Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Joanne Sonstein"'
Autor:
Martha A Hutchens, Kathryn E Luker, Joanne Sonstein, Gabriel Núñez, Jeffrey L Curtis, Gary D Luker
Publikováno v:
PLoS Pathogens, Vol 4, Iss 9, p e1000153 (2008)
Innate immune responses are essential for controlling poxvirus infection. The threat of a bioterrorist attack using Variola major, the smallpox virus, or zoonotic transmission of other poxviruses has renewed interest in understanding interactions bet
Externí odkaz:
https://doaj.org/article/6b0c6718d8074b05a3266d96a2c5d98b
Autor:
Theresa M. Ames, Joanne Sonstein, Jeffrey L. Curtis, Christine M. Freeman, Alexandra L. McCubbrey
Publikováno v:
The Journal of Immunology. 189:112-119
The lung environment actively inhibits apoptotic cell (AC) uptake by alveolar macrophages (AMøs) via lung collectin signaling through signal regulatory protein α (SIRPα). Even brief glucocorticoid (GC) treatment during maturation of human blood mo
Autor:
Ying Zhao, J. Kelley Bentley, Emily R. Bowman, Nicholas W. Lukacs, Dina Schneider, Alan M. McLean, Jeffrey L. Curtis, Marc B. Hershenson, Joanne Sonstein, Marisa J. Linn, Jason B. Weinberg, Antonia P. Popova, Jun Young Hong, Uma S. Sajjan
Publikováno v:
The Journal of Immunology. 188:2894-2904
Recent studies link early rhinovirus (RV) infections to later asthma development. We hypothesized that neonatal RV infection leads to an IL-13–driven asthma-like phenotype in mice. BALB/c mice were inoculated with RV1B or sham on day 7 of life. Vir
Autor:
Jeffrey L. Curtis, Shyamala Ganesan, Joanne Sonstein, Andrea N. Faris, Uma S. Sajjan, Adam T. Comstock
Publikováno v:
The American Journal of Pathology. 180(1):61-72
Nontypeable Haemophilus influenzae (NTHi) is an important bacterial pathogen associated with lower respiratory tract colonization and with acute exacerbations and disease progression in chronic obstructive pulmonary disease (COPD). Why the immune sys
Autor:
Susan Murray, Jeffrey L. Curtis, Joanne Sonstein, Christine M. Freeman, Fernando J. Martinez, Catherine A. Meldrum, Christi Getty, Douglas A. Arenberg, Lisa McCloskey, Theresa M. Ames, MeiLan K. Han, Jill C. Todt, Timothy Polak, Lyrica X. Liu, Stephen W. Chensue
Publikováno v:
The Journal of Immunology. 184:6504-6513
Lung CD8+ T cells might contribute to progression of chronic obstructive pulmonary disease (COPD) indirectly via IFN-γ production or directly via cytolysis, but evidence for either mechanism is largely circumstantial. To gain insights into these pot
Autor:
Gary B. Huffnagle, Gerald T. Montano, Jeffrey L. Curtis, Michal A. Olszewski, Gwo-Hsiao Chen, John J. Osterholzer, Galen B. Toews, Rishi Surana, Jami E. Milam, Joanne Sonstein
Publikováno v:
The American Journal of Pathology. 174:932-943
Urease, a major virulence factor for Cryptococcus neoformans, promotes lethal meningitis/encephalitis in mice. The effect of urease within the lung, the primary site of most invasive fungal infections, is unknown. An established model of murine infec
Autor:
Joanne Sonstein, Michal A. Olszewski, Gary B. Huffnagle, Nicole R. Falkowski, Anne Hartman, Bethany B. Moore, Galen B. Toews, Rishi Surana
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 176:921-929
Staphylococcus aureus is a major pathogen complicating postsurgical care.To test the effect of sterile laparotomy (LAP) on pulmonary clearance of S. aureus in a murine model.Control and LAP mice were infected intranasally with 10(8) cfu of S. aureus.
Autor:
Patricia V. Basta, Annette T. Hastie, Stephen I. Rennard, Robert Paine, Neil E. Alexis, David Couper, Jeffrey L. Curtis, Robert J. Kaner, Elizabeth E. Carretta, Valerie R. Stolberg, Daichi Shimbo, Wanda K. O'Neal, Claire M. Doerschuk, Jeanette P. Brown, Christine M. Freeman, Prescott G. Woodruff, Joanne Sonstein, Sean Crudgington, Michelle Zeidler
Publikováno v:
Journal of Translational Medicine
Background: Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS) is a multi-center longitudinal, observational study to identify novel phenotypes and biomarkers of chronic obstructive pulmonary disease (COPD). In a subset of 300 subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5303cc5556983326f05f8527ddd6a7
Autor:
Timothy Polak, Antonello Punturieri, Jeffrey L. Curtis, Rebecca S. Alviani, Joanne Sonstein, Phil Copper
Publikováno v:
The Journal of Immunology. 173:1033-1042
The innate immune response must be mobilized promptly yet judiciously via TLRs to protect the lungs against pathogens. Stimulation of murine peritoneal macrophage (PMφ) TLR4 or TLR3 by pathogen-associated molecular patterns (PAMPs) typically induces
Autor:
Jeffrey L. Curtis, Joanne Sonstein, Julie K. Eisenbraun, Jun Chen, Raymond Yung, Ru Ran Mo, Ronald A. Craig, Lloyd M. Stoolman
Publikováno v:
The Journal of Immunology. 171:745-753
D10.G4.1 (D10) cells, a murine conalbumin-reactive Th2 cell line, made to overexpress the β2 integrin LFA-1 by pharmacological manipulation or by transfection become autoreactive and are capable of inducing in vivo autoimmunity. However, whether thi