Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joanneke E. Jansen"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
This perspective outlines an approach to improve mechanistic understanding of macrophages in inflammation and tissue homeostasis, with a focus on human inflammatory bowel disease (IBD). The approach integrates wet-lab and in-silico experimentation, d
Externí odkaz:
https://doaj.org/article/ccea25cf36374e4fa84116e061930c20
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 6, p e1010112 (2022)
Cell-cell communication is mediated by many soluble mediators, including over 40 cytokines. Cytokines, e.g. TNF, IL1β, IL5, IL6, IL12 and IL23, represent important therapeutic targets in immune-mediated inflammatory diseases (IMIDs), such as inflamm
Externí odkaz:
https://doaj.org/article/f2398cb73db84a9b8000a43ff7df9830
Autor:
Yin-Huai Chen, Eamonn A. Gaffney, Carolina V. Arancibia-Cárcamo, Jochen Schmitz, Maria Quaranta, Fiona Powrie, Lee A. Denson, Holm H. Uhlig, Subra Kugathasan, Stephen N. Sansom, Joanneke E. Jansen, Dominik Aschenbrenner, Mark Coles, Simon Travis, Karen Cox, Nicholas E. Ilott, Soumya Banerjee, Stephen Ho, Boyd Steere
Publikováno v:
Gut
ObjectiveDysregulated immune responses are the cause of IBDs. Studies in mice and humans suggest a central role of interleukin (IL)-23-producing mononuclear phagocytes in disease pathogenesis. Mechanistic insights into the regulation of IL-23 are pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932c4b0a155511dbaa25215408b332ed
https://www.repository.cam.ac.uk/handle/1810/324550
https://www.repository.cam.ac.uk/handle/1810/324550
Autor:
Mark Coles, Chen Y-H., Simon Travis, Subra Kugathasan, C Arancibia, Dominik Aschenbrenner, Stephen Ho, Boyd Steere, Nicholas E. Ilott, Joanneke E. Jansen, Karen Cox, M Quaranta, Fiona Powrie, Holm H. Uhlig, Jochen Schmitz, Eamonn A. Gaffney, Soumya Banerjee, Lee A. Denson, Stephen N. Sansom
BACKGROUND & AIMSDysregulated immune responses are the cause of inflammatory bowel diseases. Studies in both mice and humans suggest a central role of IL-23 producing mononuclear phagocytes in disease pathogenesis. Mechanistic insights into the regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a932ace5be13547185305b3775749fc3
https://ora.ox.ac.uk/objects/uuid:1506d593-e2cd-472c-979c-0f183e992a4f
https://ora.ox.ac.uk/objects/uuid:1506d593-e2cd-472c-979c-0f183e992a4f
Allochthonous resources can be found in many foodwebs and can influence both the structure and stability of an ecosystem. In order to better understand the role of how allochthonous resources are transferred as quarry from one predator-prey system to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c902c439bab4f4ee5ce71711169b35
https://ora.ox.ac.uk/objects/uuid:1429c037-0328-4498-924f-9ea6e9a9e803
https://ora.ox.ac.uk/objects/uuid:1429c037-0328-4498-924f-9ea6e9a9e803