Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Joanne V. Allen"'
Autor:
Christine Marie Paul Lambert, Alan Girdwood, Andrew G. Leach, Catherine Bardelle, Andrew P. Garner, Helen Plant, J. S. Major, Brian Law, Dave Buttar, Kevin Blades, Louise Chapman, Nicola Colclough, Joanne V. Allen, Anthony M. Slater, Alexander G. Dossetter
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:5224-5229
A directed screen of a relatively small number of compounds, selected for kinase ATP pocket binding potential, yielded a novel series of hit compounds (1). Hit explosion on two binding residues identified compounds 27 and 43 as the best leads for an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab71f1ec550cbd864375b3a8152d5481
https://doi.org/10.1016/j.bmcl.2011.07.047
https://doi.org/10.1016/j.bmcl.2011.07.047
Autor:
Eric J. Thomas, Alan T. L. Lee, Anthony P. Green, Simon Hardy, Nicola Murdoch Heron, Joanne V. Allen
Publikováno v:
Tetrahedron Letters. 49:6352-6355
Modified Julia olefination reactions using aldehyde 27 and the benzothiazol-2-yl sulfones 13 and 39 provide efficient syntheses of alkenes 28 and 42, which are advanced intermediates for syntheses of bryostatins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0be19850e035821f9aeac908d9c60b51
https://doi.org/10.1016/j.tetlet.2008.08.075
https://doi.org/10.1016/j.tetlet.2008.08.075
Autor:
Peter William Rodney Caulkett, Scott Boyd, Clifford David Jones, Gordon S. Currie, Sarah Lackie, Emma Grange, Craig Johnstone, Barry R. Hayter, Harold Gaskin, Christopher D. Davies, Darren Mckerrecher, Rod B. Hargreaves, Mark L. Fenwick, Roger James, Rayner John Wall, Keith M. Johnson, Joanne V. Allen, Rolf Peter Walker, Suzanne S. Bowker
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:2103-2106
The identification, synthesis and SAR of a novel series of glucokinase activators is described. The interplay between lipophilicity, potency and physical properties is discussed, and compound 22 highlighted as having a suitable balance. In vivo pharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fc478426effd07bc452f839f361110
https://doi.org/10.1016/j.bmcl.2005.01.087
https://doi.org/10.1016/j.bmcl.2005.01.087
Publikováno v:
NIP & Digital Fabrication Conference. 16:473-476
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51f7a559ab22d01dd5bfc328c1c3d8d9
https://doi.org/10.2352/issn.2169-4451.2000.16.1.art00016_2
https://doi.org/10.2352/issn.2169-4451.2000.16.1.art00016_2
Polyamino acid-catalysed asymmetric epoxidation: Sodium percarbonate as a source of base and oxidant
Publikováno v:
Tetrahedron Letters. 40:5417-5420
New reaction conditions, using sodium percarbonate, are reported for the polyamino acid-catalysed asymmetric epoxidation of enones. Under these new conditions the rate of the uncatalysed reaction is reduced allowing an increased ratio of substrate to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4bc9a189925383a077546f8db4379a2
https://doi.org/10.1016/s0040-4039(99)01021-7
https://doi.org/10.1016/s0040-4039(99)01021-7
Autor:
Giles S. Ratcliffe, David C. Horwell, Julia A. H. Lainton, Joanne V. Allen, Jacqueline A. O'Neill
Publikováno v:
Letters in Peptide Science. 5:133-137
The design and synthesis of a structural motif which can mimic protein-protein interactions is described. These moieties, termed asdendroids (Greekdendron, a tree), are low-molecular-weight structures which are based on self-organising dendritic poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0296fe088b5bd49ce63c072251fa621
https://doi.org/10.1007/bf02443455
https://doi.org/10.1007/bf02443455
Autor:
Stanley M. Roberts, Joanne V. Allen, L. Eduardo Wu, Shubhasish Mukherjee, Matthew J. Griffiths, Sophie Bergeron, Natalie M. Williamson
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :3171-3180
The asymmetric oxidation of some enones (Table 1), selected dienones 3–5, and a trienone 13 is accomplished using poly-L-leucine or poly-D-leucine and urea hydrogen peroxide under non-aqueous conditions. One of the resultant epoxy ketones 6 has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13da8a86c5e593ad37cbe3f703c002ec
https://doi.org/10.1039/a805407j
https://doi.org/10.1039/a805407j
Publikováno v:
Tetrahedron: Asymmetry. 5:1895-1898
Ligands containing an enantiomerically pure oxazoline and a sulfur-containing tether have been examined for their ability to provide asymmetric induction in palladium catalysed allylic substitution reaction. The enantioselectivity obtained was found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96ae78122cf679aa3ce20791f57e7b5a
https://doi.org/10.1016/s0957-4166(00)86260-6
https://doi.org/10.1016/s0957-4166(00)86260-6
Publikováno v:
Tetrahedron: Asymmetry. 5:277-282
A series of enantiomerically pure oxazolines tethered to alcohols have been prepared. The use of these oxazolines has been demonstrated in the catalysed addition of diethylzinc to aromatic aldehydes to afford the corresponding secondary alcohols with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f47720841fce664cc78a9046e69de97d
https://doi.org/10.1016/s0957-4166(00)86184-4
https://doi.org/10.1016/s0957-4166(00)86184-4
Preparation of novel Sulfur and phosphorus containing oxazolines as ligands for asymmetric catalysis
Autor:
Joanne V. Allen, Steven John Coote, Christopher G. Frost, Graham J. Dawson, Ionathan M.J. Williams
Publikováno v:
Tetrahedron. 50:799-808
The preparation of enantiomerically pure liginds which contain both an oxazoline group and an additional sulfur or phosphorus donor atom are described. Methyithiomethyl, o -thioanisyl and thienyl oxazolines have been prepared in one step, and o -diph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f1c2e854186ff177ae9fcc5d56dd97a
https://doi.org/10.1016/s0040-4020(01)80795-x
https://doi.org/10.1016/s0040-4020(01)80795-x