Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joanne Morley"'
Autor:
Angela Deakin, Graham Duddy, Steve Wilson, Steve Harrison, Judi Latcham, Mick Fulleylove, Sylvia Fung, Jason Smith, Mike Pedrick, Tom McKevitt, Leigh Felton, Joanne Morley, Diana Quint, Dilniya Fattah, Brian Hayes, Jade Gough, Roberto Solari
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107490 (2014)
Interleukin-2 inducible tyrosine kinase (ITK) is expressed in T cells and plays a critical role in signalling through the T cell receptor. Evidence, mainly from knockout mice, has suggested that ITK plays a particularly important function in Th2 cell
Externí odkaz:
https://doaj.org/article/d1d949c2f0704f36a96334e7c5b4b83c
Autor:
Christopher R. Wellaway, Ian R. Baldwin, Paul Bamborough, Daniel Barker, Michelle A. Bartholomew, Chun-wa Chung, Birgit Dümpelfeld, John P. Evans, Neal J. Fazakerley, Paul Homes, Steven P. Keeling, Xiao Q. Lewell, Finlay W. McNab, Joanne Morley, Deborah Needham, Margarete Neu, Antoon J. M. van Oosterhout, Anshu Pal, Friedrich B. M. Reinhard, Francesco Rianjongdee, Craig M. Robertson, Paul Rowland, Rishi R. Shah, Emma B. Sherriff, Lisa A. Sloan, Simon Teague, Daniel A. Thomas, Natalie Wellaway, Justyna Wojno-Picon, James M. Woolven, Diane M. Coe
Publikováno v:
Journal of Medicinal Chemistry. 65:633-664
The Janus family of tyrosine kinases (JAK1, JAK2, JAK3, and TYK2) play an essential role in the receptor signaling of cytokines that have been implicated in the pathogenesis of severe asthma, and there is emerging interest in the development of small
Autor:
Angela Bridges, Sandrine Jayne, Jennifer Schofield, Ana Sousa Manso, Duncan S. Holmes, Xi-Ping Zhang, Larissa Lezina, Michael T. McCabe, Mark James Bamford, Anastasia Wyce, David Jonathan Hirst, Máire A. Convery, Tom Slocombe, Andrew C. Pearce, Don O. Somers, Simon D. Wagner, Paul Scott-Stevens, Ann Louise Walker, Jonathan P. Hutchinson, Constantinos Demetriou, Cassie Messenger, Melissa C. Musso, Sian Evans, Ruth C. Barber, Joanne Morley, Thomas Gobbetti
Publikováno v:
The Journal of Biological Chemistry
B-cell lymphoma 6 (BCL6) is a zinc finger transcriptional repressor possessing a BTB–POZ (BR-C, ttk, and bab for BTB; pox virus and zinc finger for POZ) domain, which is required for homodimerization and association with corepressors. BCL6 has mult
Autor:
Jason C. Smith, Mike Pedrick, Tom McKevitt, Steve Wilson, Joanne Morley, Sylvia Fung, Angela M. Deakin, Leigh M. Felton, Graham Duddy, Steve Mark Harrison, Roberto Solari, Dilniya Fattah, Judi Latcham, Brian Hayes, Mick Fulleylove, Diana Quint, Jade Gough
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107490 (2014)
PLoS ONE
PLoS ONE
Interleukin-2 inducible tyrosine kinase (ITK) is expressed in T cells and plays a critical role in signalling through the T cell receptor. Evidence, mainly from knockout mice, has suggested that ITK plays a particularly important function in Th2 cell
Autor:
Elizabeth C. Jones, Patricia Carter, Joanne Morley, Sheri Long, Leslie D. McIntosh, Linda Black, Gerald L. Andriole, Arnold Bullock
Publikováno v:
Journal of Urology. 189
Characterisation of the allergic phenotype resulting from a shortened HDM challenge protocol in mice
Publikováno v:
Journal of Inflammation (London, England)
Background Most mouse models of house dust mite (HDM) challengeinduced allergic pulmonary inflammation utilise long challenge periods usually via the intranasal route that can typically last for up to 9 weeks. While these extended protocols are usefu