Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Joanne O'Dwyer"'
Autor:
William Whyte, Debkalpa Goswami, Sophie X. Wang, Yiling Fan, Niamh A. Ward, Ruth E. Levey, Rachel Beatty, Scott T. Robinson, Declan Sheppard, Raymond O’Connor, David S. Monahan, Lesley Trask, Keegan L. Mendez, Claudia E. Varela, Markus A. Horvath, Robert Wylie, Joanne O’Dwyer, Daniel A. Domingo-Lopez, Arielle S. Rothman, Garry P. Duffy, Eimear B. Dolan, Ellen T. Roche
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Drug delivery implants suffer from diminished release profiles due to fibrous capsule formation over time. Here, the authors use soft robotic actuation to modulate the immune response of the host to maintain drug delivery over the longer-term and to
Externí odkaz:
https://doaj.org/article/aa667d4033b34780a809474a674b58d7
Autor:
Caroline Herron, Conn L. Hastings, Clodagh Herron-Rice, Helena M. Kelly, Joanne O’Dwyer, Garry P. Duffy
Publikováno v:
Polymers, Vol 13, Iss 20, p 3568 (2021)
A reduction in blood supply to any limb causes ischaemia, pain and morbidity. Critical limb ischaemia is the most serious presentation of peripheral vascular disease. One in five patients with critical limb ischaemia will die within six months of dia
Externí odkaz:
https://doaj.org/article/1b89e89426864bd6bc41acbf1bee69f9
Autor:
Joanne O’Dwyer, Robert Murphy, Arlyng González-Vázquez, Lenka Kovarova, Martin Pravda, Vladimir Velebny, Andreas Heise, Garry P. Duffy, Sally Ann Cryan
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 779 (2021)
Heart failure has a five-year mortality rate approaching 50%. Inducing angiogenesis following a myocardial infarction is hypothesized to reduce cardiomyocyte death and tissue damage, thereby preventing heart failure. Herein, a novel nano-in-gel deliv
Externí odkaz:
https://doaj.org/article/a21fcaf49fcc4a58836dddb2d22007ed
Autor:
Joanne O’Dwyer, Megan Cullen, Sarinj Fattah, Robert Murphy, Smiljana Stefanovic, Lenka Kovarova, Martin Pravda, Vladimir Velebny, Andreas Heise, Garry P. Duffy, Sally Ann Cryan
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 513 (2020)
Stromal-Derived Factor 1α (SDF) is an angiogenic, chemotactic protein with significant potential for applications in a range of clinical areas, including wound healing, myocardial infarction and orthopaedic regenerative approaches. The 26-min in viv
Externí odkaz:
https://doaj.org/article/d4b1b26ac1bf4e6eb4145cd5301eb376
Autor:
Sally-Ann Cryan, Joanne O’Dwyer, Saltuk B. Hanay, Andreas Heise, Fergal J. O'Brien, Fernando de Oliveira, Matthew G. Haugh, Scott D. Kimmins
Publikováno v:
ACS macro letters. 7(8)
Crosslinking of tryptophan (Trp) containing copolypeptides with varying ratios of benzyl-l-glutamate (BLG) and Nα-(carbobenzyloxy)-l-lysine (Z-Lys) is achieved by the selective reaction with hexamethylene-bis-TAD (bisTAD). Conversion of the resultin
Autor:
Ruairí P. Brannigan, Fergal J. O'Brien, Shona O’Brien, Rita I. R. Ibanez, Sally-Ann Cryan, Joanne O’Dwyer, Bing Wu, Andreas Heise
Publikováno v:
Journal of Materials Chemistry B. 8:7785-7791
Hydrogels are widely used for biomedical applications such as drug delivery, tissue engineering, or wound healing owing to their mimetic properties in relation to biological tissues. The generation of peptide-based hydrogels is a topic of interest du
Autor:
Conn L. Hastings, Helena M. Kelly, Caroline C. Herron, Clodagh Herron-Rice, Garry P. Duffy, Joanne O’Dwyer
Publikováno v:
Polymers, Vol 13, Iss 3568, p 3568 (2021)
Polymers
Volume 13
Issue 20
Polymers
Volume 13
Issue 20
A reduction in blood supply to any limb causes ischaemia, pain and morbidity. Critical limb ischaemia is the most serious presentation of peripheral vascular disease. One in five patients with critical limb ischaemia will die within six months of dia
Autor:
Saltuk B. Hanay, Emily J Ryan, Cathal J Kearney, Andreas Heise, Jessica Ramalho, Deirdre Fitzgerald-Hughes, Sally-Ann Cryan, Fergal J. O'Brien, Joanne O’Dwyer, Robert Murphy, Scott D. Kimmins
Publikováno v:
Journal of materials chemistry. B. 9(27)
Hydrogels are perfectly suited to support cell and tissue growth in advanced tissue engineering applications as well as classical wound treatment scenarios. Ideal hydrogel materials for these applications should be easy to produce, biocompatible, res
Autor:
Martin Pravda, Vladimir Velebny, Lenka Kovarova, Sally-Ann Cryan, Joanne O’Dwyer, Arlyng González-Vázquez, Andreas Heise, Robert Murphy, Garry P. Duffy
Publikováno v:
Pharmaceutics
Volume 13
Issue 6
Pharmaceutics. 2021, vol. 13, issue 6, p. 1-19.
Pharmaceutics, Vol 13, Iss 779, p 779 (2021)
Volume 13
Issue 6
Pharmaceutics. 2021, vol. 13, issue 6, p. 1-19.
Pharmaceutics, Vol 13, Iss 779, p 779 (2021)
Heart failure has a five-year mortality rate approaching 50%. Inducing angiogenesis following a myocardial infarction is hypothesized to reduce cardiomyocyte death and tissue damage, thereby preventing heart failure. Herein, a novel nano-in-gel deliv
Autor:
Saoirse O'Mahony, Michael O'Dwyer, Garry P. Duffy, Robert Wylie, Roisin E. O'Cearbhaill, Eimear B. Dolan, Joanne O’Dwyer
Publikováno v:
Adv Ther (Weinh)
Ovarian cancer is the most lethal gynecological malignancy with a global five-year survival rate of 30-50%. First-line treatment involves cytoreductive surgery and administration of platinum-based small molecules and paclitaxel. These therapies were