Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jocelyn J. Lippman-Bell"'
Autor:
Evan C. Rosenberg, Jocelyn J. Lippman-Bell, Marcus Handy, Samantha S. Soldan, Sanjay Rakhade, Cristina Hilario-Gomez, Kaitlyn Folweiler, Leah Jacobs, Frances E. Jensen
Publikováno v:
Neurobiology of Disease, Vol 116, Iss , Pp 120-130 (2018)
Neonatal seizures disrupt normal synaptic maturation and often lead to later-life epilepsy and cognitive deficits. During early life, the brain exhibits heightened synaptic plasticity, in part due to a developmental overabundance of CaV1.2 L-type vol
Externí odkaz:
https://doaj.org/article/52d81e84660a48ee9545b14b1a37b01b
Autor:
Hongyu Sun, Anne E. Takesian, Ting Ting Wang, Jocelyn J. Lippman-Bell, Takao K. Hensch, Frances E. Jensen
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2533-2540 (2018)
Heightened neural excitability in infancy and childhood results in increased susceptibility to seizures. Such early-life seizures are associated with language deficits and autism that can result from aberrant development of the auditory cortex. Here,
Externí odkaz:
https://doaj.org/article/59fd556c56dd4897814aad293b88d367
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30959dc566562e125cea92a88fca6702
https://doi.org/10.1096/fasebj.2021.35.s1.02788
https://doi.org/10.1096/fasebj.2021.35.s1.02788
Publikováno v:
Molecular and cellular neurosciences. 113
Cognitive comorbidities often follow early-life seizures (ELS), especially in the setting of autism and other neurodevelopmental syndromes. However, there is an incomplete understanding of whether neuronal and synaptic development are concomitantly d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27286c9d2248df5975c9af6f57412dc1
https://pubmed.ncbi.nlm.nih.gov/34015497
https://pubmed.ncbi.nlm.nih.gov/34015497
Autor:
Frances E. Jensen, Leah M. Jacobs, Sanjay N. Rakhade, Cristina Hilario-Gomez, Samantha S. Soldan, Evan C. Rosenberg, Jocelyn J. Lippman-Bell, Kaitlyn Folweiler, Marcus Handy
Publikováno v:
Neurobiology of Disease, Vol 116, Iss, Pp 120-130 (2018)
Neonatal seizures disrupt normal synaptic maturation and often lead to later-life epilepsy and cognitive deficits. During early life, the brain exhibits heightened synaptic plasticity, in part due to a developmental overabundance of CaV1.2 L-type vol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f152385b08349a5b0da899bd31e31e
https://pubmed.ncbi.nlm.nih.gov/29738885
https://pubmed.ncbi.nlm.nih.gov/29738885
Calcium (Ca2+)-mediated 4 signaling pathways are critical to synaptic plasticity. In adults, the NMDA glutamate receptor (NMDAR) represents a major route for activity-dependent synaptic Ca2+ entry. However, during neonatal development, when synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c973610fd24055b16d0172e3b1e299d9
https://europepmc.org/articles/PMC5056834/
https://europepmc.org/articles/PMC5056834/
Autor:
Jocelyn J. Lippman-Bell, Anne E. Takesian, Ting Ting Wang, Takao K. Hensch, Hongyu Sun, Frances E. Jensen
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2533-2540 (2018)
Cell reports
Cell reports
SUMMARY Heightened neural excitability in infancy and childhood results in increased susceptibility to seizures. Such early-life seizures are associated with language deficits and autism that can result from aberrant development of the auditory corte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2b6716d1868beab4e186ccac75887b
https://pubmed.ncbi.nlm.nih.gov/30568558
https://pubmed.ncbi.nlm.nih.gov/30568558
Publikováno v:
Neuron Glia Biology. 6:193-200
In the cerebellum, lamellar Bergmann glial (BG) appendages wrap tightly around almost every Purkinje cell dendritic spine. The function of this glial ensheathment of spines is not entirely understood. The development of ensheathment begins near the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268e3b2ff1304fbfe83eda868db83dee
https://doi.org/10.1017/s1740925x10000165
https://doi.org/10.1017/s1740925x10000165
Autor:
Frances E. Jensen, Jocelyn J. Lippman-Bell, Annelise Joseph, Michele Jackson, Sanjay N. Rakhade, Makram Obeid, Peter M. Klein
Publikováno v:
Epilepsia. 54(11)
To determine whether AMPA receptor (AMPAR) antagonist NBQX can prevent early mammalian target of rapamycin (mTOR) pathway activation and long-term sequelae following neonatal seizures in rats, including later-life spontaneous recurrent seizures, CA3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cea992512232911d972bd189c3eef0
https://pubmed.ncbi.nlm.nih.gov/24117347
https://pubmed.ncbi.nlm.nih.gov/24117347
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(50)
Neonatal seizures can lead to epilepsy and long-term cognitive deficits in adulthood. Using a rodent model of the most common form of human neonatal seizures, hypoxia-induced seizures (HS), we aimed to determine whether these seizures modify long-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8deee9abf7271c85c6b380ae274f9d4
https://pubmed.ncbi.nlm.nih.gov/22171027
https://pubmed.ncbi.nlm.nih.gov/22171027