Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joaquín Bonelli"'
Autor:
Yuxiang Zhou, David Hou, Cristina Cusco Marigo, Joaquín Bonelli, Pau Rocas, Fangzhou Cheng, Xiaoqiu Yang, Josep Rocas, Naomi M. Hamberg, Jingyan Han
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105390- (2022)
Summary: Aortic endothelial cell dysfunction is an early trigger of atherosclerosis, the major cause of the cardiovascular disease (CVD). Nanomedicines targeting vascular endothelium and lesions hold great promise as therapeutic solutions to vascular
Externí odkaz:
https://doaj.org/article/84053fbe8b5744c788b6577023491ad1
Autor:
Joaquín Bonelli, María Velasco-de Andrés, Neus Isidro, Cristina Bayó, Sergi Chumillas, Laura Carrillo-Serradell, Sergi Casadó-Llombart, Cheryl Mok, Daniel Benítez-Ribas, Francisco Lozano, Josep Rocas, Vicente Marchán
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 58 (2022)
Encapsulation of water-soluble bioactive compounds for enabling specific accumulation in tumor locations, while avoiding premature clearance and/or degradation in the bloodstream, is one of the main hallmarks in nanomedicine, especially that of NIR f
Externí odkaz:
https://doaj.org/article/40adc6dc96854439a914bcdbba777c1f
Autor:
Joaquín Bonelli, Enrique Ortega-Forte, Anna Rovira, Manel Bosch, Oriol Torres, Cristina Cuscó, Josep Rocas, José Ruiz, Vicente Marchán
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Integration of photosensitizers (PSs) within nanoscale delivery systems offers great potential for overcoming some of the 'Achiles' heels' of photodynamic therapy (PDT). Herein, we have encapsulated a mitochondria-targeted coumarin PS into amphoteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d105d0d5676cdd16b07b2be4fab2dea
https://doi.org/10.1021/acs.biomac.2c00361
https://doi.org/10.1021/acs.biomac.2c00361
Autor:
Joaquín Bonelli, Enrique Ortega-Forte, Gloria Vigueras, Manel Bosch, Natalia Cutillas, Josep Rocas, José Ruiz, Vicente Marchán
Publikováno v:
Inorganic Chemistry Frontiers. 9:2123-2138
Cyclometalated Ir(III) complexes hold great promise as an alternative to platinum metallodrugs for the therapy and diagnosis of cancer. However, their low aqueous solubility and poor cell membrane permeability are obstacles for in vivo applications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46685c8cb0dec0a2672802fea64173cf
https://doi.org/10.1039/d1qi01542g
https://doi.org/10.1039/d1qi01542g
Autor:
Vicente Marchán, Joaquín Bonelli, Enrique Ortega-Forte, José Ruiz, Anna Rovira, Manel Bosch, Albert Gandioso
Publikováno v:
Journal of Medicinal Chemistry
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Photodynamic therapy (PDT) for cancer treatment has drawn increased attention over the last decades. Herein, we introduce a novel family of low-molecular-weight coumarins as potential PDT anticancer tools. Through a systematic study with a library of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8d6b052db1b4b49303cab45626cf21
http://hdl.handle.net/2445/183273
http://hdl.handle.net/2445/183273
Publikováno v:
Chemistry, Vol 5, Iss 2, Pp 703-712 (2023)
For some time, the presence of high oxidation state Mn ions and Ca(II) in the active center of Photosystem II has been known. However, coordination complexes that combine both Mn(III) and Ca(II) have been difficult to obtain, with only a handful of e
Externí odkaz:
https://doaj.org/article/bf35b0c755084ee2ac817fb69bd619a0
Autor:
Marta Pérez-Hernández, Cristina Cuscó, Cristina Benítez-García, Joaquin Bonelli, Marina Nuevo-Fonoll, Aroa Soriano, David Martínez-García, Alain Arias-Betancur, María García-Valverde, Miguel F. Segura, Roberto Quesada, Josep Rocas, Vanessa Soto-Cerrato, Ricardo Pérez-Tomás
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 508 (2021)
Cancer is one of the leading causes of mortality worldwide due, in part, to limited success of some current therapeutic approaches. The clinical potential of many promising drugs is restricted by their systemic toxicity and lack of selectivity toward
Externí odkaz:
https://doaj.org/article/d89645dafa60469fa260e1a3ca6e34a9