Zobrazeno 1 - 2
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pro vyhledávání: '"Jocelyn Pena"'
A new vulnerability to BET inhibition due to enhanced autophagy in BRCA2 deficient pancreatic cancer
Autor:
EunJung Lee, Suyakarn Archasappawat, Keely Ji, Jocelyn Pena, Virneliz Fernandez-Vega, Ritika Gangaraju, Nitin Sai Beesabathuni, Martin Jean Kim, Qi Tian, Priya S. Shah, Louis Scampavia, Timothy P. Spicer, Chang-Il Hwang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-11 (2023)
Abstract Pancreatic cancer is one of the deadliest diseases in human malignancies. Among total pancreatic cancer patients, ~10% of patients are categorized as familial pancreatic cancer (FPC) patients, carrying germline mutations of the genes involve
Externí odkaz:
https://doaj.org/article/9724ab7f7f6f42e8a12f619770e9bc57
Double-stranded DNA (dsDNA) in the cytoplasm of eukaryotic cells is abnormal and typically indicates the presence of pathogens or mislocalized self-DNA. Multiple sensors detect cytosolic dsDNA and trigger robust immune responses via activation of typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::468a4cc33f899e5473188125e628ec64
https://doi.org/10.21203/rs.3.rs-2264736/v1
https://doi.org/10.21203/rs.3.rs-2264736/v1