Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joaquina Farias"'
Autor:
Andres Di Paolo, Joaquin Garat, Guillermo Eastman, Joaquina Farias, Federico Dajas-Bailador, Pablo Smircich, José Roberto Sotelo-Silveira
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Functional genomics studies through transcriptomics, translatomics and proteomics have become increasingly important tools to understand the molecular basis of biological systems in the last decade. In most cases, when these approaches are applied to
Externí odkaz:
https://doaj.org/article/25620b23d6e24d2aba50419f168d1fd7
Autor:
Lucia Vázquez Alberdi, Gonzalo Rosso, Lucía Velóz, Carlos Romeo, Joaquina Farias, María Vittoria Di Tomaso, Miguel Calero, Alejandra Kun
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 515 (2022)
Charcot-Marie-Tooth (CMT) syndrome is the most common progressive human motor and sensory peripheral neuropathy. CMT type 1E is a demyelinating neuropathy affecting Schwann cells due to peripheral-myelin-protein-22 (PMP22) mutations, modelized by Tre
Externí odkaz:
https://doaj.org/article/6c7603d6b3604962a24865e82ca883db
Autor:
Lucía Canclini, Joaquina Farias, Andrés Di Paolo, José R Sotelo-Silveira, Gustavo Folle, Alejandra Kun, José R Sotelo
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233651 (2020)
Transference of RNAs and ribosomes from Schwann cell-to-axon was demonstrated in normal and regenerating peripheral nerves. Previously, we have shown that RNAs transfer is dependent on F-actin cytoskeleton and Myosin Va. Here, we explored the contrib
Externí odkaz:
https://doaj.org/article/9966cec96f4b47d9b5b29b4071ad53ca
Autor:
Raquel Mesquita-Ribeiro, Rafael Sebastián Fort, Alex Rathbone, Joaquina Farias, Cristiano Lucci, Victoria James, Jose Sotelo-Silveira, Maria Ana Duhagon, Federico Dajas-Bailador
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
COLIBRI
Universidad de la República
instacron:Universidad de la República
article-version (VoR) Version of Record
COLIBRI
Universidad de la República
instacron:Universidad de la República
Neurons have highlighted the needs for decentralized gene expression and specific RNA function in somato-dendritic and axonal compartments, as well as in intercellular communication via extracellular vesicles (EVs). Despite advances in miRNA biology,
Autor:
Andrés Di Paolo, José Roberto Sotelo Silveira, Thomas Kislinger, Joaquin Garat, Andrew Macklin, Joaquina Farias, Vladimir Ignatchenko
Publikováno v:
Journal of Proteome Research. 20:2506-2520
Axons are complex subcellular compartments that are extremely long in relation to cell bodies, especially in peripheral nerves. Many processes are required and regulated during axon injury, including anterograde and retrograde transport, glia-to-axon
Positive Selection in the Chloroplastic ATP-Synthase β-Subunit and Its Relation to Virulence Factors
Autor:
Facundo Giorello, Joaquina Farias
Publikováno v:
Journal of Molecular Evolution. 88:703-713
The most paradigmatic examples of molecular evolution under positive selection involve genes related to the immune system. Recently, different chloroplastic factors have been shown to be important for plant defenses, among them, the α- and β-subuni
Publikováno v:
COLIBRI
Universidad de la República
instacron:Universidad de la República
RNA
Universidad de la República
instacron:Universidad de la República
RNA
Axonal protein synthesis has been shown to play a role in developmental and regenerative growth, as well as in the maintenance of the axoplasm in a steady state. Recent studies have begun to identify the mRNAs localized in axons, which could be trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b4dfd1ca727a76b95f53ffc6017f80
Autor:
Thomas Kislinger, Andrés Di Paolo, Federico Dajas-Bailador, Nancy H. Colburn, Guillermo Eastman, Raquel Mesquita-Ribeiro, José R. Sotelo-Silveira, David J. Munroe, Joaquina Farias, José Roberto Sotelo Sosa, Andrew Macklin
Publikováno v:
COLIBRI
Universidad de la República
instacron:Universidad de la República
RNA
Universidad de la República
instacron:Universidad de la República
RNA
Programmed cell death 4 (PDCD4) protein is a tumor suppressor that inhibits translation through the mTOR-dependent initiation factor EIF4A, but its functional role and mRNA targets in neurons remain largely unknown. Our work identified that PDCD4 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c4e3dd62eb1dded09339cbdf6e29a8
Publikováno v:
Acta tropica. 199
Echinococcus granulosus is a cestode parasite whose cytoskeleton plasticity allows it to enter and develop inside its hosts, completing thus its life cycle. We focused our attention on F-actin organization and distribution in E. granulosus protoscole
Autor:
Lucía Canclini, Aldo Calliari, Joaquina Farias, José R. Sotelo, Agostina Puppo, David J. Munroe, José R. Sotelo-Silveira, John A. Mercer
Publikováno v:
Developmental Neurobiology. 74:382-396
Sorting of specific mRNAs to particular cellular locations and regulation of their translation is an essential mechanism underlying cell polarization. The transport of RNAs by kinesins and dyneins has been clearly established in several cell models,