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pro vyhledávání: '"Job Herman Berkhout"'
Publikováno v:
Research Journal of Pharmacy and Technology. :2714-2716
Proper knowledge of the pKa value of a compound is of uttermost importance for understanding the behavior of a drug inside the body. The pKa value of Nonselective alpha-1 and beta-blocker Carvedilol shows controversies in literature, whereas values b
Autor:
Aswatha Ram Hn, Job Herman Berkhout
Publikováno v:
Indian Journal of Pharmaceutical Education and Research. 53:s475-s480
The pKa value is a key feature in Absorption, Distribution, Metabolism and Excretion (ADME) of drugs, thus knowing this value is critical in drug development. In this review,pKa values determined in the past decade, using UV-Vis spectrometry, are dis