Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joao Villares"'
Autor:
Minh Bao Huynh, Joao Villares, Nadia Soussi-Yanicostas, Rita Raisman-Vozari, Ayikoe Guy Mensah-Nyagan, Julia E. Sepulveda-Diaz, Sandrine Chantepie, Seyedeh Maryam Alavi Naini, Toin H. van Kuppevelt, Dulce Papy-Garcia, Constantin Yanicostas, Estelle Jospin, Foudil Lamari, Mohand Ouidir Ouidja
Publikováno v:
Brain, 138, 1339-54
Brain, 138, Pt 5, pp. 1339-54
Brain, 138, Pt 5, pp. 1339-54
Item does not contain fulltext Heparan sulphate (glucosamine) 3-O-sulphotransferase 2 (HS3ST2, also known as 3OST2) is an enzyme predominantly expressed in neurons wherein it generates rare 3-O-sulphated domains of unknown functions in heparan sulpha
Autor:
Gustavo Tureck, Elizabeth Suchi Chen, Josianne Thomazini Fukasawa, Lucieni Conterno de Oliveira, Lucas Trevizani Rasmussen, Spencer Luiz Marques Payão, Roger Willian de Labio, Joao Villares, Marília de Arruda Cardoso Smith
Publikováno v:
Current Alzheimer research. 15(2)
Background: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular amyloid plaque and neurofibrillary tangles in the brain. Studies have shown that neurons are able to re-enter the cell cycle, but not enough to enable
Autor:
Isabela Bazzo da Costa, Lucas Trevizani Rasmussen, Elizabeth Suchi Chen, Gustavo Arruda Viani, Roger Willian de Labio, Gustavo Turecki, Marília de Arruda Cardoso Smith, Spencer Luiz Marques Payão, Joao Villares
Publikováno v:
Current Alzheimer research. 14(7)
Background: Alzheimer's disease (AD) is defined as a progressive and irreversible neurodegenerative disorder, the onset of which is mainly characterized by decreased cognition, memory loss, and mental confusion. Objective: This study sought to quanti
Autor:
Marília de Arruda Cardoso Smith, Roger Willian de Labio, Thais Minett, Spencer Luiz Marques Payão, Sandra A. Drigo, Gustavo Arruda Viani, Lucas Trevizani Rasmussen, Joao Villares, Paulo-Henrique Bertolucci, Gustavo Turecki, Danielle Cecyre, Elizabeth S. Chen
Publikováno v:
Current Alzheimer research. 12(10)
Changes in rRNA and rDNA expression have been associated with cellular and organism aging and have been linked to Alzheimer's disease (AD) pathogenesis. In this study, we investigated the mRNA expression of ribosomal genes (28S/18S) and β-amyloid pr
Autor:
Marília de Arruda Cardoso Smith, Sandra Aparecido Linde, Spencer-Luiz Payão, Isabela-Bazzo Costa, Elizabeth Suchi Chen, Roger Delabio, Lucas Trevizani Rasmussen, Gustavo Turecki, Gustavo-Arruda Viani, Igor Mizumoto, Joao Villares
Publikováno v:
Journal of Alzheimer's disease : JAD. 42(3)
Presenilin 1 (PSEN1) and presenilin 2 (PSEN2) genes encode the major component of y-secretase, which is responsible for sequential proteolytic cleavages of amyloid precursor proteins and the subsequent formation of amyloid-β peptides. 150 RNA sample
Autor:
Joao Villares, João Norberto Stávale
Publikováno v:
Experimental Neurology. 171:391-404
The present study examined the regional differences in dopamine transporter binding sites and NMDA receptor complex binding based on autoradiographic images obtained in postmortem sections of human normal brain tissues. In middle-aged control tissues
Autor:
Luiz E. Mello, Joao Villares
Publikováno v:
Psychiatric Clinics of North America. 20:691-704
This article deals with the neuroanatomic aspects of the basal ganglia with regard to different neurotransmitter systems and to different diseases. A general scheme of these circuits with the overall distinction between limbic-associative and motor c
Autor:
Stéphane Lehéricy, Jean-Philippe Brandel, Etienne C. Hirsch, Philippe Anglade, Joao Villares, Daniel Scherman, Charles Duyckaerts, France Javoy-Agid, Yves Agid
Publikováno v:
Brain Research. 659:1-9
The monoaminergic innervation of the caudate nucleus, putamen and ventral striatum was investigated post mortem, in patients with Parkinson's and Alzheimer's disease as compared to control subjects, by autoradiographic detection of tritiated dihydrot
Publikováno v:
Jornal Brasileiro de Psiquiatria, Volume: 60, Issue: 2, Pages: 111-122, Published: 2011
Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Jornal Brasileiro de Psiquiatria, Vol 60, Iss 2, Pp 111-122 (2011)
Jornal Brasileiro de Psiquiatria v.60 n.2 2011
Jornal Brasileiro de Psiquiatria
Universidade Federal do Rio de Janeiro (UFRJ)
instacron:UFRJ
Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Jornal Brasileiro de Psiquiatria, Vol 60, Iss 2, Pp 111-122 (2011)
Jornal Brasileiro de Psiquiatria v.60 n.2 2011
Jornal Brasileiro de Psiquiatria
Universidade Federal do Rio de Janeiro (UFRJ)
instacron:UFRJ
OBJETIVOS: Diante das lacunas na efetividade das terapêuticas para transtornos por uso de Cannabis, a droga ilícita mais consumida no mundo, este trabalho propõe-se a rever os conhecimentos sobre o substrato neuroanatômico, biomolecular e celular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01d2a9b0ce9298abc2871c8dfc3f183
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852011000200006&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852011000200006&lng=en&tlng=en
Autor:
Minh Bao Huynh, Ludmilla Sissoeff, Dulce Papy-Garcia, Stephy Christiaans, Julia Elisa Sepúlveda Díaz, Rita Raisman-Vozari, Gilles Carpentier, Mohand Ouidir Ouidja, Joao Villares
Publikováno v:
Neurobiology of Aging. 33:1005.e11-1005.e22
Glycosaminoglycans (GAGs) are major extracellular matrix components known to tightly regulate cell behavior by interacting with tissue effectors as trophic factors and other heparin binding proteins. Alterations of GAGs structures might thus modify t