Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jocelyn Stockwell"'
Autor:
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
Publikováno v:
iScience, Vol 19, Iss , Pp 1114-1132 (2019)
Summary: Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-ba
Externí odkaz:
https://doaj.org/article/c6301e8c20a347908830d745496bf253
Publikováno v:
Molecules, Vol 22, Iss 4, p 676 (2017)
The inhibitory adenosine A1 receptor (A1R) and excitatory A2A receptor (A2AR) are predominantly expressed in the brain. Whereas the A2AR has been implicated in normal aging and enhancing neurotoxicity in multiple neurodegenerative diseases, the inhib
Externí odkaz:
https://doaj.org/article/b2771730be6a465dac5ffba5f3ab5a04
Autor:
Nichollas E. Scott, Bhanu Prasad, Mara Zilocchi, Francisco S. Cayabyab, Qingzhou Zhang, Leonard J. Foster, Jocelyn Stockwell, Alex Rajput, Hiroyuki Aoki, Yasushi Okazaki, Ramy H. Malty, James Vlasblom, Mohan Babu, Sadhna Phanse, Larissa Hoell, Matthew Jessulat, Zoran Minic, Eleonora Lamantea, Alla Gagarinova, Barbara Garavaglia, Mohamed Taha Moutaoufik, Maria Gagarinova, Shahreen Amin, Florian Goebels, Kei Murayama, Kirsten Broderick, Gary D. Bader, Gabriel Musso
Publikováno v:
iScience, Vol 19, Iss, Pp 1114-1132 (2019)
iScience
iScience
Summary Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f9d4f6ef65c96ea044d1c087ba5a27
https://hdl.handle.net/10281/417319
https://hdl.handle.net/10281/417319
Autor:
Cherry Xiong, Jocelyn Stockwell, Wolfgang Walz, Cassandra Pancyr, Zhicheng Chen, Francisco S. Cayabyab
Publikováno v:
Journal of Neuroscience. 34:9621-9643
Activation of presynaptic adenosine A1 receptors (A1Rs) causes substantial synaptic depression during hypoxia/cerebral ischemia, but postsynaptic actions of A1Rs are less clear. We found that A1Rs and GluA2-containing AMPA receptors (AMPARs) form sta
Publikováno v:
Neurochemical research. 41(5)
Aging causes multiple changes in the mammalian brain, including changes in synaptic signaling. Previous reports have shown increased extracellular adenosine in the aging brain, and we recently reported that activation of adenosine A1 receptors (A1Rs)
Publikováno v:
Chemical biologydrug design. 83(5)
For decades, biomedical and pharmaceutical researchers have worked to devise new and more effective therapeutics to treat diseases affecting the central nervous system. The blood-brain barrier effectively protects the brain, but poses a profound chal
Publikováno v:
Neuropharmacology. :254-265
Adenosine signaling via A1 receptor (A1R) and A2A receptor (A2AR) has shown promise in revealing potential targets for neuroprotection in cerebral ischemia. We recently showed a novel mechanism by which A1R activation with N6-cyclopentyl adenosine (C