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Akademický článek

COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types

Autor: Benjamin J. Schmiedel, Job Rocha, Cristian Gonzalez-Colin, Sourya Bhattacharyya, Ariel Madrigal, Christian H. Ottensmeier, Ferhat Ay, Vivek Chandra, Pandurangan Vijayanand

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Immune cells are important in the pathogenesis of COVID-19. Here the authors assessed the effects of COVID-19-risk variants on gene expression in a range of immune cell types, highlighting their potential to impact the function of diverse immune cell

Externí odkaz: https://doaj.org/article/1849316b872d4746b6e5d01562162e4d

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COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types

Autor: Ferhat Ay, Job Rocha, Christian H. Ottensmeier, Ariel Madrigal, Pandurangan Vijayanand, Vivek Chandra, Sourya Bhattacharyya, Cristian Gonzalez-Colin, Benjamin J Schmiedel

Publikováno v: Nature Communications
NATURE COMMUNICATIONS
bioRxiv
article-version (status) pre
article-version (number) 1
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Common genetic polymorphisms associated with COVID-19 illness can be utilized for discovering molecular pathways and cell types driving disease pathogenesis. Given the importance of immune cells in the pathogenesis of COVID-19 illness, here we assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033e8f3d75bf55dcd8eaa992f2296c17
https://doi.org/10.1101/2020.12.01.407429