Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jocelyn F Chen"'
Autor:
Lizhen Wu, Jian Cao, Wesley L Cai, Sabine M Lang, John R Horton, Daniel J Jansen, Zongzhi Z Liu, Jocelyn F Chen, Meiling Zhang, Bryan T Mott, Katherine Pohida, Ganesha Rai, Stephen C Kales, Mark J Henderson, Xin Hu, Ajit Jadhav, David J Maloney, Anton Simeonov, Shu Zhu, Akiko Iwasaki, Matthew D Hall, Xiaodong Cheng, Gerald S Shadel, Qin Yan
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2006134 (2018)
Cyclic GMP-AMP (cGAMP) synthase (cGAS) stimulator of interferon genes (STING) senses pathogen-derived or abnormal self-DNA in the cytosol and triggers an innate immune defense against microbial infection and cancer. STING agonists induce both innate
Externí odkaz:
https://doaj.org/article/b82bd2d7d5a04000a7a64e580355ce3f
Autor:
Wesley L. Cai, Celeste B. Greer, Jocelyn F. Chen, Anna Arnal-Estapé, Jian Cao, Qin Yan, Don X. Nguyen
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Background Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the epigenomic alterat
Externí odkaz:
https://doaj.org/article/ab87df052f1042da9558ebcc14ccc2e6
Autor:
Wesley L Cai, Jocelyn F Chen, Huacui Chen, Emily Wingrove, Sarah J Kurley, Lok Hei Chan, Meiling Zhang, Anna Arnal-Estapé, Minghui Zhao, Amer Balabaki, Wenxue Li, Xufen Yu, Yali Dou, Yansheng Liu, Jian Jin, Thomas F Westbrook, Don Nguyen, Qin Yan
Metastatic breast cancer remains a major cause of cancer related deaths in women and there are few effective therapies against this advanced disease. Emerging evidence suggests that key steps of tumor progression and metastasis are controlled by reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::469ba91ae958a539a9dbb5fe47607b4b
https://doi.org/10.1101/2022.03.30.486357
https://doi.org/10.1101/2022.03.30.486357
Autor:
Meiling Zhang, Zongzhi Z. Liu, Keisuke Aoshima, Wesley L. Cai, Hongyin Sun, Tianrui Xu, Yangyi Zhang, Yongyan An, Jocelyn F. Chen, Lok Hei Chan, Asako Aoshima, Sabine M. Lang, Zhenwei Tang, Xuanlin Che, Yao Li, Sara J. Rutter, Veerle Bossuyt, Xiang Chen, Jon S. Morrow, Lajos Pusztai, David L. Rimm, Mingzhu Yin, Qin Yan
Publikováno v:
Sci Transl Med
Metastasis is the major cause of cancer-related deaths due to the lack of effective therapies. Emerging evidence suggests that certain epigenetic and transcriptional regulators drive cancer metastasis and could be targeted for metastasis treatment. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b969c03a480097e32208712f707c84f
https://doi.org/10.1126/scitranslmed.abf5473
https://doi.org/10.1126/scitranslmed.abf5473
Autor:
Jocelyn F. Chen, Qin Yan
Publikováno v:
Biochem J
Cancer metastasis remains a major clinical challenge for cancer treatment. It is therefore crucial to understand how cancer cells establish and maintain their metastatic traits. However, metastasis-specific genetic mutations have not been identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4d9ec62e8bf10a8bba0fd61d3e6de2
https://pubmed.ncbi.nlm.nih.gov/34520519
https://pubmed.ncbi.nlm.nih.gov/34520519
Autor:
Anna Arnal-Estapé, Don X. Nguyen, Qin Yan, Jocelyn F. Chen, Wesley L. Cai, Jian Cao, Celeste B. Greer
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)
Background Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the epigenomic alterations and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92682f71c04721ef9a0ac7fbde88d68
https://doi.org/10.1186/s12920-020-0695-0
https://doi.org/10.1186/s12920-020-0695-0
Autor:
Ajit Jadhav, Lizhen Wu, Daniel J. Jansen, Xin Hu, Mark J. Henderson, David J. Maloney, John R. Horton, Jian Cao, Stephen C. Kales, Bryan T. Mott, Anton Simeonov, Qin Yan, Shu Zhu, Wesley L. Cai, Gerald S. Shadel, Zongzhi Liu, Jocelyn F. Chen, Meiling Zhang, Xiaodong Cheng, Katherine Pohida, Ganesha Rai, Akiko Iwasaki, Sabine Lang, Matthew D. Hall
Publikováno v:
PLoS Biology
PLoS Biology, Vol 16, Iss 8, p e2006134 (2018)
PLoS Biology, Vol 16, Iss 8, p e2006134 (2018)
Cyclic GMP-AMP (cGAMP) synthase (cGAS) stimulator of interferon genes (STING) senses pathogen-derived or abnormal self-DNA in the cytosol and triggers an innate immune defense against microbial infection and cancer. STING agonists induce both innate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92ce627a76571c3862e1d1c95959892
https://pubmed.ncbi.nlm.nih.gov/30080846
https://pubmed.ncbi.nlm.nih.gov/30080846