Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joanne Patman"'
Autor:
John S. Andrews, Subhash C. Annedi, Suman Rakhit, Shawn Maddaford, Jailall Ramnauth, Joanne Patman, Paul Renton, Namrta Bhardwaj
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:2540-2544
A series of substituted 2-aminobenzothiazole compounds have been synthesized and evaluated as nitric oxide synthase (NOS) inhibitors. Compound 14 shows activity in the nM range and is selective for the human neuronal NOS isoform. We have also evaluat
Publikováno v:
Medical Journal of Australia. 2:946-949
IN A DOUBLE-BLIND STUDY, 12 NORMAL SUBJECTS WERE GIVEN AMITRIPTYLINE, IN A DOSAGE OF 50 MG EVERY 12 HOURS, FOR FIVE DAYS AND WERE TESTED BY MEANS OF A MOTOR SKILL BATTERY WITH AND WITHOUT ALCOHOL ADMINISTRATION. COMPARISONS WITH AN EQUALLY CONSTITUTE