.gov/25062733
Autor:
Jocelyn Y. Bullock, Richard L.M. Faull, N.J Butterworth, Donald R. Love, Mike Dragunow, Liam Williams
Publikováno v:
Neuroscience. 87:49-53
Recent studies using DNA fragmentation assays suggest a role for apoptosis in cell death in Huntington's disease. In this study, we investigated the relationship between the degree of DNA fragmentation and the number of trinucleotide (CAG) repeats of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204e66029d1fb9e1188a6dd18fa12695
https://doi.org/10.1016/s0306-4522(98)00129-8
https://doi.org/10.1016/s0306-4522(98)00129-8
Autor:
Richard L.M. Faull, Edward W. Mee, Beth J. Synek, Michelle Glass, E. B. Walker, Jocelyn Y. Bullock, Mike Dragunow, Karl L.R. Jansen
Publikováno v:
Brain research. 710(1-2)
Using quantitative receptor autoradiographic methods we have examined A1 adenosine receptors, adenosine uptake sites, benzodiazepine receptors, NMDA, AMPA, and kainic acid receptors in temporal lobes removed from patients suffering from complex parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2085cfd5938bedf5fc34222d1870fc87
https://pubmed.ncbi.nlm.nih.gov/8963679
https://pubmed.ncbi.nlm.nih.gov/8963679
Autor:
Stefano Patassini, Jocelyn Y. Bullock, J.T. den Dunnen, Menno H. Schut, R Faull, Henry J. Waldvogel, Eric H. Kim, Gjb van Ommen, Wmc van Roon-Mom, Barry A. Pepers
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 83:A7.3-A8
Huntington9s disease (HD) is an autosomal dominant neurodegenerative disease caused by elongation of a CAG-repeat within the first exon of the huntingtin gene. This mutation leads to a toxic gain-of-function of the huntingtin protein (htt). The exact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a571d5d234580e4b13e1ecca354ba90f
https://doi.org/10.1136/jnnp-2012-303524.23
https://doi.org/10.1136/jnnp-2012-303524.23
Autor:
Jocelyn Y. Bullock, Richard Faull, J.W. Villiger, Mike Dragunow, M.N. Williams, Henry J. Waldvogel, Karl L.R. Jansen
Publisher Summary This chapter focuses on receptors in human spinal cord. The distribution of benzodiazepine/GABAA receptors in the human spinal cord demonstrates that these receptors are distributed in a consistently similar fashion in the gray matt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851aa7dad311b4278ac7d7207f8d062d
https://doi.org/10.1016/b978-0-12-490830-7.50014-x
https://doi.org/10.1016/b978-0-12-490830-7.50014-x
Publikováno v:
Clinical Pharmacology & Therapeutics. 26:209-212
A recent publication suggested that antinuclear antibodies (ANA) occur in up to one third of patients treated with the hypotensive drug prazosin (Minipress). We have examined a large group of hypertensive patients and found ANA in 9.7% of 145 patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0b1472ef4b3885c034777230735b24
https://doi.org/10.1002/cpt1979262209
https://doi.org/10.1002/cpt1979262209
Publikováno v:
Journal of Urology. 118:604-606
The incidence of 7 different autoantibodies was determined in 904 men 3 months to 6 years after vasectomy operations and in 700 control subjects. There was no clinically significant increase in autoantibodies in the vasectomized group nor was any aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c8d425d54b636b0aa299cd5439cf2d
https://doi.org/10.1016/s0022-5347(17)58118-5
https://doi.org/10.1016/s0022-5347(17)58118-5
Publikováno v:
Clinical pharmacology and therapeutics. 31(5)
It has recently been reported that the Beta-adrenergic receptor-blocker acebutolol accelerates the development of antinuclear antibodies (ANAs) in hypertensive patients. We examined data from over 1500 hypertensive patients to determine whether this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b17554f08fc3e92dc52ae2ae9d24c42
https://pubmed.ncbi.nlm.nih.gov/6122525
https://pubmed.ncbi.nlm.nih.gov/6122525