Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joanne Milot"'
Autor:
Louis-Philippe Boulet, Marie-Eve Boulay, Joanne Milot, François Maltais, Cameron J. Hague, Johane Lepage, Harvey O. Coxson
Publikováno v:
Respiration. 99:1090-1100
Background: The development of irreversible airway obstruction (IRAO) in asthma is related to lung/airway inflammatory and structural changes whose characteristics are likely influenced by exposure to tobacco smoke. Objective: To investigate the inte
Autor:
Joanne Milot, Louis-Philippe Boulet, Marie-Eve Boulay, Lara Bilodeau, Johane Lepage, François Maltais
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Louis-Philippe Boulet, Marie-Eve Boulay, Joanne Milot, Johane Lepage, Lara Bilodeau, François Maltais Research Center, Quebec Heart and Lung Institute-Laval University, Quebec, QC, Canada Background: There is a need to characterize the impact of the
Autor:
Candice M. Todd, Richard M. Watson, Joanne Milot, Brittany M. Salter, Paul M. O'Byrne, Desmond M. Murphy, Jonathan Sadeh, Louis-Philippe Boulet, Gail M. Gauvreau, Karen Howie
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 41:34-39
Neutrophils are effector cells recruited to airways in patients with asthma. Migration of neutrophils occurs predominantly through activation of the CXCR1 and CXCR2 receptors by CXC chemokines, including IL-8 and Gro-α. The dual CXCR1/CXCR2 antagoni
Autor:
Michel Laviolette, Suzanne Maahs, Veronica A. Swystun, Louis-Philippe Boulet, Irvin Mayers, Christopher Carlsten, Philip J. Lowe, Barbro Dahlén, Andrej Skerjanec, Miranda Bowen, Richard Leigh, Linda Hui, Beth E. Davis, Richard M. Watson, Gail M. Gauvreau, Kieran J. Killian, Joanne Milot, Anton Drollmann, Paul M. O'Byrne, J. Mark FitzGerald, Ann-Sofie Lantz, Karin Meiser, Nikolaos Lazarinis, Jonathan P. Arm, Donald W. Cockcroft
Publikováno v:
Journal of Allergy and Clinical Immunology. 138:1051-1059
Background Omalizumab is an established anti-IgE therapy for the treatment of allergic diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE antibody that binds IgE with higher affinity than omalizumab. Object
Autor:
Johane Lepage, Lara Bilodeau, Joanne Milot, Myriam Nadeau, Louis-Philippe Boulet, Marie-Eve Boulay, François Maltais
Publikováno v:
Respiratory medicine. 125
Background Asthma with incomplete reversibility of airway obstruction (IRAO) may often be associated to smoking-induced changes. Nevertheless, a high proportion of patients showing IRAO have never smoked. These patients with IRAO often share features
Publikováno v:
1.11 Clinical Problems - Asthma.
Background: Asthma may be associated with IRAO, either due to an acquired smoking-related component of COPD or to asthma-related airway structural changes. This so called asthma-COPD overlap syndrome has been poorly studied. Aim: To evaluate the comp
Autor:
Christopher Carlsten, Ann-Sofie Lantz, Philip J. Lowe, M. Laviolette, J. Mark FitzGerald, Richard Leigh, Joanne Milot, Barbro Dahlén, Miranda Bowen, Donald W. Cockcroft, Karin Meiser, Anton Drollmann, Paul M. O'Byrne, Linda Hui, Veronica A. Swystun, Jonathan P. Arm, Gail M. Gauvreau, Karin Strandberg, Beth E. Davis, Richard M. Watson, Andrej Skerjanec, Louis-Philippe Boulet, Irvin Mayers, S. Maahs, Kieran J. Killian
Publikováno v:
5.3 Allergy and Immunology.
Aim: QGE031 is a high-affinity humanized anti-IgE antibody in development for treatment of uncontrolled severe asthma. We predicted steady-state dose responses by fitting a mathematical model to PKPD data. Methods: Subjects with mild, atopic asthma (
Autor:
Joanne Milot, Mahmoud Rouabhia, Michel Laviolette, Eric Jacques, Jamila Chakir, Abdelhabib Semlali
Publikováno v:
Allergy. 65:1438-1445
To cite this article: Semlali A, Jacques E, Rouabhia M, Milot J, Laviolette M, Chakir J. Regulation of epithelial cell proliferation by bronchial fibroblasts obtained from mild asthmatic subjects. Allergy 2010; 65: 1438–1445. Abstract Background: B
Publikováno v:
Chest. 122:2217-2223
Background Current asthma guidelines suggest a series of criteria to assess if asthma is controlled. However, there is a need to develop a simple and practical method to quantify the degree of such control, both in clinical practice and research. Stu
Autor:
Michel Laviolette, Johanne Côté, Hélène Turcotte, André Cartier, Louis-Philippe Boulet, Joanne Milot, Jean-Luc Malo
Publikováno v:
Chest. 114:373-379
Background Patient evaluation of asthma severity and medication needs is mostly based on respiratory symptoms and may be influenced by changes in perception of bronchoconstriction-induced sensations. However, the influence of asthma medication on the