Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joanne Pennock"'
Publikováno v:
Timms, K, Guo, H, Arkwright, P & Pennock, J 2022, ' Keratinocyte EGF signalling dominates in atopic dermatitis lesions: A comparative RNAseq analysis ', Experimental Dermatology . https://doi.org/10.1111/exd.14605
Atopic dermatitis (AD) remains a highly heterogenous disorder with a multifactorial aetiology. Whilst keratinocytes are known to play a fundamental role in AD, their contribution to the overall immune landscape in moderate-to-severe AD is still poorl
Autor:
Szu-Wei, Huang, Catherine, Walker, Joanne, Pennock, Kathryn, Else, Werner, Muller, Michael Jd, Daniels, Carolina, Pellegrini, David, Brough, Gloria, Lopez-Castejon, Sheena M, Cruickshank
Publikováno v:
Immunology and Cell Biology
Huang, S-W, Walker, C, Pennock, J, Else, K, Muller, W, Daniels, M, Pellegrini, C, Brough, D, Lopez-Castejon, G & Cruickshank, S 2017, ' P2X7 Receptor Dependent Tuning of Gut Epithelial Responses to Infection ', Immunology and cell biology, vol. 95, pp. 178-188 . https://doi.org/10.1038/icb.2016.75
Huang, S-W, Walker, C, Pennock, J, Else, K, Muller, W, Daniels, M, Pellegrini, C, Brough, D, Lopez-Castejon, G & Cruickshank, S 2017, ' P2X7 Receptor Dependent Tuning of Gut Epithelial Responses to Infection ', Immunology and cell biology, vol. 95, pp. 178-188 . https://doi.org/10.1038/icb.2016.75
Infection and injury of the gut are associated with cell damage and release of molecules such as extracellular adenosine 5′-triphosphate (ATP), which is recognised by the purinergic P2X7 receptor (P2X7R). P2X7R is widely expressed in the gut by ant