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Autor:
Leighton Howells, Joanne Shelley, Enock Delaporte, Marjorie A. Egan, Dennis C. Dean, Elizabeth Price, A. David Rodrigues, Albie Santos, Donald E. Slaughter, Gregory J. Gatto
Publikováno v:
Journal of biomolecular screening. 6(4)
High throughput inhibition screens for human cytochrome P450s (CYPs) are being used in preclinical drug metabolism to support drug discovery programs. The versatility of scintillation proximity assay (SPA) technology has enabled the development of a