Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joanne Saye"'
Autor:
Paul Richardson, Steven Masson, Ashwin Dhanda, Ewan Forrest, Ankur Srivastava, Pauline Dundas, Lynsey Corless, Jennifer Towey, Neil Rajoriya, Christopher Oldroyd, Sarah Morgan, James Maurice, Richard Aspinall, Joanne McDonagh, Sara Bardell, Richard Parker, Vanessa Hebditch, Michael Allison, Ryan Buchanan, Robert Goldin, Steve Hood, Joanne Sayer, Vikram Bains, J Ryan, Thomas Phillips, Seonaid Anderson, Ian Davidson, Ian Webzell, Victoria Lavers, Nicole Rainford, Arron Jones, Emma Stennett, Jeff Fernandez, Erica Forster, Dennis Freshwater, Ruth Gailer, Deborah Lindsay, Tania Nurun, Elizabeth Oxley, Sally Pannifex, Graham Parsons, Mandy Smith, Roya Vaziri, Andrew Wellstead
Publikováno v:
BMJ Open Gastroenterology, Vol 10, Iss 1 (2023)
Objective Alcohol-related liver disease (ALD) is the most common cause of liver-related ill health and liver-related deaths in the UK, and deaths from ALD have doubled in the last decade. The management of ALD requires treatment of both liver disease
Externí odkaz:
https://doaj.org/article/b956417e8f024053a61438377f3ac920
Autor:
James Fikes, Mary Ann Gorko, Joanne Saye, Andy Zuvich, Patricia Bentley, David Brott, Melody Diamond, Pam Campbell, Letitia Cheatham
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:190-196
Introduction Drug-induced glucose dysregulation and insulin resistance have been associated with weight gain and potential induction and/or exacerbation of diabetes mellitus in the clinic suggesting they may be safety biomarkers when developing antip
Autor:
Sena Garber, Susan Erickson-Viitanen, Susan Jeffrey, Lee T. Bacheler, Beverly C. Cordova, Joanne Saye, George L. Trainor, Pamela Cawood, Greg D. Harris, Janan Jona, Ronald M. Klabe, Robert F. Kaltenbach, Marc Davies, Getman Daniel P, Sharon Diamond, Kelly Logue
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:3021-3028
Human immunodeficiency virus (HIV) protease inhibitors (PIs) are important components of many highly active antiretroviral therapy regimens. However, development of phenotypic and/or genotypic resistance can occur, including cross-resistance to other
Autor:
Shamik Parikh, Serge Jabbour, Jean M. Whaley, David W. Boulton, Timothy P. Reilly, James F. List, Joanne Saye, Mark Tirmenstein, Simon M. Poucher
Publikováno v:
Postgraduate medicine. 124(4)
Sodium-glucose co-transporter 2 (SGLT2) plays a key role in glucose homeostasis as the key transporter responsible for most renal glucose reabsorption in the proximal tubules of the kidney. Dapagliflozin is a potent, selective, and reversible inhibit
Autor:
Steven Bai, George L. Trainor, Keith J. Miller, Paul J. Gilligan, John F. McElroy, Todd Clarke, Karen Heman, Liqi He, Joanne Saye, Carol M. Krause, David W. Robertson, Yu-Wen Li, Lawrence W. Fitzgerald, Snjezana Lelas, Paul Hartig, Anne Marshall, Scott J. Grossman, Kathyrn Ward, Kim L. Zeller, Harvey Wong, Stephen P Arneric, Ge Zhang, Robert Zaczek
Publikováno v:
Journal of medicinal chemistry. 52(9)
This report describes the syntheses and structure-activity relationships of 8-(substituted pyridyl)pyrazolo[1,5-a]-1,3,5-triazine corticotropin releasing factor receptor-1 (CRF(1)) receptor antagonists. These CRF(1) receptor antagonists may be potent
Autor:
Thomas H. Hutchinson, Stewart F. Owen, Joanne Saye, Matthew J. Winter, Emma Giltrow, John P. Sumpter, Duane B. Huggett
Publikováno v:
Aquatic toxicology (Amsterdam, Netherlands). 82(3)
On the premise that human medicines may potentially induce similar pharmacological and toxicological profiles in fish and other lower vertebrates, we have applied this comparative approach to beta-adrenergic receptor antagonists ('beta-blockers') whi
Publikováno v:
Annals of the New York Academy of Sciences. 892:ix-x