Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Joao Pedro de Magalhaes"'
Autor:
Gustavo Daniel Vega Magdaleno, Vladislav Bespalov, Yalin Zheng, Alex A. Freitas, Joao Pedro de Magalhaes
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-28 (2022)
Abstract Background Dietary restriction (DR) is the most studied pro-longevity intervention; however, a complete understanding of its underlying mechanisms remains elusive, and new research directions may emerge from the identification of novel DR-re
Externí odkaz:
https://doaj.org/article/47956275ec04433c9562028b0553f1d0
Autor:
Marcelo Rodrigues de Holanda Maia, Alexandre Plastino, Alex A. Freitas, Joao Pedro de Magalhaes
Publikováno v:
IEEE/ACM transactions on computational biology and bioinformatics.
Data uncertainty remains a challenging issue in many applications, but few classification algorithms can effectively cope with it. An ensemble approach for uncertain categorical features has recently been proposed, achieving promising results. It con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fbe562726eec556324e6e1b495f7f6
https://pubmed.ncbi.nlm.nih.gov/36318566
https://pubmed.ncbi.nlm.nih.gov/36318566
Autor:
Joao Pedro De Magalhaes, Cyril Lagger
Publikováno v:
Nature Aging. 2:468-470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9341c442ebbce5fbb9da8a06cb88dec2
https://doi.org/10.1038/s43587-022-00238-4
https://doi.org/10.1038/s43587-022-00238-4
Autor:
Alexey Moskalev, Zulfiya Guvatova, Ines De Almeida Lopes, Charles W. Beckett, Brian K. Kennedy, Joao Pedro De Magalhaes, Alexander A. Makarov
Publikováno v:
Trends in endocrinology and metabolism: TEM. 33(4)
Geroprotectors slow down aging and promote healthy longevity in model animals. Although hundreds of compounds have been shown to extend the life of laboratory model organisms, clinical studies on potential geroprotectors are exceedingly rare, especia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3121be1e1a228c70fa31e7c8bd29ccb6
https://pubmed.ncbi.nlm.nih.gov/35183431
https://pubmed.ncbi.nlm.nih.gov/35183431
Autor:
Iqra Fatima, Guodong Chen, Natalia V. Botchkareva, Andrey A. Sharov, Daniel Thornton, Holly N. Wilkinson, Matthew J. Hardman, Andreas Grutzkau, Joao Pedro de Magalhaes, Andrei Seluanov, Ewan St.J. Smith, Vera Gorbunova, Andrei N. Mardaryev, Chris G. Faulkes, Vladimir A. Botchkarev
Publikováno v:
J Invest Dermatol
Naked mole-rats (NMRs) (Heterocephalus glaber) are long-lived mammals that possess a natural resistance to cancer and other age-related pathologies, maintaining a healthy life span >30 years. In this study, using immunohistochemical and RNA-sequencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ee3316196b03416b4724f0fa20171e
https://doi.org/10.1016/j.jid.2022.04.028
https://doi.org/10.1016/j.jid.2022.04.028
Autor:
Andrew T. McKenzie, Ariel Zeleznikow-Johnston, Jordan S. Sparks, Oge Nnadi, John Smart, Keith Wiley, Michael A. Cerullo, Aschwin de Wolf, Francesca Minerva, Ramón Risco, George M. Church, João Pedro de Magalhães, Emil F. Kendziorra
Publikováno v:
Frontiers in Medical Technology, Vol 6 (2024)
When faced with the prospect of death, some people would prefer a form of long-term preservation that may allow them to be restored to healthy life in the future, if technology ever develops to the point that this is feasible and humane. Some believe
Externí odkaz:
https://doaj.org/article/31441b0faf144af7be78428e5b204c57
Autor:
Gabriel Arantes dos Santos, Kasit Chatsirisupachai, Roberto A. Avelar, João Pedro de Magalhães
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Introduction Understanding changes in cell identity in cancer and ageing is of great importance. In this work, we analyzed how gene expression changes in human tissues are associated with tissue specificity during cancer and ageing using tra
Externí odkaz:
https://doaj.org/article/3bf8913d93d947f090dcb06299fb0d6e
Autor:
Bowen Song, Daiyun Huang, Yuxin Zhang, Zhen Wei, Jionglong Su, João Pedro de Magalhães, Daniel J. Rigden, Jia Meng, Kunqi Chen
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 4, Pp 678-694 (2023)
As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs (lncRNAs), N6-methyladenosine (m6A) RNA methylation has been shown to participate in essential biological processes. Recent studies have revealed the distinct patterns
Externí odkaz:
https://doaj.org/article/64edc163a5604d168eefcf22d58a8d11
Autor:
Sybille Facca, Ahmed Abdelkader, Matthieu Ehlinger, Joao-Pedro-De-Magalhæs Correia, Christophe Cluzel, Nadia Bahlouli
Publikováno v:
Revue de Chirurgie Orthopédique et Traumatologique
SOFCOT Société Française de la chirurgie orthopédique
SOFCOT Société Française de la chirurgie orthopédique, Nov 2017, Paris, France. ⟨10.1016/j.rcot.2017.09.276⟩
SOFCOT Société Française de la chirurgie orthopédique, Nov 2017, Paris, France. ⟨10.1016/j.rcot.2017.09.276,⟩
SOFCOT Société Française de la chirurgie orthopédique
SOFCOT Société Française de la chirurgie orthopédique, Nov 2017, Paris, France. ⟨10.1016/j.rcot.2017.09.276⟩
SOFCOT Société Française de la chirurgie orthopédique, Nov 2017, Paris, France. ⟨10.1016/j.rcot.2017.09.276,⟩
Introduction L’arthroplastie totale de la hanche et l’arthroplastie totale du genou sont devenues des actes de plus en plus courants chez les personnes âgees. Cependant, il existe un risque eleve de fracture inter-prothetique (FI) pour les patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23735ebbf86c5a26e1b048c2a9793f3
https://hal.science/hal-03511513
https://hal.science/hal-03511513
Autor:
João Pedro de Magalhães
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Ageing is inherent to all human beings, yet why we age remains a hotly contested topic. Most mechanistic explanations of ageing posit that ageing is caused by the accumulation of one or more forms of molecular damage. Here, I propose that we
Externí odkaz:
https://doaj.org/article/20cd21f9e0da4fc1bf18e19e619345f9