Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joaquín, Botta"'
Autor:
David Moreno-Delgado, Mar Puigdellívol, Estefanía Moreno, Mar Rodríguez-Ruiz, Joaquín Botta, Paola Gasperini, Anna Chiarlone, Lesley A Howell, Marco Scarselli, Vicent Casadó, Antoni Cortés, Sergi Ferré, Manuel Guzmán, Carmen Lluís, Jordi Alberch, Enric I Canela, Silvia Ginés, Peter J McCormick
Publikováno v:
eLife, Vol 9 (2020)
Early Huntington’s disease (HD) include over-activation of dopamine D1 receptors (D1R), producing an imbalance in dopaminergic neurotransmission and cell death. To reduce D1R over-activation, we present a strategy based on targeting complexes of D1
Externí odkaz:
https://doaj.org/article/e29f5e9398d54a2882b616c452b949ae
Autor:
Carlos, Costas-Insua, Estefanía, Moreno, Irene B, Maroto, Andrea, Ruiz-Calvo, Raquel, Bajo-Grañeras, David, Martín-Gutiérrez, Rebeca, Diez-Alarcia, M Teresa, Vilaró, Roser, Cortés, Nuria, García-Font, Ricardo, Martín, Marc, Espina, Joaquín, Botta, Silvia, Ginés, Peter J, McCormick, José, Sánchez-Prieto, Ismael, Galve-Roperh, Guadalupe, Mengod, Leyre, Urigüen, Giovanni, Marsicano, Luigi, Bellocchio, Enric I, Canela, Vicent, Casadó, Ignacio, Rodríguez-Crespo, Manuel, Guzmán
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 41(38)
Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1 cannabinoid receptor (CB
Autor:
David, Moreno-Delgado, Mar, Puigdellívol, Estefanía, Moreno, Mar, Rodríguez-Ruiz, Joaquín, Botta, Paola, Gasperini, Anna, Chiarlone, Lesley A, Howell, Marco, Scarselli, Vicent, Casadó, Antoni, Cortés, Sergi, Ferré, Manuel, Guzmán, Carmen, Lluís, Jordi, Alberch, Enric I, Canela, Silvia, Ginés, Peter J, McCormick
Publikováno v:
eLife
Early Huntington’s disease (HD) include over-activation of dopamine D1 receptors (D1R), producing an imbalance in dopaminergic neurotransmission and cell death. To reduce D1R over-activation, we present a strategy based on targeting complexes of D1
Autor:
Juan A, González-Vera, Rocío A, Medina, Mar, Martín-Fontecha, Angel, Gonzalez, Tania, de la Fuente, Henar, Vázquez-Villa, Javier, García-Cárceles, Joaquín, Botta, Peter J, McCormick, Bellinda, Benhamú, Leonardo, Pardo, María L, López-Rodríguez
Publikováno v:
Scientific Reports
Serotonin 5-HT6 receptor has been proposed as a promising therapeutic target for cognition enhancement though the development of new antagonists is still needed to validate these molecules as a drug class for the treatment of Alzheimer’s disease an
Autor:
Estefanía, Moreno, Anna, Chiarlone, Mireia, Medrano, Mar, Puigdellívol, Lucka, Bibic, Lesley A, Howell, Eva, Resel, Nagore, Puente, María J, Casarejos, Juan, Perucho, Joaquín, Botta, Nuria, Suelves, Francisco, Ciruela, Silvia, Ginés, Ismael, Galve-Roperh, Vicent, Casadó, Pedro, Grandes, Beat, Lutz, Krisztina, Monory, Enric I, Canela, Carmen, Lluís, Peter J, McCormick, Manuel, Guzmán
Publikováno v:
Neuropsychopharmacology
The dorsal striatum is a key node for many neurobiological processes such as motor activity, cognitive functions, and affective processes. The proper functioning of striatal neurons relies critically on metabotropic receptors. Specifically, the main