Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Joaquín Fernández- Irigoyen"'
Autor:
Paula Aparicio, David Navarrete‐Villanueva, Alba Gómez‐Cabello, Tresa López‐Royo, Enrique Santamaría, Joaquín Fernández‐Irigoyen, Karina Ausín, Manuel Arruebo, Victor Sebastian, Germán Vicente‐Rodríguez, Rosario Osta, Raquel Manzano
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 1883-1897 (2024)
Abstract Background Sarcopenia, the gradual and generalized loss of muscle mass and function with ageing, is one of the major health problems in older adults, given its high prevalence and substantial socioeconomic implications. Despite the extensive
Externí odkaz:
https://doaj.org/article/d1f9518606374239b3f7f8bf3ae2919c
Autor:
Júlia Solana-Balaguer, Pol Garcia-Segura, Genís Campoy-Campos, Almudena Chicote-González, Joaquín Fernández-Irigoyen, Enrique Santamaría, Esther Pérez-Navarro, Mercè Masana, Jordi Alberch, Cristina Malagelada
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Huntington’s disease (HD) is a neurological disorder caused by a CAG expansion in the Huntingtin gene (HTT). HD pathology mostly affects striatal medium-sized spiny neurons and results in an altered cortico-striatal function. Recent studie
Externí odkaz:
https://doaj.org/article/06a7d592cf8441f28e2a2b4412620870
Autor:
Lara Matilla, Ernesto Martín-Núñez, Mattie Garaikoetxea, Adela Navarro, Ibai Tamayo, Amaya Fernández-Celis, Alicia Gainza, Joaquín Fernández-Irigoyen, Enrique Santamaría, Pieter Muntendam, Virginia Álvarez, Rafael Sádaba, Eva Jover, Natalia López-Andrés
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Aortic stenosis (AS) is characterized by inflammation, fibrosis, osteogenesis and angiogenesis. Men and women develop these mechanisms differently. Galectin-3 (Gal-3) is a pro-inflammatory and pro-osteogenic lectin in AS. In this
Externí odkaz:
https://doaj.org/article/217c4fe6128f48c391c01c6594c7805f
Autor:
Bernardo Abel Cedeno-Veloz, Lucía Lozano-Vicario, Fabricio Zambom-Ferraresi, Joaquín Fernández-Irigoyen, Enrique Santamaría, Alba Rodríguez-García, Roman Romero-Ortuno, Jaime Mondragon-Rubio, Javier Ruiz-Ruiz, Robinson Ramírez-Vélez, Mikel Izquierdo, Nicolás Martínez-Velilla
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Osteoporosis is a skeletal disease that can increase the risk of fractures, leading to adverse health and socioeconomic consequences. However, current clinical methods have limitations in accurately estimating fracture risk, particularly in
Externí odkaz:
https://doaj.org/article/8a592bb4227b44f69c336be12c51e468
Autor:
Carmen Badosa, Mónica Roldán, Joaquín Fernández-Irigoyen, Enrique Santamaria, Cecilia Jimenez-Mallebrera
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Extracellular vesicles (EVs) are key mediators of cell-to-cell communication. Their content reflects the state of diseased cells representing a window into disease progression. Collagen-VI Related Muscular Dystrophy (COL6-RD) is a multi-syst
Externí odkaz:
https://doaj.org/article/0e036d0acc6946a0b903a885b6705791
Autor:
Júlia Solana‐Balaguer, Núria Martín‐Flores, Pol Garcia‐Segura, Genís Campoy‐Campos, Leticia Pérez‐Sisqués, Almudena Chicote‐González, Joaquín Fernández‐Irigoyen, Enrique Santamaría, Esther Pérez‐Navarro, Jordi Alberch, Cristina Malagelada
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) play a crucial role in intercellular communication, participating in the paracrine trophic support or in the propagation of toxic molecules, including proteins. RTP801 is a stress‐regulated protein, whose level
Externí odkaz:
https://doaj.org/article/dfb176b0086a47cd9b888eb3c0d1f769
Autor:
Paz Cartas-Cejudo, Mercedes Lachén-Montes, Isidro Ferrer, Joaquín Fernández-Irigoyen, Enrique Santamaría
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-20 (2023)
Highlights Quantitative proteomics is a useful approach to biochemically characterize the pathological neurodegeneration that occurs at the level of olfactory areas. Alteration in the olfactory tract proteostasis is more severe in AD than in PD. Prot
Externí odkaz:
https://doaj.org/article/51a1490cd1804b4fa047cd854eafeefd
Autor:
Mercedes Lachén-Montes, Paz Cartas-Cejudo, Adriana Cortés, Elena Anaya-Cubero, Erika Peral, Karina Ausín, Ramón Díaz-Peña, Joaquín Fernández-Irigoyen, Enrique Santamaría
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 394 (2024)
Alzheimer’s disease (AD) is a neurodegenerative olfactory disorder affecting millions of people worldwide. Alterations in the hexosamine- or glucose-related pathways have been described through AD progression. Specifically, an alteration in glucosa
Externí odkaz:
https://doaj.org/article/6e5775ae53e0466c91ac6350056218d1
Autor:
Paz Cartas-Cejudo, Adriana Cortés, Mercedes Lachén-Montes, Elena Anaya-Cubero, Joaquín Fernández-Irigoyen, Enrique Santamaría
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 7, Pp 1997-1998 (2025)
Externí odkaz:
https://doaj.org/article/b790212e1aa449d7b064f99b18ae011b
Autor:
Rodrigo Vinueza-Gavilanes, Jorge Juan Bravo-González, Leyre Basurco, Chiara Boncristiani, Joaquín Fernández-Irigoyen, Enrique Santamaría, Irene Marcilla, Alberto Pérez-Mediavilla, María Rosario Luquin, Africa Vales, Gloria González-Aseguinolaza, María Soledad Aymerich, Tomás Aragón, Montserrat Arrasate
Publikováno v:
Neurobiology of Disease, Vol 183, Iss , Pp 106166- (2023)
Synucleinopathies are a group of neurodegenerative diseases without effective treatment characterized by the abnormal aggregation of alpha-synuclein (aSyn) protein. Changes in levels or in the amino acid sequence of aSyn (by duplication/triplication
Externí odkaz:
https://doaj.org/article/25360ce393ad40769705ef541732c8f6