Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Jocelyn T. Kim"'
Autor:
Yan-Ruide Li, Zachary Spencer Dunn, Gustavo Garcia, Camille Carmona, Yang Zhou, Derek Lee, Jiaji Yu, Jie Huang, Jocelyn T. Kim, Vaithilingaraja Arumugaswami, Pin Wang, Lili Yang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Background New COVID-19 treatments are desperately needed as case numbers continue to rise and emergent strains threaten vaccine efficacy. Cell therapy has revolutionized cancer treatment and holds much promise in combatting infectious disea
Externí odkaz:
https://doaj.org/article/74aabd5ed65c4d0f9920f86e4f4d975d
Autor:
Jocelyn T. Kim, Tian-Hao Zhang, Camille Carmona, Bryanna Lee, Christopher S. Seet, Matthew Kostelny, Nisarg Shah, Hongying Chen, Kylie Farrell, Mohamed S. A. Soliman, Melanie Dimapasoc, Michelle Sinani, Kenia Yazmin Reyna Blanco, David Bojorquez, Hong Jiang, Yuan Shi, Yushen Du, Natalia L. Komarova, Dominik Wodarz, Paul A. Wender, Matthew D. Marsden, Ren Sun, Jerome A. Zack
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Here, Kim et al. describe a new kick and kill strategy utilizing a single administration of a protein kinase C modulator and latency reversing agent in combination with injections of allogeneic peripheral blood natural killer cells diminishes the HIV
Externí odkaz:
https://doaj.org/article/7b9b98b368d54eccabea67b1cb3df389
Autor:
Jocelyn T. Kim, Jerome A. Zack
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
NK cells are an important subset of innate immune effectors with antiviral activity. However, NK cell development and immune responses in different tissues during acute and chronic HIV infection in vivo have been difficult to study due to the impaire
Externí odkaz:
https://doaj.org/article/3b383a5a35454641b4aaa2b8ad355bba
Publikováno v:
Microorganisms, Vol 11, Iss 8, p 1984 (2023)
Human immunodeficiency virus (HIV) has infected millions of people worldwide and continues to be a major global health problem. Scientists required a small animal model to study HIV pathogenesis and immune responses. To this end, humanized mice were
Externí odkaz:
https://doaj.org/article/7f62f6664655406d9e17bfa9698c6b64
Autor:
Lars Pache, Matthew D. Marsden, Peter Teriete, Alex J. Portillo, Dominik Heimann, Jocelyn T. Kim, Mohamed S.A. Soliman, Melanie Dimapasoc, Camille Carmona, Maria Celeridad, Adam M. Spivak, Vicente Planelles, Nicholas D.P. Cosford, Jerome A. Zack, Sumit K. Chanda
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100037- (2020)
Summary: “Shock and kill” strategies focus on purging the latent HIV-1 reservoir by treating infected individuals with therapeutics that activate the latent virus and subsequently eliminating infected cells. We have previously reported that induc
Externí odkaz:
https://doaj.org/article/844b2284d4654ae7b526e217e79fb151
Autor:
Jose A. Moran, Alok Ranjan, Rami Hourani, Jocelyn T. Kim, Paul A. Wender, Jerome A. Zack, Matthew D. Marsden
Publikováno v:
Virology. 581:8-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4137b4194e997f92cef3e1690347f184
https://doi.org/10.1016/j.virol.2023.02.009
https://doi.org/10.1016/j.virol.2023.02.009
Autor:
Pavlo A. Nesterenko, Jami McLaughlin, Brandon L. Tsai, Giselle Burton Sojo, Donghui Cheng, Daniel Zhao, Zhiyuan Mao, Nathanael J. Bangayan, Matthew B. Obusan, Yapeng Su, Rachel H. Ng, William Chour, Jingyi Xie, Yan-Ruide Li, Derek Lee, Miyako Noguchi, Camille Carmona, John W. Phillips, Jocelyn T. Kim, Lili Yang, James R. Heath, Paul C. Boutros, Owen N. Witte
Publikováno v:
Cell Reports
Cross-reactivity and direct killing of target cells remain underexplored for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-specific CD8+ T cells. Isolation of T cell receptors (TCRs) and overexpression in allogeneic cells allows for ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab3372958a954daff44b4d324559063
https://resolver.caltech.edu/CaltechAUTHORS:20211210-240628000
https://resolver.caltech.edu/CaltechAUTHORS:20211210-240628000
Autor:
Michelle Phan-Tang, Augustine Chung, Rajan Saggar, Jeffrey D. Goldstein, Negar Khanlou, Daniel Hoesterey, Steven M. Dubinett, Kristin Schwab, Raymond J. Lim, Tisha Wang, John A. Belperio, Camelia Dumitras, Ramin Salehi-Rad, Jocelyn T. Kim, Oladunni Adeyiga, Sepehr Hamidi
Publikováno v:
Open Forum Infectious Diseases
Open forum infectious diseases, vol 7, iss 11
Open forum infectious diseases, vol 7, iss 11
Background Interleukin-6 blockade (IL-6) has become a focus of therapeutic investigation for the coronavirus disease 2019 (COVID-19). Methods We report a case of a 34-year-old with COVID-19 pneumonia receiving an IL-6 receptor antagonist (IL-6Ra) who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cfa150e1e87fb6945ee4a3fa2bde96
http://europepmc.org/articles/PMC7543619
http://europepmc.org/articles/PMC7543619
Autor:
Peter Teriete, Matthew D. Marsden, Jerome A. Zack, Vicente Planelles, Camille Carmona, Sumit K. Chanda, Dominik Heimann, Adam M. Spivak, Maria Celeridad, Nicholas D. P. Cosford, Lars Pache, Jocelyn T. Kim, Mohamed S.A. Soliman, Alex J. Portillo, Melanie Dimapasoc
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100037-(2020)
Cell Reports Medicine
Cell Reports Medicine
Summary “Shock and kill” strategies focus on purging the latent HIV-1 reservoir by treating infected individuals with therapeutics that activate the latent virus and subsequently eliminating infected cells. We have previously reported that induct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e625a17d3aebe525d17d95aacb59e75
http://www.sciencedirect.com/science/article/pii/S2666379120300495
http://www.sciencedirect.com/science/article/pii/S2666379120300495
Autor:
Ren Sun, Yushen Du, Xiaomeng Wu, Tian-hao Zhang, Akira J. Shimizu, Adam J. Schrier, Jocelyn T. Kim, Paul A. Wender, Melanie Dimapasoc, Mohamed S.A. Soliman, Jerome A. Zack, Matthew D. Marsden
Publikováno v:
Cell Reports Medicine
Summary HIV latency prevents cure of infection with antiretroviral therapy (ART) alone. One strategy for eliminating latently infected cells involves the induction of viral protein expression via latency-reversing agents (LRAs), allowing killing of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9abf7ba49db2195eb9019d5b27e8f2d
https://pubmed.ncbi.nlm.nih.gov/33377133
https://pubmed.ncbi.nlm.nih.gov/33377133