Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joaquin L. J. Quintana"'
Autor:
Jamie L. Dombach, Grace L. Christensen, Samual C. Allgood, Joaquin L. J. Quintana, Corrella S. Detweiler
Publikováno v:
mSphere, Vol 9, Iss 3 (2024)
ABSTRACTNew molecular approaches to disrupting bacterial infections are needed. The bacterial cell membrane is an essential structure with diverse potential lipid and protein targets for antimicrobials. While rapid lysis of the bacterial cell membran
Externí odkaz:
https://doaj.org/article/deacbcd304cd4da1aa001dd888ba6abe
Autor:
Joseph A. Villanueva, Amy L. Crooks, Toni A. Nagy, Joaquin L. J. Quintana, Zachary D. Dalebroux, Corrella S. Detweiler
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Gram-negative bacteria have a robust cell envelope that excludes or expels many antimicrobial agents. However, during infection, host soluble innate immune factors permeabilize the bacterial outer membrane. We identified two small molecules
Externí odkaz:
https://doaj.org/article/10a9deb02844414790adf04531996640
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Untreatable bacterial infections are a critical public health care issue. In addition to increasing antibiotic resistance, bacteria that are in slow-growing or nongrowing states, or that live inside mammalian cells, are typically insensitive to clini
Externí odkaz:
https://doaj.org/article/a68af8cbc9f5475c85a35b8a114d37ca
Publikováno v:
ACS Infectious Diseases. 6:1238-1249
Drug resistant pathogens are on the rise and new treatments are needed for bacterial infections. Efforts toward antimicrobial discovery typically identify compounds that prevent bacterial growth in...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6384c7d0b67a0f0592e76393f4743808
https://doi.org/10.1021/acsinfecdis.0c00023
https://doi.org/10.1021/acsinfecdis.0c00023
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
mBio
mBio
Rates of antibiotic and multidrug resistance are rapidly rising, leaving fewer options for successful treatment of bacterial infections. In addition to acquiring genetic resistance, many pathogens form persister cells, form biofilms, and/or cause int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1de1d513054118bc1a649bd11537bc9
https://journals.asm.org/doi/10.1128/mBio.01801-21
https://journals.asm.org/doi/10.1128/mBio.01801-21
Autor:
Chun Wan, Corrella S. Detweiler, Edward W. Yu, Haijia Yu, Toni A. Nagy, Jamie L. Dombach, Chih-Chia Su, Amy L. Crooks, Jingshi Shen, Joaquin L. J. Quintana
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 12, p e1009119 (2020)
PLoS Pathogens, Vol 16, Iss 12, p e1009119 (2020)
Infections caused by Gram-negative bacteria are difficult to fight because these pathogens exclude or expel many clinical antibiotics and host defense molecules. However, mammals have evolved a substantial immune arsenal that weakens pathogen defense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cd9ee444c1f3892de872c62a32df73
https://pubmed.ncbi.nlm.nih.gov/33290418
https://pubmed.ncbi.nlm.nih.gov/33290418
Publikováno v:
ACS Infect Dis
Drug resistant pathogens are on the rise, and new treatments are needed for bacterial infections. Efforts toward antimicrobial discovery typically identify compounds that prevent bacterial growth in microbiological media. However, the micro-environme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb8596a91cd8a3073c11ff9272bab65c
https://pubmed.ncbi.nlm.nih.gov/32272013
https://pubmed.ncbi.nlm.nih.gov/32272013
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Salmonella enterica are natural bacterial pathogens of humans and animals that cause systemic infection or gastroenteritis. During systemic infection, Salmonella generally reside within professional phagocytes, typically macrophages, whereas gastroen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2fa6552177257b64739db827cc99828
https://doi.org/10.1128/aac.01536-19
https://doi.org/10.1128/aac.01536-19
Publikováno v:
Antimicrobial Agents and Chemotherapy
Salmonella enterica is a natural bacterial pathogen of humans and animals that causes systemic infection or gastroenteritis. During systemic infection, Salmonella generally resides within professional phagocytes, typically macrophages, whereas gastro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92381e88aa896646a660c95aa6e226dc
https://pubmed.ncbi.nlm.nih.gov/31591121
https://pubmed.ncbi.nlm.nih.gov/31591121
Autor:
Jamie L Dombach, Joaquin L J Quintana, Toni A Nagy, Chun Wan, Amy L Crooks, Haijia Yu, Chih-Chia Su, Edward W Yu, Jingshi Shen, Corrella S Detweiler
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009119 (2020)
Infections caused by Gram-negative bacteria are difficult to fight because these pathogens exclude or expel many clinical antibiotics and host defense molecules. However, mammals have evolved a substantial immune arsenal that weakens pathogen defense
Externí odkaz:
https://doaj.org/article/e71fb853cf1342718633c6731e647203