FOLFOXIRI Plus Panitumumab As First-Line Treatment of

Autor: Dominik P, Modest, Uwe M, Martens, Jorge, Riera-Knorrenschild, Jobst, Greeve, Axel, Florschütz, Swen, Wessendorf, Thomas, Ettrich, Stephan, Kanzler, Dominik, Nörenberg, Jens, Ricke, Max, Seidensticker, Swantje, Held, Petra, Buechner-Steudel, Jens, Atzpodien, Volker, Heinemann, Thomas, Seufferlein, Andrea, Tannapfel, Anke C, Reinacher-Schick, Michael, Geissler

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37(35)

This trial investigated the addition of panitumumab to triplet chemotherapy with fluorouracil/folinic acid, oxaliplatin, and irinotecan (FOLFOXIRI) in a two-to-one randomized, controlled, open-label, phase II trial in patients with untreatedThe prima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6763a0adf53702aee67eb7ce50c868c8
https://pubmed.ncbi.nlm.nih.gov/31609637

Involvement of KSRP in the post-transcriptional regulation of human iNOS expression–complex interplay of KSRP with TTP and HuR

Autor: M. Fechir, Andrea Pautz, Thomas Hubrich, Hartmut Kleinert, Jobst Greeve, Katrin Linker

Publikováno v: Nucleic Acids Research
Linker, Katrin; Pautz, Andrea; Fechir, Marcel; Hubrich, Thomas; Greeve, Jobst; Kleinert, Hartmut (2005). Involvement of KSRP in the post-transcriptional regulation of human iNOS expression–complex interplay of KSRP with TTP and HuR. Nucleic acids research, 33(15), pp. 4813-4827. Oxford University Press 10.1093/nar/gki797

We purified the KH-type splicing regulatory protein (KSRP) as a protein interacting with the 3'-untranslated region (3'-UTR) of the human inducible nitric oxide (iNOS) mRNA. Immunodepletion of KSRP enhanced iNOS 3'-UTR RNA stability in in vitro-degra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7386f4cd37c44e1637b8c52cab69510
http://europepmc.org/articles/PMC1192834

Authors reply to I.B. Rogozin and Y.I. Pavlov: ‘The cytidine deaminase AID exhibits similar functional properties in yeast and mammals’

Autor: Kristina Krause, Kenneth B. Marcu, Jobst Greeve

Publikováno v: Molecular Immunology. 43:1924-1926

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1f261e8343649813caad7d9b45e6215
https://doi.org/10.1016/j.molimm.2005.10.014

Characterization of the apolipoprotein B mRNA editing enzyme: no similarity to the proposed mechanism of RNA editing in kinetoplastid protozoa

Autor: James F. Scott, Naveenan Navaratnam, Jobst Greeve

Publikováno v: Nucleic Acids Research. 19:3569-3576

Intestinal apolipoprotein B mRNA is edited at nucleotide 6666 by a C to U transition resulting in a translational stop codon. The enzymatic properties of the editing activity were characterised in vitro using rat enterocyte cytosolic extract. The edi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c652d438ca1c6e0ea0c5644fe35ea2f3
https://doi.org/10.1093/nar/19.13.3569

Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication

Autor: Daniel Candinas, Daniel Inderbitzin, Simon Wain-Hobson, Jobst Greeve, Isabell Greeve, Jean-Pierre Vartanian, Adrian Keogh, François Achermann, Marianne Bonvin, Deborah Stroka, Peter Sommer

Publikováno v: Hepatology
Hepatology, Wiley-Blackwell, 2006, 43 (6), pp.1364-74. ⟨10.1002/hep.21187⟩
Hepatology, 2006, 43 (6), pp.1364-74. ⟨10.1002/hep.21187⟩

International audience; Hypermutations in hepatitis B virus (HBV) DNA by APOBEC3 cytidine deaminases have been detected in vitro and in vivo, and APOBEC3G (A3G) and APOBEC3F (A3F) have been shown to inhibit the replication of HBV in vitro, but the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7d5c8419aae9525490522a1d6be450
https://hal-riip.archives-ouvertes.fr/pasteur-00683855