Výsledky vyhledávání - "Joao L. C. Borges"

Akademický článek

Effects of evolocumab therapy and low LDL‐C levels on vitamin E and steroid hormones in Chinese and global patients with type 2 diabetes

Autor: Dirk J. Blom, Jiyan Chen, Zuyi Yuan, Joao L. C. Borges, Maria L. Monsalvo, Nan Wang, Andrew W. Hamer, Junbo Ge

Publikováno v: Endocrinology, Diabetes & Metabolism, Vol 3, Iss 2, Pp n/a-n/a (2020)

Abstract Aims We assessed the change from baseline in vitamin E, steroid hormones, adrenocorticotropic hormone (ACTH), and gonadotropins, overall and by lowest achieved low‐density lipoprotein‐cholesterol (LDL‐C) level, in patients with type 2

Externí odkaz: https://doaj.org/article/e2bba324a55d44e79cbce262e91d63d9

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EFFECTS OF HUMAN PANCREATIC TUMOUR GROWTH HORMONE RELEASING FACTOR ON GROWTH HORMONE AND SOMATOMEDIN C LEVELS IN PATIENTS WITH IDIOPATHIC GROWTH HORMONE DEFICIENCY

Autor: William S. Evans, Richard W. Furlanetto, Joachim Spiess, Donald L. Kaiser, Marie C. Gelato, Alan D. Rogol, D. Lynn Loriaux, Robert M. MacLeod, Jean Rivier, Wylie Vale, Michael O. Thorner, George R. Merriam, Mary Lee Vance, Joao L. C. Borges, Robert M. Blizzard

Publikováno v: The Lancet. 322:119-124

Human pancreatic tumour growth hormone releasing factor (hpGRF-40) 10 micrograms/kg was administered intravenously to 6 normal young men and 12 adult patients who had presented in childhood with growth hormone (GH) deficiency (7 patients had isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40021abbbd09e9f389eba323abd32473
https://doi.org/10.1016/s0140-6736(83)90113-7

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Human pancreatic tumor GH-releasing factor

Autor: Wylie Vale, Michael O. Thorner, Michael J. Cronin, R. M. Blizzard, Jennifer L. Thominet, Alan D. Rogol, W. S. Evans, Richard W. Furlanetto, Robert M. MacLeod, Jean Rivier, Lawrence A. Frohman, Mary Lee Vance, Joao L. C. Borges

Publikováno v: Acta Neurochirurgica. 75:72-80

Within the past year, three similar peptides with specific growth hormone (GH) releasing effects have been extracted from human tissue, identified, and synthesized. Human pancreatic tumor GH releasing factor (I-40)-OH (hpGRF-40) was the sole hpGRF is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f86cacfe25c8998b5102ede4ceb63b
https://doi.org/10.1007/bf01406325

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The Self-Priming Effect of Gonadotropin-Releasing Hormone on Luteinizing Hormone Release: Observations Using Rat Anterior Pituitary Fragments and Dispersed Cells Continuously Perifused in Parallel*

Autor: Pattie Hellmann, William S. Evans, Donald L. Kaiser, Michael O. Thorner, David R. Uskavitch, Joao L. C. Borges

Publikováno v: Endocrinology. 114:861-867

To study in vitro the self-priming effect of GnRH on LH release, rat anterior pituitaries were prepared either as fragments or dispersed cells and continuously perifused in parallel chambers. The experimental groups consisted of rats killed at 0800 h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e7a37b16f3afd58198b0d3eb93e2d8
https://doi.org/10.1210/endo-114-3-861

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Ca+2Dependence of Gonadotropin-Releasing Hormone-Stimulated Luteinizing Hormone Secretion:in VitroStudies Using Continuously Perifused Dispersed Rat Anterior Pituitary Cells*

Autor: Donald L. Kaiser, Michael O. Thorner, William S. Evans, Joao L. C. Borges, Dorothy Scott

