Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jocelyn, Widagdo"'
Autor:
Odette Leiter, David Brici, Stephen J. Fletcher, Xuan Ling Hilary Yong, Jocelyn Widagdo, Nicholas Matigian, Adam B. Schroer, Gregor Bieri, Daniel G. Blackmore, Perry F. Bartlett, Victor Anggono, Saul A. Villeda, Tara L. Walker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The beneficial effects of physical activity on brain ageing are well recognised, with exerkines, factors that are secreted into the circulation in response to exercise, emerging as likely mediators of this response. However, the source and i
Externí odkaz:
https://doaj.org/article/d8e83ff214284a649830da1f3c2ec9ee
Autor:
Jing Zhi Anson Tan, Se Eun Jang, Ana Batallas-Borja, Nishita Bhembre, Mintu Chandra, Lingrui Zhang, Huimin Guo, Mitchell T. Ringuet, Jocelyn Widagdo, Brett M. Collins, Victor Anggono
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113460- (2023)
Summary: The recruitment of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors underlies the strengthening of neuronal connectivity during learning and memory. This process is triggered by N-methyl-D-aspartate (NMDA) rec
Externí odkaz:
https://doaj.org/article/4474e4516773492c91d72485b72ad7d7
Autor:
Jocelyn Widagdo, Saumya Udagedara, Nishita Bhembre, Jing Zhi Anson Tan, Lara Neureiter, Jie Huang, Victor Anggono, Mihwa Lee
Publikováno v:
Open Biology, Vol 12, Iss 9 (2022)
Splicing factor proline- and glutamine-rich (SFPQ) is a nuclear RNA-binding protein that is involved in a wide range of physiological processes including neuronal development and homeostasis. However, the mislocalization and cytoplasmic aggregation o
Externí odkaz:
https://doaj.org/article/a29d7e2ad7fb4ee6b2e6110bedc26be9
Autor:
Rowan A. W. Radford, Stephanie L. Rayner, Paulina Szwaja, Marco Morsch, Flora Cheng, Tianyi Zhu, Jocelyn Widagdo, Victor Anggono, Dean L. Pountney, Roger Chung, Albert Lee
Publikováno v:
Journal of Neurochemistry. 165:563-586
Publikováno v:
Seminars in Cell & Developmental Biology. 125:110-121
Activity-dependent gene expression and protein translation underlie the ability of neurons to dynamically adjust their synaptic strength in response to sensory experience and during learning. The emerging field of epitranscriptomics (RNA modification
Publikováno v:
Trends in Genetics. 38:325-332
Autor:
Jocelyn Widagdo, Ye Jin Chai, Margreet C. Ridder, Yu Qian Chau, Richard C. Johnson, Pankaj Sah, Richard L. Huganir, Victor Anggono
Publikováno v:
Cell Reports, Vol 10, Iss 5, Pp 783-795 (2015)
AMPA receptors (AMPARs) have recently been shown to undergo post-translational ubiquitination in mammalian neurons. However, the underlying molecular mechanisms are poorly understood and remain controversial. Here, we report that all four AMPAR subun
Externí odkaz:
https://doaj.org/article/58f93ae5adae47d188584b28a26bb7eb
Autor:
Andrew C. Marshall, Jerry Cummins, Simon Kobelke, Tianyi Zhu, Jocelyn Widagdo, Victor Anggono, Anthony Hyman, Archa H. Fox, Charles S. Bond, Mihwa Lee
Demixing of proteins and nucleic acids into condensed liquid phases is rapidly emerging as a ubiquitous mechanism underlying the complex spatiotemporal organisation of molecules within the cell. Long disordered regions of low sequence complexity (LCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::528dd6a3f6d6edeeee5ab8468903cea3
https://doi.org/10.1101/2022.11.30.518278
https://doi.org/10.1101/2022.11.30.518278
Publikováno v:
Aging cellREFERENCES.
The aged brain is associated with an inevitable decline in cognitive function and increased vulnerability to neurodegenerative disorders. Multiple molecular hallmarks have been associated with the aging nervous system through transcriptomics and prot
Autor:
Jocelyn, Widagdo, Saumya, Udagedara, Nishita, Bhembre, Jing Zhi Anson, Tan, Lara, Neureiter, Jie, Huang, Victor, Anggono, Mihwa, Lee
Publikováno v:
Open biology. 12(9)
Splicing factor proline- and glutamine-rich (SFPQ) is a nuclear RNA-binding protein that is involved in a wide range of physiological processes including neuronal development and homeostasis. However, the mislocalization and cytoplasmic aggregation o