Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Joannie M Allaire"'
Autor:
Franziska A Graef, Larissa S Celiberto, Joannie M Allaire, Mimi T Y Kuan, Else S Bosman, Shauna M Crowley, Hyungjun Yang, Justin H Chan, Martin Stahl, Hongbing Yu, Candice Quin, Deanna L Gibson, Elena F Verdu, Kevan Jacobson, Bruce A Vallance
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009719 (2021)
Reducing food intake is a common host response to infection, yet it remains unclear whether fasting is detrimental or beneficial to an infected host. Despite the gastrointestinal tract being the primary site of nutrient uptake and a common route for
Externí odkaz:
https://doaj.org/article/0e0ea62074644ca3b0f075eb8663545f
Autor:
Shauna M Crowley, Xiao Han, Joannie M Allaire, Martin Stahl, Isabella Rauch, Leigh A Knodler, Bruce A Vallance
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008498 (2020)
We investigated the role of the inflammasome effector caspases-1 and -11 during Salmonella enterica serovar Typhimurium infection of murine intestinal epithelial cells (IECs). Salmonella burdens were significantly greater in the intestines of caspase
Externí odkaz:
https://doaj.org/article/038531766fc4486bbc499e93c5ab38da
Autor:
Xiao Han, Joannie M. Allaire, Shauna M. Crowley, Jocelyn J. Chan, Kelly Lau, Conghao Zhang, Simon A. Hirota, Kirk Bergstrom, Leigh A. Knodler, Bruce A. Vallance
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The host restricts Salmonella enterica serovar Typhimurium infection of the gut via inflammasome-dependent sloughing of infected epithelial cells. Here we determined that concurrent caspase 1/11-dependent release of the goblet cell-derived mucin, Muc
Externí odkaz:
https://doaj.org/article/6c6253954466475d80d23564be718074
Autor:
Jessica Gagné-Sansfaçon, Joannie M Allaire, Christine Jones, François Boudreau, Nathalie Perreault
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98751 (2014)
Intestinal epithelial cells express the Sonic and Indian hedgehog ligands. Despite the strong interest in gut hedgehog signaling in GI diseases, no studies have specifically addressed the singular role of intestinal epithelial cell Sonic hedgehog sig
Externí odkaz:
https://doaj.org/article/692420879a194425ac9d9e5605632267
Autor:
Laura Sauve, Kevan Jacobson, Joannie M. Allaire, Alison Lopez, Michael A. Irvine, Bruce A. Vallance, Boyan K. Tsankov
Publikováno v:
International Journal of Infectious Diseases, Vol 103, Iss, Pp 246-256 (2021)
International Journal of Infectious Diseases
International Journal of Infectious Diseases
Highlights What is known•Adults with comorbidities are more likely to suffer from severe manifestations of COVID-19•Children with COVID-19 have less severe disease manifestations than adults•Children may experience multisystem inflammatory synd
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 769-782 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Intestinal organoids have become indispensable tools for many gastrointestinal researchers, advancing their studies of nontransformed intestinal epithelial cells, and their roles in an array of diseases, including inflammatory bowel disease and colon
Autor:
Carsten Struve, Else S. Bosman, Xiaoxia Li, Hong Yang, Gregor S. D. Reid, Hong B. Yu, H Mirsepasi-Lauridsen, Adeline Sivignon, Sébastien G. Gouin, Nicolas Barnich, Bruce A. Vallance, Wayne Vogl, Abbas Fotovati, K Krogfelt, Kevan Jacobson, Caixia Ma, Andreas Petersen, Joannie M. Allaire
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 4:142-144
Background Ulcerative colitis (UC) is a chronic inflammatory condition linked to intestinal microbial dysbiosis, including the expansion of E. coli strains related to extra-intestinal pathogenic E. coli. These “pathobionts” exhibit pathogenic pro
Autor:
Hyungjun Yang, Harry Sokol, Else S. Bosman, Franziska A. Graef, Gregor S. D. Reid, Joannie M. Allaire, Caixia Ma, Hongbing Yu, Lisa C. Osborne, Bruce A. Vallance, Kevan Jacobson, Arthur Mortha, Qiaochu Liang, James A. Waschek
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (41), ⟨10.1073/pnas.2106634118⟩
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (41), ⟨10.1073/pnas.2106634118⟩
Proc Natl Acad Sci U S A
Group 3 innate lymphoid cells (ILC3s) control the formation of intestinal lymphoid tissues and play key roles in intestinal defense. They express neuropeptide vasoactive intestinal peptide (VIP) receptor 2 (VPAC2), through which VIP modulates their f
Autor:
Veronique Giroux, Nathalie Perreault, Vilcy Reyes Nicolás, Joannie M. Allaire, François Boudreau, Dianne Pupo Gómez, Alain B. Alfonso, Véronique Pomerleau
Publikováno v:
Cells, Vol 10, Iss 2954, p 2954 (2021)
Cells
Volume 10
Issue 11
Cells
Volume 10
Issue 11
FoxL1+-Telocytes (TCFoxL1+) are subepithelial cells that form a network underneath the epithelium. We have shown that without inflammatory stress, mice with loss of function in the BMP signalling pathway in TCFoxL1+ (BmpR1aΔFoxL1+) initiated colonic
Autor:
Deanna L. Gibson, Joannie M. Allaire, Franziska A. Graef, Hyungjun Yang, Candice Quin, Martin Stahl, Kevan Jacobson, Else S. Bosman, Hongbing Yu, Elena F. Verdu, Justin Y.H. Chan, Mimi T. Y. Kuan, Bruce A. Vallance, Larissa Sbaglia Celiberto, Shauna M. Crowley
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8 (2021)
PLoS Pathogens, Vol 17, Iss 8, p e1009719 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 8, p e1009719 (2021)
PLoS Pathogens
Reducing food intake is a common host response to infection, yet it remains unclear whether fasting is detrimental or beneficial to an infected host. Despite the gastrointestinal tract being the primary site of nutrient uptake and a common route for