Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Jocelyn M. Baldwin"'
1
Characterisation of the DAACS Family Escherichia coli Glutamate/Aspartate-Proton Symporter GltP Using Computational, Chemical, Biochemical and Biophysical Methods
Autor: Li Jiao, Stephen A. Baldwin, Jocelyn M. Baldwin, Fouzia Ismat, David Sharples, Simon G. Patching, Moazur Rahman
Publikováno v: The Journal of Membrane Biology. 250:145-162
Escherichia coli glutamate/aspartate-proton symporter GltP is a member of the Dicarboxylate/Amino Acid:Cation Symporter family of secondary active transport proteins. A range of computational, chemical, biochemical and biophysical methods characteris
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cab0f46bf3a502cc84a81bcacd14bb4
https://doi.org/10.1007/s00232-016-9942-x
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2
The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29
Autor: Carol E. Cass, Stephen A. Baldwin, Sylvia Y.M. Yao, James D. Young, Jocelyn M. Baldwin
Publikováno v: Molecular Aspects of Medicine; Vol 34
Nucleoside transport in humans is mediated by members of two unrelated protein families, the SLC28 family of cation-linked concentrative nucleoside transporters (CNTs) and the SLC29 family of energy-independent, equilibrative nucleoside transporters
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d65f49278c44a48ef1690089869d824
https://doi.org/10.1016/j.mam.2012.05.007
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3
Use of molecular modelling to probe the mechanism of the nucleoside transporter NupG
Autor: Hamidreza Vaziri, David G. Adams, Jocelyn M. Baldwin, James D. Young, Vincent L. G. Postis, Stephen A. Baldwin
Publikováno v: Molecular Membrane Biology; Vol 30
Molecular Membrane Biology
Nucleosides play key roles in biology as precursors for salvage pathways of nucleotide synthesis. Prokaryotes import nucleosides across the cytoplasmic membrane by proton- or sodium-driven transporters belonging to the Concentrative Nucleoside Transp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6beb437dd2d933ddc6c60c27dac76237
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4
Allantoin transport protein, PucI, from Bacillus subtilis: evolutionary relationships, amplified expression, activity and specificity
Autor: Simon G. Patching, Ekaterina Ivanova, Stephen A. Baldwin, Pikyee Ma, David Sharples, Peter J. F. Henderson, Jocelyn M. Baldwin
Publikováno v: Microbiology
Microbiology, Microbiology Society, 2016, 162 (5), pp.823-836. ⟨10.1099/mic.0.000266⟩
This work reports the evolutionary relationships, amplified expression, functional characterization and purification of the putative allantoin transport protein, PucI, from Bacillus subtilis. Sequence alignments and phylogenetic analysis confirmed cl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee305dd1acf706b79bc0f9bb47f4ae2
https://hal.archives-ouvertes.fr/hal-02562827
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5
Role of Transmembrane Domain 8 in Substrate Selectivity and Translocation of SteT, a Member of the L-Amino Acid Transporter (LAT) Family
Autor: Stephen A. Baldwin, Jocelyn M. Baldwin, Matthias Quick, Antonio Zorzano, Merce Ratera, César del Rio, Paola Bartoccioni, Manuel Palacín, Lukasz Kowalczyk, José Luis Vázquez-Ibar
Publikováno v: Journal of Biological Chemistry; Vol 285
System l-amino acid transporters (LAT) belong to the amino acid, polyamine, and organic cation superfamily of transporters and include the light subunits of heteromeric amino acid transporters and prokaryotic homologues. Cysteine reactivity of SteT (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf7d40343f946ca749f3ab9745f61d6
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6
Mutations in theArabidopsisPeroxisomal ABC Transporter COMATOSE Allow Differentiation between Multiple Functions In Planta: Insights from an Allelic Series
Autor: Heike Schmuths, Jocelyn M. Baldwin, Daniela Dietrich, Frederica L. Theodoulou, Stephen A. Baldwin, Alison Baker, Carine De Marcos Lousa, Michael J. Holdsworth
Publikováno v: Molecular Biology of the Cell. 20:530-543
COMATOSE (CTS), the Arabidopsis homologue of human Adrenoleukodystrophy protein (ALDP), is required for import of substrates for peroxisomal β-oxidation. A new allelic series and a homology model based on the bacterial ABC transporter, Sav1866, prov
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b6d8691ed855db1f099cfef21d4a1a
https://doi.org/10.1091/mbc.e08-07-0745
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7
A Rare Mutation in ABCC8/SUR1 Leading to Altered ATP-Sensitive K+ Channel Activity and β-Cell Glucose Sensing Is Associated With Type 2 Diabetes in Adults
Autor: Jean François Gautier, Tarvinder K. Taneja, Philippe Froguel, Guy A. Rutter, Andrei I. Tarasov, Martine Vaxillaire, Jocelyn M. Baldwin, Guillaume Charpentier, Stephen A. Baldwin, Jean-Pierre Riveline, Tamara J. Nicolson
Publikováno v: Diabetes. 57:1595-1604
OBJECTIVE— ATP-sensitive K+ channels (KATP channels) link glucose metabolism to the electrical activity of the pancreatic β-cell to regulate insulin secretion. Mutations in either the Kir6.2 or sulfonylurea receptor (SUR) 1 subunit of the channel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97763d4083f2800921f01c76c4ced2d2
https://doi.org/10.2337/db07-1547
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8
Relative substrate affinities of wild-type and mutant forms of theEscherichia colisugar transporter GalP determined by solid-state NMR
Autor: Georgios Psakis, Stephen A. Baldwin, David A. Middleton, Peter J. F. Henderson, Jocelyn M. Baldwin, Simon G. Patching
Publikováno v: Molecular Membrane Biology. 25:474-484
Solid-state nuclear magnetic resonance (SSNMR) spectroscopy is used for the first time to examine the relative substrate-binding affinities of mutant forms of the Escherichia coli sugar transporter GalP in membrane preparations. The SSNMR method of (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c9ba8d19fef1a9c032c13577a8d366
https://doi.org/10.1080/09687680802371963
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9
Plant Peroxisomal ABC Transporters: Flexible and Unusual
Autor: Alison Baker, Stephen A. Baldwin, Jocelyn M. Baldwin, Frederica L. Theodoulou
Publikováno v: Signaling and Communication in Plants ISBN: 9783319065106
ABC transporters of subfamily D mediate import of substrates for β-oxidation into peroxisomes. Whilst mammals possess three peroxisomal ABCD proteins which homodimerise to form transporters with distinct substrate specificities, Baker’s yeast has
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478d39293bf7285a841e6578d8ad3ca2
https://doi.org/10.1007/978-3-319-06511-3_6
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10
Insights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide Polymorphisms
Autor: Jocelyn M. Baldwin, Sébastien Roger, Lin-Hua Jiang, Stephen A. Baldwin
Publikováno v: Frontiers in Pharmacology, Vol 4 (2013)
Frontiers in Pharmacology
The mammalian P2X7 receptors (P2X7Rs), a member of the ionotropic P2X receptor family with distinctive functional properties, play an important part in mediating extracellular ATP signaling in health and disease. A clear delineation of the molecular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab9206cb5dfc2397853ee47de80fba8
https://doi.org/10.3389/fphar.2013.00055
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