Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jocelyn, Darby"'
Publikováno v:
Bio-Protocol, Vol 10, Iss 13 (2020)
This protocol provides a step-by-step method to create recombinant fluorescent fusion proteins that can be secreted from mammalian cell lines. This builds on many other recombinant protein and fluorescent protein techniques, but is among the first to
Externí odkaz:
https://doaj.org/article/a2c0e985d4e045c3b94fc857c1e8bf79
Autor:
Ruth Pye, Jocelyn Darby, Andrew S. Flies, Samantha Fox, Scott Carver, Jodie Elmer, Kate Swift, Carolyn Hogg, David Pemberton, Gregory Woods, A. Bruce Lyons
Publikováno v:
Wildlife Research. 48:701-712
Context Disease is increasingly becoming a driver of wildlife population declines and an extinction risk. Vaccines are one of the most successful health interventions in human history, but few have been tested for mitigating wildlife disease. The tra
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The absence of tumor necrosis factor (TNF) causes lethal infection by Leishmania major in normally resistant C57BL/6J (B6.WT) mice. The underlying pathogenic mechanism of this fatal disease has so far remained elusive. We found that B6.WT mice defici
Externí odkaz:
https://doaj.org/article/6605c751b7be4fbca61874fd1167b160
Autor:
Cesar Tovar, Amanda L Patchett, Vitna Kim, Richard Wilson, Jocelyn Darby, A Bruce Lyons, Gregory M Woods
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196469 (2018)
The Tasmanian devil (Sarcophilus harrisii), the largest extant carnivorous marsupial and endemic to Tasmania, is at the verge of extinction due to the emergence of a transmissible cancer known as devil facial tumour disease (DFTD). DFTD has spread ov
Externí odkaz:
https://doaj.org/article/939dc7a0dc22402f9c2b5a7390257c42
Autor:
Grace G Russell, Chiara Palmieri, Jocelyn Darby, Gary P. Morris, Nicholas M. Fountain-Jones, Ruth J. Pye, Andrew S. Flies
The wild Tasmanian devil (Sarchophilus harrisii) population has suffered a devastating decline due to two clonal transmissible cancers. Devil facial tumor 1 (DFT1) was first observed in 1996, followed by a second genetically distinct transmissible tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26bb792951ee1d34ecfce9496b406a76
https://doi.org/10.1101/2022.10.31.513798
https://doi.org/10.1101/2022.10.31.513798
Publikováno v:
Antibodies, Vol 4, Iss 1, Pp 1-10 (2014)
The phenotypical consequences of a combined deficiency of the Fas-Fas Ligand (FasL) and one or both Tumor Necrosis Factor (TNF) signaling pathways were investigated. Mice, which expressed a non-functional FasL suffered from a pathological accumulatio
Externí odkaz:
https://doaj.org/article/cc348d6e37d6467197cb59e03bab5841
Autor:
Shanshan, Hu, Cameron, Marshall, Jocelyn, Darby, Wei, Wei, Alan Bruce, Lyons, Heinrich, Körner
Publikováno v:
Frontiers in Immunology
The absence of tumor necrosis factor (TNF) causes lethal infection by Leishmania major in normally resistant C57BL/6J (B6.WT) mice. The underlying pathogenic mechanism of this fatal disease has so far remained elusive. We found that B6.WT mice defici
Publikováno v:
The Journal of Immunology. 196:131.20-131.20
Cutaneous leishmaniasis in resistant C57BL/6 (B6.WT) mice is resolved spontaneously by Th-1 mediated production of TNF-α and IFN-γ, with consequent induction of inducible nitric oxide synthase. Intriguingly, C57BL/6 mice with a TNF gene knockout (B