Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joanne Van Hees"'
Autor:
Marie Decock, Laetitia El Haylani, Yi Hu, Steven O. Smith, Joanne Van Hees, Tzu-Chun Tang, Jean-Noël Octave, Ziao Fu, Stefan N. Constantinescu, Pascal Kienlen-Campard
Publikováno v:
Structure. 22:387-396
SummaryProteolysis of the β C-terminal fragment (β-CTF) of the amyloid precursor protein generates the Aβ peptides associated with Alzheimer’s disease. Familial mutations in the β-CTF, such as the A21G Flemish mutation, can increase Aβ secreti
Autor:
Jean-Noël Octave, Pascal Kienlen-Campard, Naouel Ben Khalifa, Sandra Huysseune, Stefan N. Constantinescu, Joanne Van Hees, Steven O. Smith, Bernadette Tasiaux
Publikováno v:
Cell Adhesion and Migration, Vol. 4, no. 2, p. 268-272 (2010)
Extensive research efforts have been conducted over the past decades to understand the processing of the Amyloid Precursor Protein (APP). APP cleavage leads to the production of the beta-amyloid peptide (Abeta), which is the major constituent of the
Autor:
Hélène Poirel, Judith Staerk, Stefan N. Constantinescu, Roberto D. Polakiewicz, John Rush, Christian Pecquet, Ronan Chaligne, Stéphane Giraudier, Kimberley A. Lee, Joanne Van Hees, Xiaowu Zhang, William Vainchenker, Jean-Marie Scheiff, Valerie Goss
Publikováno v:
Blood. 115:1037-1048
Constitutively active JAK2V617F and thrombopoietin receptor (TpoR) W515L/K mutants are major determinants of human myeloproliferative neoplasms (MPNs). We show that a TpoRW515 mutation (W515A), which we detected in 2 myelofibrosis patients, and the
Autor:
Naouel Ben Khalifa, Jean-Noël Ocatve, Steven O. Smith, Stefan N. Constantinescu, Antoine Verslype, Sandra Huysseune, Bernadette Tasiaux, Pascal Kienlen-Campard, Joanne Van Hees, Tu-chun Tang, Takeshi Sato
Publikováno v:
Alzheimer's & Dementia. 5
Autor:
Pascal Kienlen-Campard, Jean-Christophe Renauld, Naouel Ben Khalifa, Joanne Van Hees, Bernadette Tasiaux, Steven O. Smith, Stefan N. Constantinescu, Patrick Vandersmissen, Pierre J. Courtoy, Jean-Noël Octave
Publikováno v:
Alzheimer's & Dementia. 5
Autor:
Michael Girardot, Laurent Knoops, Dominik Selleslag, Lucienne Michaux, Mustapha Amyere, Joanne van Hees
Publikováno v:
Cancer genetics and cytogenetics. 192(2)
Autor:
Takeshi Sato, Sandra Huysseune, Stefan N. Constantinescu, Pascal Kienlen-Campard, Steven O. Smith, Bernadette Tasiaux, Jean-Noël Octave, Pierre J. Courtoy, Naouel Ben Khalifa, Joanne Van Hees
Publikováno v:
Alzheimer's & Dementia. 4
Autor:
Jeffrey Z. Fei, Saburo Aimoto, Mingli Li, Pascal Kienlen-Campard, Stefan N. Constantinescu, Joanne Van Hees, Jean-Noël Octave, Bernadette Tasiaux, Pierre J. Courtoy, Sandra Huysseune, Takeshi Sato, Steven O. Smith
Publikováno v:
The Journal of biological chemistry. 283(12)
The β-amyloid peptide (Aβ) is the major constituent of the amyloid core of senile plaques found in the brain of patients with Alzheimer's disease (AD). Aβ is produced by the sequential cleavage of the Amyloid Precursor Protein (APP) by β- and γ-
Publikováno v:
Alzheimer's & Dementia. 2
Autor:
Jean-Noël Octave, Sandra Huysseune, Pierre J. Courtoy, Joanne Van Hees, Bernadette Tasiaux, Takeshi Sato, Steven O. Smith, Pascal Kienlen-Campard, Saburo Aimoto, Jeffrey Z. Fei, Stefan N. Constantinescu, Mingli Li
Publikováno v:
Journal of Biological Chemistry. 283:12680