Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joanne T deKay"'
Autor:
Victoria L. M. Herrera, Nicholas A. Bosch, Judith J. Lok, Mai Q. Nguyen, Kaitriona A. Lenae, Joanne T. deKay, Sergey V. Ryzhov, David B. Seder, Nelson Ruiz-Opazo, Allan J. Walkey
Publikováno v:
Translational Medicine Communications, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Background Cumulative research show association of neutrophils and neutrophil extracellular traps (NETs) with poor outcomes in severe COVID-19. However, to date, there is no curative intent therapy able to block neutrophil/NETs-mediated prog
Externí odkaz:
https://doaj.org/article/bfd51311bea44c489d92e19eed9b0408
Autor:
David J. Gagnon, Sergey V. Ryzhov, Meghan A. May, Richard R. Riker, Bram Geller, Teresa L. May, Sarah Bockian, Joanne T. deKay, Ashley Eldridge, Thomas Van der Kloot, Patricia Lerwick, Christine Lord, F. Lee Lucas, Patrick Mailloux, Barbara McCrum, Meghan Searight, Joel Wirth, Jonathan Zuckerman, Douglas Sawyer, David B. Seder
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Pneumonia is the most common infection after out-of-hospital cardiac arrest (OHCA) occurring in up to 65% of patients who remain comatose after return of spontaneous circulation. Preventing infection after OHCA may (1) reduce expo
Externí odkaz:
https://doaj.org/article/6b6bd016845849628adf375d567c04ef
Autor:
Joanne T. deKay, Ivette F. Emery, Jonathan Rud, Ashley Eldridge, Christine Lord, David J. Gagnon, Teresa L. May, Victoria L. M. Herrera, Nelson Ruiz-Opazo, Richard R. Riker, Douglas B. Sawyer, Sergey Ryzhov, David B. Seder
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract SARS-CoV-2 infection results in a spectrum of outcomes from no symptoms to widely varying degrees of illness to death. A better understanding of the immune response to SARS-CoV-2 infection and subsequent, often excessive, inflammation may in
Externí odkaz:
https://doaj.org/article/7f8cafdfa06e450c8c3f9913a5c5c788
Autor:
Joanne T. deKay, Teresa L. May, Richard R. Riker, Jonathan Rud, David J. Gagnon, Douglas B. Sawyer, David B. Seder, Sergey Ryzhov
Publikováno v:
Cytometry Part A. 103:153-161
We evaluated the number of CD26 expressing cells in peripheral blood of patients with COVID-19 within 72 h of admission and on day 4 and day 7 after enrollment. The majority of CD26 expressing cells were presented by CD3
Autor:
Ashley Eldridge, Victoria L. M. Herrera, David R. Gagnon, Richard R. Riker, Christine Lord, Joanne T. deKay, Jonathan Rud, Nelson Ruiz-Opazo, Teresa May, Sergey Ryzhov, Ivette F. Emery, David B. Seder, Douglas B. Sawyer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
SARS-CoV-2 infection results in a spectrum of outcomes from no symptoms to widely varying degrees of illness to death. A better understanding of the immune response to SARS-CoV-2 infection and subsequent, often excessive, inflammation may inform trea
Autor:
Igor Prudovsky, Sergey Ryzhov, Michael P. Robich, Amanda J. Favreau-Lessard, Robert A. Koza, Yodit R. Herrmann, Douglas B. Sawyer, Haifeng Yin, Joanne T. deKay
Publikováno v:
Journal of Molecular and Cellular Cardiology. 152:1-16
Background Myeloid cells play an important role in a wide variety of cardiovascular disorders, including both ischemic and non-ischemic cardiomyopathies. Neuregulin-1 (NRG-1)/ErbB signaling has recently emerged as an important factor contributing to
Autor:
Michael P Robich, Angela Kosta, Joshua Carver, Teaka Jackson, Bailey Shevenell, Joanne T deKay, Douglas Sawyer, Sergey V Ryzhov
Publikováno v:
Circulation. 144
Introduction: ErbB signaling contributes to the regulation of vascular function through endothelial cell differentiation, proliferation, survival, and regulation of barrier integrity. Patients with diabetes (DM) are at an increased risk for endotheli
Autor:
Sergey Ryzhov, Angela M. Kosta, Joanne T deKay, Joshua Carver, Michael P. Robich, Sergey Tsibulnikov, Douglas B. Sawyer, Emily Certo, Bailey Shevenell
Background We investigated the cell surface expression of ErbB receptors on left ventricular (LV) epicardial endothelial cells and CD105+ cells obtained from cardiac biopsies of patients undergoing coronary artery bypass grafting surgery (CABG). Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5a7508b74c68b5cde2b8a13a472dd90
https://doi.org/10.21203/rs.3.rs-903035/v1
https://doi.org/10.21203/rs.3.rs-903035/v1
Autor:
Sergey Ryzhov, Amanda J Lessard, Joanne T deKay, Yodit R. Herrmann, Haifeng Yin, Michael P. Robich, Douglas B. Sawyer
Publikováno v:
Circulation Research. 127
Introduction: Understanding molecular mechanisms underlying cardiac hypertrophy is crucial for protecting against cardiac remodeling, or slowing down its destined pathway to heart failure. Recent studies revealed that myeloid cells play an important
Autor:
Sarah M. Peterson, Douglas B. Sawyer, Emmanuel Boateng, Sergey Ryzhov, Michael P. Robich, Joanne T deKay
Publikováno v:
The FASEB Journal. 33