Výsledky vyhledávání

Akademický článek

The diagnostic accuracy of lung ultrasound to determine PiCCO-derived extravascular lung water in invasively ventilated patients with COVID-19 ARDS

Autor: Leila N. Atmowihardjo, Job R. Schippers, Mark E. Haaksma, Marry R. Smit, Harm J. Bogaard, Leo Heunks, Nicole P. Juffermans, Marcus J. Schultz, Henrik Endeman, Patricia van Velzen, Pieter R. Tuinman, Jurjan Aman, Lieuwe D. J. Bos

Publikováno v: The Ultrasound Journal, Vol 15, Iss 1, Pp 1-11 (2023)

Abstract Background Lung ultrasound (LUS) can detect pulmonary edema and it is under consideration to be added to updated acute respiratory distress syndrome (ARDS) criteria. However, it remains uncertain whether different LUS scores can be used to q

Externí odkaz: https://doaj.org/article/d474e83ef80d45cc9a8302595f1e262f

Zobrazit plný text záznamu

Akademický článek

Efficacy and safety of intravenous imatinib in COVID-19 ARDS: a randomized, double-blind, placebo-controlled clinical trial

Publikováno v: Critical Care, Vol 27, Iss 1, Pp 1-13 (2023)

Abstract Purpose A hallmark of acute respiratory distress syndrome (ARDS) is hypoxaemic respiratory failure due to pulmonary vascular hyperpermeability. The tyrosine kinase inhibitor imatinib reversed pulmonary capillary leak in preclinical studies a

Externí odkaz: https://doaj.org/article/9b66fd0c759d40f6b53c6782c1837294

Zobrazit plný text záznamu

Akademický článek

The INVENT COVID trial: a structured protocol for a randomized controlled trial investigating the efficacy and safety of intravenous imatinib mesylate (Impentri®) in subjects with acute respiratory distress syndrome induced by COVID-19

Autor: Leila Atmowihardjo, Job R. Schippers, Imke H. Bartelink, Pierre M. Bet, Nienke van Rein, Keith Purdy, David Cavalla, Valérie Comberiati, Andrew McElroy, Sue D. Snape, Harm Jan Bogaard, Leo Heunks, Nicole Juffermans, Marcus Schultz, Pieter R. Tuinman, Lieuwe D. J. Bos, Jurjan Aman

Publikováno v: Trials, Vol 23, Iss 1, Pp 1-17 (2022)

Abstract Background The coronavirus disease 2019 (COVID-19) pandemic has led to a disruptive increase in the number of intensive care unit (ICU) admissions with acute respiratory distress syndrome (ARDS). ARDS is a severe, life-threatening medical co

Externí odkaz: https://doaj.org/article/27dbdb47d79d4a0092fff3b3856e4135

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

The effects of training impulse control on simulated driving

Autor: Hatfield, Julie, Williamson, Ann, Kehoe, E. James, Lemon, James, Arguel, Amaël, Prabhakharan, Prasannah, Job, R. F. Soames

Publikováno v: In Accident Analysis and Prevention October 2018 119:1-15

Zobrazit plný text záznamu

Cardiac Safety of Imatinib for the Treatment of COVID-19: A Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial

Autor: Duijvelaar, Erik, Vanhove, Arthur, Schippers, Job R., Smeele, Patrick J., De Man, Frances S., Pinto, Yigal, Aman, Jurjan, Bogaard, Harm Jan

Publikováno v: Journal of cardiovascular pharmacology, 80(6), 783-791. Lippincott Williams and Wilkins
Journal of Cardiovascular Pharmacology, 80(6), 783-791. Lippincott Williams and Wilkins Ltd.
Duijvelaar, E, Vanhove, A, Schippers, J R, Smeele, P J, de Man, F S, Pinto, Y, Aman, J, Bogaard, H J & CounterCOVID Collaborative Group 2022, ' Cardiac Safety of Imatinib for the Treatment of COVID-19 : A Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial ', Journal of Cardiovascular Pharmacology, vol. 80, no. 6, pp. 783-791 . https://doi.org/10.1097/FJC.0000000000001344

Although previous studies support the clinical benefit of imatinib regarding respiratory status in hospitalized patients with COVID-19, potential cardiotoxicity may limit its clinical application. This study aimed to investigate the cardiac safety of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e60be516e0307d63f9a27a156a3bb41
https://doi.org/10.1097/fjc.0000000000001344

Zobrazit plný text záznamu