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pro vyhledávání: '"Jocelyn E. Brown"'
Publikováno v:
Tetrahedron Letters. 56:3564-3566
The carbofunctionalization of 2-bromo-N-benzyl indole via lithium–bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields.
Publikováno v:
ChemInform. 46
Indole (I) undergoes a lithium-bromide exchange and subsequent nucleophilic addition to ketones and aldehydes to give the corresponding 2-functionalized derivatives.