Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joao Vasco Ferreira"'
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Aging is a risk factor for a number of diseases, being the more notorious ones perhaps neurodegenerative diseases such as Alzheimer’s and Parkinson’s. These and other age-related pathologies are often associated with accumulation of proteotoxic m
Externí odkaz:
https://doaj.org/article/41ff246a60bb46a5a82caf1fd657f6a6
Autor:
Joao Vasco Ferreira, Ana Rosa Soares, José S Ramalho, Teresa Ribeiro-Rodrigues, Catarina Máximo, Mónica Zuzarte, Henrique Girão, Paulo Pereira
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223790 (2019)
Deregulation of proteostasis is a main feature of many age-related diseases, often leading to the accumulation of toxic oligomers and insoluble protein aggregates that accumulate intracellularly or in the extracellular space. To understand the mechan
Externí odkaz:
https://doaj.org/article/6539ff22c30347249ea4887221d9ffcd
Autor:
José C. Ramalho, Ana Sofia Carvalho, Henrique Girão, Petra Pintado, Paulo Pereira, Ana Soares, Joao Vasco Ferreira, Guillaume van Niel, Rune Matthiesen, Hans Christian Beck, Catarina Máximo Carvalho, Mónica Zuzarte, Maria Helena Cardoso
Publikováno v:
Science Advances
Science Advances, American Association for the Advancement of Science (AAAS), 2022, 8 (12), pp.eabm1140. ⟨10.1126/sciadv.abm1140⟩
Ferreira, J V, Da Rosa Soares, A, Ramalho, J, Carvalho, C M, Cardoso, M H, Pintado, P, Carvalho, A S, Beck, H C, Matthiesen, R, Zuzarte, M, Girao, H, Van Niel, G & Pereira, P 2022, ' LAMP2A regulates the loading of proteins into exosomes ', Science Advances, vol. 8, no. 12, eabm1140 . https://doi.org/10.1126/sciadv.abm1140
Autophagy
Science Advances, American Association for the Advancement of Science (AAAS), 2022, 8 (12), pp.eabm1140. ⟨10.1126/sciadv.abm1140⟩
Ferreira, J V, Da Rosa Soares, A, Ramalho, J, Carvalho, C M, Cardoso, M H, Pintado, P, Carvalho, A S, Beck, H C, Matthiesen, R, Zuzarte, M, Girao, H, Van Niel, G & Pereira, P 2022, ' LAMP2A regulates the loading of proteins into exosomes ', Science Advances, vol. 8, no. 12, eabm1140 . https://doi.org/10.1126/sciadv.abm1140
Autophagy
Exosomes are extracellular vesicles of endosomal origin released by virtually all cell types across metazoans. Exosomes are active vehicles of intercellular communication and can transfer lipids, RNAs and proteins between different cells, tissues or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634ed8e72ebc4611dd8e49a7f5405886
https://hdl.handle.net/10362/135926
https://hdl.handle.net/10362/135926
Autor:
Karen A. Lodermeier, Thomas H. Brannagan, Joao Vasco Ferreira, Steven G. Hughes, Violaine Planté-Bordeneuve, Rickey E. Carter, Jessica Robinson-Papp, Rito Bergemann, Peter J. Dyck, Christina Alves, Julie Khoury, John C. Kincaid, John L. Berk, Matilde Laura, Samar S. Ayache, Carol J. Whelan, Brian M. Drachman, Isabel Conceição, Merrill D. Benson, Sami Khella, Michael Polydefkis, Teresa Coelho, Morie A. Gertz, William J. Litchy, Hayet Salhi, Vinay Chaudhry, Stephen B. Heitner, David H. Adams, Giampaolo Merlini, Andrea Cortese, Janice F. Wiesman, P. James B. Dyck, Namita Goyal, Márcio Cardoso, Christopher J. Klein, Katherine Ruzhansky, Annabel K. Wang, Michelle L. Mauermann, Marcus V. Pinto, Márcia Waddington-Cruz, Jenny L. Davies, Céline Labeyrie, Peter D. Gorevic, Elizabeth J. Ackermann
Publikováno v:
Muscle & Nerve. 56:901-911
Introduction Polyneuropathy signs (Neuropathy Impairment Score, NIS), neurophysiologic tests (m+7Ionis ), disability, and health scores were assessed in baseline evaluations of 100 patients entered into an oligonucleotide familial amyloidotic polyneu
Autor:
Joao Vasco Ferreira
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 36, Iss 5, Pp 375-376 (2017)
Autor:
Bruno Manadas, Joao Vasco Ferreira, Maria João Pinho, Paulo Pereira, Teresa Ribeiro-Rodrigues, Mónica Zuzarte, Tania Martins-Marques, Ana Soares, Steve Catarino, Henrique Girão, Sandra I. Anjo, Joost P.G. Sluijter
Publikováno v:
Scientific Reports
Intercellular communication is vital to ensure tissue and organism homeostasis and can occur directly, between neighbour cells via gap junctions (GJ), or indirectly, at longer distances, through extracellular vesicles, including exosomes. Exosomes, a
Autor:
Sandra I. Anjo, Steve Catarino, Teresa Ribeiro-Rodrigues, Bruno Manadas, Maria João Pinho, Tania Martins-Marques, Joao Vasco Ferreira, Mónica Zuzarte, Henrique Girão, Joost P.G. Sluijter, Paulo Pereira, Ana Soares
Publikováno v:
Scientific Reports
Scientific Reports, 5. Nature Publishing Group
Scientific Reports, 5. Nature Publishing Group
Intercellular communication is vital to ensure tissue and organism homeostasis and can occur directly, between neighbour cells via gap junctions (GJ), or indirectly, at longer distances, through extracellular vesicles, including exosomes. Exosomes, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5906d193acd5d4ae1a97d983d37a0c
https://dspace.library.uu.nl/handle/1874/332141
https://dspace.library.uu.nl/handle/1874/332141
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scientific Reports
We thank Dr. Ana Maria Cuervo for providing the shRNA against Lamp2a and Dr. Cam Patterson for the wild-type and mutant STUB1 constructs. This work was supported by grants from the Portuguese Foundation for Science and Technology (FCT), PTDC/SAU-ORG/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3514989b35e8b7f7520ec2938267bd5
http://www.scopus.com/inward/record.url?scp=84929224667&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=84929224667&partnerID=8YFLogxK
Publikováno v:
Current Topics in Neurotoxicity ISBN: 9783319139388
Depending on the mechanism and molecular players involved in the targeting of a substrate to the lysosome, autophagy can be divided in three different subtypes: Macroautophagy, Microautophagy and Chaperone-Mediated Autophagy (CMA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab82398f5308c8894db4a7183184e136
https://doi.org/10.1007/978-3-319-13939-5_2
https://doi.org/10.1007/978-3-319-13939-5_2
Autor:
Teresa Ribeiro-Rodrigues, Carla Marques, Paulo Pereira, Henrique Girão, Joao Vasco Ferreira, Tânia Martins-Marques, Steve Catarino
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(11)
Gap junctions (GJs) are specialized cell-cell contacts formed by connexins (Cxs), which provide direct intercellular communication between eukaryotic cells. Although Cx43 has long been known to be a substrate for ubiquitination, the reversal of this