Publikováno v: Endocrinology. 113:557-562

A continuously perifused dispersed rat anterior pituitary cell system was used to determine the importance of calcium (Ca+2) on the release of LH by GnRH. In response to continuous exposure to 10 nM GnRH, LH was released in a biphasic fashion; arbitr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d398093c6b3875d9498f881846086440
https://doi.org/10.1210/endo-113-2-557

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Biphasic Luteinizing Hormone Secretion in Response to Gonadotropin-Releasing Hormone during Continuous Perifusion of Dispersed Rat Anterior Pituitary Cells: Changes in Total Release and the Phasic Components during the Estrous Cycle*

Autor: Michael O. Thorner, William S. Evans, Joao L. C. Borges, Beverly J. Boykin, Donald L. Kaiser

Publikováno v: Endocrinology. 112:535-542

In vivo studies in the human and both in vivo and in vitro studies in animals have shown that GnRH-stimulated LH release is a function of the gonadal steroid environment. Furthermore, when GnRH is given in a sustained manner, the pattern of LH releas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3b7650753c35211d4520014d06a5b0
https://doi.org/10.1210/endo-112-2-535

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Follicle-Stimulating Hormone-Secreting Pituitary Tumor with Concomitant Elevation of Serum α-Subunit Levels*

Autor: E. Chester Ridgway, Joao L. C. Borges, Michael O. Thorner, Alan D. Rogol, Kalman Kovacs

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 58:937-941

Hypersecretion of FSH and alpha-subunit was documented in a man with a pituitary adenoma that was previously diagnosed on clinical grounds as nonfunctioning who had been treated by transsphenoidal surgery and postoperative irradiation. Postoperativel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a0accd45800de3a15a32575addb311
https://doi.org/10.1210/jcem-58-5-937

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Effects of Intravenous, Subcutaneous, and Intranasal Administration of Growth Hormone (GH)-Releasing Hormone-40 on Serum GH Concentrations in Normal Men*

Autor: William S. Evans, Thomas R. Downs, Wylie Vale, Lawrence A. Frohman, Mary Lee Vance, Joao L. C. Borges, Randolph P. Sellers, Jean Rivier, Donald L. Kaiser, Michael O. Thorner

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 61:846-850

In addition to stimulating GH release in normal subjects, GH-releasing hormone-40 (GHRH-40) stimulates GH secretion in some adults and children with GH deficiency. Recognizing that GHRH-40 may have potential as a therapeutic agent for the treatment o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcdefa2ececdb83240d8c479bc2fa66
https://doi.org/10.1210/jcem-61-5-846

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Mesulergine, a new dopamine agonist: Effects on anterior pituitary function and kinetics

Autor: Horst F. Schran, R Lance Boyett, William S. Evans, Alan D. Rogol, Richard L. Elton, Michael O. Thorner, Donald L. Kaiser, Robert M. MacLeod, Joao L. C. Borges

Publikováno v: Clinical Pharmacology and Therapeutics. 36:696-703

We investigated the effects of single doses of mesulergine on basal and thyrotropin-releasing hormone (TRH)-stimulated serum levels of several anterior pituitary hormones in healthy men and defined its kinetics. We also compared the effects on serum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7525d98b73c7057ed528a68c02222966
https://doi.org/10.1038/clpt.1984.242

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Biological activity of a growth hormone-releasing factor secreted by a human tumor

Autor: D. A. Keefer, Alan D. Rogol, Michael J. Cronin, Ivan S. Login, Robert M. MacLeod, Joao L. C. Borges, Michael O. Thorner

Publikováno v: The American journal of physiology. 244(4)

A substance released by a pancreatic islet cell tumor induced signs and symptoms of acromegaly in a young woman. The culture medium in which the tumor was placed after resection was added to rat anterior pituitary cells and incubated in vitro. Both n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6d577726c08aa968279470b39bc45b
https://pubmed.ncbi.nlm.nih.gov/6404176

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