Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jocelyn Rivera-Ortiz"'
Autor:
Jocelyn Rivera-Ortiz, Jessalyn Pla-Tenorio, Myrella L. Cruz, Krystal Colon, Jaileene Perez-Morales, Julio A. Rodriguez, Jorge Martinez-Sicari, Richard J. Noel
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Combination antiretroviral therapy (cART) targets viral replication, but early viral protein production by astrocytes may still occur and contribute to the progression of HIV-1 associated neurocognitive disorders and secondary complications seen in p
Externí odkaz:
https://doaj.org/article/267a0a22d33e47db9920e0cb21afb3f1
Autor:
Ian Tietjen, Cole Schonhofer, Amanda Sciorillo, Maya E. Naidu, Zahra Haq, Toshitha Kannan, Andrew V. Kossenkov, Jocelyn Rivera-Ortiz, Karam Mounzer, Colin Hart, Kwasi Gyampoh, Zhe Yuan, Karren D. Beattie, Topul Rali, Kristy Shuda McGuire, Rohan A. Davis, Luis J. Montaner
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Despite effective combination antiretroviral therapy (cART), people living with HIV (PLWH) continue to harbor replication-competent and transcriptionally active virus in infected cells, which in turn can lead to ongoing viral antigen production, chro
Autor:
Peter Imming, Marianne Harris, Zabrina L. Brumme, Mohamed Abdel-Mohsen, Kerstin Andrae-Marobela, Natalie N. Kinloch, Karam Mounzer, Leila B. Giron, Ian Tietjen, Silven Read, Simone Wappler, Toshitha Kannan, Mark A. Brockman, Luis J. Montaner, Aniqa Shahid, Khumoekae Richard, Andrew V. Kossenkov, Cole Schonhofer, Ruth Feilcke, Jocelyn Rivera-Ortiz
Publikováno v:
J Biol Chem
A sterilizing or functional cure for HIV is currently precluded by resting CD4(+) T cells that harbor latent but replication-competent provirus. The “shock-and-kill” pharmacological ap-proach aims to reactivate provirus expression in the presence