Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Joanne R. Doherty"'
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
PDF file - 116K, Structure of the MCT1 inhibitors AR-C122982 (SR13800) and AR-C155858 (SR13801). Cell cycle analysis, viability, clonogenecity and lactate transport in the indicated cells treated with SR13800. Proliferation of MCF7 cells overexpressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe12409ad19b0950a2f681d67ed0966
https://doi.org/10.1158/0008-5472.22400951.v1
https://doi.org/10.1158/0008-5472.22400951.v1
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
PDF file - 358K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6b97dd482feca7cdabd8a4f8c44264
https://doi.org/10.1158/0008-5472.22400930.v1
https://doi.org/10.1158/0008-5472.22400930.v1
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
PDF file - 728K, Immunohistochemistry analyses of MCT1 and MCT4, and survival and tumor analyses of Raji lymphoma and T47D breast cancer cell xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b170a93eb0713e2f3dacbbd553e152af
https://doi.org/10.1158/0008-5472.22400936
https://doi.org/10.1158/0008-5472.22400936
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
PDF file - 78K, Effects of combined treatment of SR13800 and metformin on intracellular lactate and proliferation of Raji BL cells, and upon the proliferation of MCT1-expressing lymphoma and breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639e5520a6337fd6079d4a3d6dd7c162
https://doi.org/10.1158/0008-5472.22400942
https://doi.org/10.1158/0008-5472.22400942
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
PDF file - 366K, MYC, MCT1, MCT2, MCT3 and MCT4 mRNA levels in human tumors and survival analysis of human breast and lung cancer patients expressing high levels of both MYC and MCT1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cc1974db6d8b12008a1931dd880cd2
https://doi.org/10.1158/0008-5472.22400957.v1
https://doi.org/10.1158/0008-5472.22400957.v1
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
PDF file - 142K, MCT1 inhibition blocks glycolysis in Burkitt lymphoma cells, without affecting the steady state levels of glycolytic enzymes. Schematic of glutathione (GSH) metabolism and levels of components of glutamylcysteine ligase (GCL) in Raji
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37288ca8c4ad780c9857da6051817453
https://doi.org/10.1158/0008-5472.22400945
https://doi.org/10.1158/0008-5472.22400945
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
PDF file - 332K, Schematic of selection for SR13800 resistance in Raji BL cells and levels of MCT1, MCT4 and LDH in SR13800-resistant cells. Mitotracker green staining of Raji BL cells treated with SR13800 and metformin. Schematic of metabolic pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5872ff810b58ae6711038fc3dd5bbb42
https://doi.org/10.1158/0008-5472.22400933.v1
https://doi.org/10.1158/0008-5472.22400933.v1
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
Myc oncoproteins induce genes driving aerobic glycolysis, including lactate dehydrogenase-A that generates lactate. Here, we report that Myc controls transcription of the lactate transporter SLC16A1/MCT1 and that elevated MCT1 levels are manifest in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::278c5453687c2e19e6ace386d7db2b96
https://doi.org/10.1158/0008-5472.c.6505727
https://doi.org/10.1158/0008-5472.c.6505727
Autor:
John L. Cleveland, William R. Roush, Keziban Unsal-Kacmaz, Andrea T. Hooper, Thomas D. Bannister, Andrew A. Butler, K. Ganesh Kumar, Chi V. Dang, Yunqi Lu, Robert J. Rounbehler, Heide Marika Genau, Mariola Tortosa, Fangzheng Li, Jitendra K. Mishra, Antonio L. Amelio, Mark A. Hall, Weimin Li, Mohammad Fallahi, Michael D. Cameron, Kristen E.N. Scott, Chunying Yang, Joanne R. Doherty
PDF file - 76K, Expression profiling, RNA-seq and MYC chromatin immunoprecipitation analyses of MCT1 in human P493-6 B cells. MCT1, MCT2, MCT3 and MCT4 mRNA levels in Raji BL and MCF7 breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62baf046d413870728ced468eee8156
https://doi.org/10.1158/0008-5472.22400954.v1
https://doi.org/10.1158/0008-5472.22400954.v1
Autor:
Kamyar Zahedi, Sharon Barone, Christina Destefano-Shields, Marybeth Brooks, Tracy Murray-Stewart, Matthew Dunworth, Weimin Li, Joanne R Doherty, Mark A Hall, Roger D Smith, John L Cleveland, Robert A Casero, Manoocher Soleimani
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184570 (2017)
Cisplatin-induced nephrotoxicity limits its use in many cancer patients. The expression of enzymes involved in polyamine catabolism, spermidine/spermine N1-acetyltransferase (SSAT) and spermine oxidase (SMOX) increase in the kidneys of mice treated w
Externí odkaz:
https://doaj.org/article/1e3a8c94360248df90771470467f9e57
