Dynamic monitoring of myeloma minimal residual disease with targeted mass spectrometry

Autor: Somayya Noori, Charissa Wijnands, Pieter Langerhorst, Vincent Bonifay, Christoph Stingl, Cyrille Touzeau, Jill Corre, Aurore Perrot, Philippe Moreau, Hélène Caillon, Theo M. Luider, Thomas Dejoie, Joannes F. M. Jacobs, Martijn M. van Duijn

Publikováno v: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-3 (2023)

Externí odkaz: https://doaj.org/article/e52bdd75c9e24b729afcd826067fff7c

Retrospective Longitudinal Monitoring of Multiple Myeloma Patients by Mass Spectrometry Using Archived Serum Protein Electrophoresis Gels and De Novo Sequence Analysis

Autor: Somayya Noori, Marina Zajec, Henk Russcher, Andrei N. Tintu, Annemiek Broijl, Joannes F. M. Jacobs, Theo M. Luider, Yolanda B. de Rijke, Martijn M. vanDuijn

Publikováno v: HemaSphere, Vol 6, Iss 8, p e758 (2022)

Externí odkaz: https://doaj.org/article/435d81d9f2fb48aaa52a558d704a2b78

Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells

Autor: Florian Wimmers, Nikita Subedi, Nicole van Buuringen, Daan Heister, Judith Vivié, Inge Beeren-Reinieren, Rob Woestenenk, Harry Dolstra, Aigars Piruska, Joannes F. M. Jacobs, Alexander van Oudenaarden, Carl G. Figdor, Wilhelm T. S. Huck, I. Jolanda M. de Vries, Jurjen Tel

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

Plasmacytoid dendritic cells (pDC) are a pivotal component of the immune system. Here, the authors utilize single-cell microfluidics to interrogate the human pDC compartment and reveal a subset of type I IFN secreting pDCs that is regulated by stocha

Externí odkaz: https://doaj.org/article/5014ff7f8a254b8ab188443ef63dba4a

Data from Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients

Autor: Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen

Purpose: Electroporation of dendritic cells (DC) with mRNA encoding tumor-associated antigens (TAA) has multiple advantages compared to peptide loading. We investigated the immunologic and clinical responses to vaccination with mRNA-electroporated DC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0f20607083d68d6b75c913531bcc4e
https://doi.org/10.1158/1078-0432.c.6522750.v1

Glycoproteomics in Cerebrospinal Fluid Reveals Brain-Specific Glycosylation Changes

Autor: Melissa Baerenfaenger, Merel A. Post, Pieter Langerhorst, Karin Huijben, Fokje Zijlstra, Joannes F. M. Jacobs, Marcel M. Verbeek, Hans J. C. T. Wessels, Dirk J. Lefeber

Publikováno v: International Journal of Molecular Sciences, 24
International Journal of Molecular Sciences, 24, 3
Baerenfaenger, M, Post, M A, Langerhorst, P, Huijben, K, Zijlstra, F, Jacobs, J F M, Verbeek, M M, Wessels, H J C T & Lefeber, D J 2023, ' Glycoproteomics in Cerebrospinal Fluid Reveals Brain-Specific Glycosylation Changes ', International Journal of Molecular Sciences, vol. 24, no. 3, 1937, pp. 1-17 . https://doi.org/10.3390/ijms24031937
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 1937
International Journal of Molecular Sciences, 24(3):1937, 1-17. Multidisciplinary Digital Publishing Institute (MDPI)

The glycosylation of proteins plays an important role in neurological development and disease. Glycoproteomic studies on cerebrospinal fluid (CSF) are a valuable tool to gain insight into brain glycosylation and its changes in disease. However, it is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631b721d32538e6e66c6296c94896e43
http://hdl.handle.net/2066/290590